All Curated Mutation Sites in SARS-CoV-2 
Back to Mutation Home

 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

Show All
  
ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: COVID-19-35905853
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 35905853 A222V
S
S
COVID-19
R
L
View
2 35905853 A262S
S
S
COVID-19
R
L
View
3 35905853 A570D
S
S
COVID-19
R
L
View
4 35905853 A688V
S
S
COVID-19
R
L
View
5 35905853 D1118H
S
S
COVID-19
R
L
View
6 35905853 D138Y
S
S
COVID-19
R
L
View
7 35905853 D215G
S
S
COVID-19
R
L
View
8 35905853 D80A
S
S
COVID-19
R
L
View
9 35905853 E154K
S
S
COVID-19
R
L
View
10 35905853 E484K
S
S
COVID-19
R
L
View
11 35905853 E484Q
S
S
COVID-19
R
L
View
12 35905853 F32S
S
S
COVID-19
R
L
View
13 35905853 G142D
S
S
COVID-19
R
L
View
14 35905853 G184S
S
S
COVID-19
R
L
View
15 35905853 G769V
S
S
COVID-19
R
L
View
16 35905853 H49V
S
S
COVID-19
R
L
View
17 35905853 H655Y
S
S
COVID-19
R
L
View
18 35905853 K1191N
S
S
COVID-19
R
L
View
19 35905853 K417N
S
S
COVID-19
R
L
View
20 35905853 L18F
S
S
COVID-19
R
L
View
21 35905853 L452R
S
S
COVID-19
R
L
View
22 35905853 L54F
S
S
COVID-19
R
L
View
23 35905853 M153T
S
S
COVID-19
R
L
View
24 35905853 N440K
S
S
COVID-19
R
L
View
25 35905853 P199L
S
S
COVID-19
R
L
View
26 35905853 P26S
S
S
COVID-19
R
L
View
27 35905853 P272L
S
S
COVID-19
R
L
View
28 35905853 P67S
S
S
COVID-19
R
L
View
29 35905853 P681R
S
S
COVID-19
R
L
View
30 35905853 Q1071H
S
S
COVID-19
R
L
View
31 35905853 Q675H
S
S
COVID-19
R
L
View
32 35905853 Q677H
S
S
COVID-19
R
L
View
33 35905853 R246I
S
S
COVID-19
R
L
View
34 35905853 S12F
S
S
COVID-19
R
L
View
35 35905853 S13I
S
S
COVID-19
R
L
View
36 35905853 S477N
S
S
COVID-19
R
L
View
37 35905853 S982A
S
S
COVID-19
R
L
View
38 35905853 S98F
S
S
COVID-19
R
L
View
39 35905853 T1027I
S
S
COVID-19
R
L
View
40 35905853 T20N
S
S
COVID-19
R
L
View
41 35905853 T716I
S
S
COVID-19
R
L
View
42 35905853 V1228I
S
S
COVID-19
R
L
View
43 35905853 W152C
S
S
COVID-19
R
L
View
44 35905853 W152L
S
S
COVID-19
R
L
View
45 35905853 K68X
ORF8
ORF8
COVID-19
R
L
View
46 35905853 Q27X
ORF8
ORF8
COVID-19
R
L
View
47 35905853 R52I
ORF8
ORF8
COVID-19
R
L
View
48 35905853 S24L
ORF8
ORF8
COVID-19
R
L
View
49 35905853 Y73C
ORF8
ORF8
COVID-19
R
L
View
50 35905853 G172V
ORF3a
ORF3a
COVID-19
R
L
View
51 35905853 Q57H
ORF3a
ORF3a
COVID-19
R
L
View
52 35905853 A10708D COVID-19
R
L
View
53 35905853 A23063T COVID-19
R
L
View
54 35905853 A23403G COVID-19
R
L
View
55 35905853 A28111G COVID-19
R
L
View
56 35905853 A28281T COVID-19
R
L
View
57 35905853 C14408T COVID-19
R
L
View
58 35905853 C14676T COVID-19
R
L
View
59 35905853 C15279T COVID-19
R
L
View
60 35905853 C21575T COVID-19
R
L
View
61 35905853 C23271A COVID-19
R
L
View
62 35905853 C23604A COVID-19
R
L
View
63 35905853 C23709T COVID-19
R
L
View
64 35905853 C241T COVID-19
R
L
View
65 35905853 C27972T COVID-19
R
L
View
66 35905853 C28472T COVID-19
R
L
View
67 35905853 C28869T COVID-19
R
L
View
68 35905853 C28977T COVID-19
R
L
View
69 35905853 C3037T COVID-19
R
L
View
70 35905853 C3267T COVID-19
R
L
View
71 35905853 C5388A COVID-19
R
L
View
72 35905853 C5986T COVID-19
R
L
View
73 35905853 C913T COVID-19
R
L
View
74 35905853 D3L COVID-19
R
L
View
75 35905853 D614G COVID-19
R
L
View
76 35905853 G204R COVID-19
R
L
View
77 35905853 G23012A COVID-19
R
L
View
78 35905853 G24914C COVID-19
R
L
View
79 35905853 G25135T COVID-19
R
L
View
80 35905853 G28048T COVID-19
R
L
View
81 35905853 G28280C COVID-19
R
L
View
82 35905853 G28881A COVID-19
R
L
View
83 35905853 G28882A COVID-19
R
L
View
84 35905853 G28883C COVID-19
R
L
View
85 35905853 I2230T COVID-19
R
L
View
86 35905853 N1653D COVID-19
R
L
View
87 35905853 N501Y COVID-19
R
L
View
88 35905853 P218L COVID-19
R
L
View
89 35905853 P314L COVID-19
R
L
View
90 35905853 P681H COVID-19
R
L
View
91 35905853 R203K COVID-19
R
L
View
92 35905853 R2613C COVID-19
R
L
View
93 35905853 S235F COVID-19
R
L
View
94 35905853 T1001I COVID-19
R
L
View
95 35905853 T16176C COVID-19
R
L
View
96 35905853 T24506G COVID-19
R
L
View
97 35905853 T28282A COVID-19
R
L
View
98 35905853 T6954C COVID-19
R
L
View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.