All Curated Mutation Sites in SARS-CoV-2 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: COVID-19-35913920
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 35913920 D614G
S
S
COVID-19
R
View
2 35913920 E484K
S
S
COVID-19
R
View
3 35913920 E484Q
S
S
COVID-19
R
View
4 35913920 E780Q
S
S
COVID-19
R
View
5 35913920 L452R
S
S
COVID-19
R
View
6 35913920 N439K
S
S
COVID-19
R
View
7 35913920 N501Y
S
S
COVID-19
R
View
8 35913920 P681R
S
S
COVID-19
R
View
9 35913920 Y453F
S
S
COVID-19
R
View
10 35913920 L84S
NSP8
ORF1a
COVID-19
R
View
11 35913920 Q27X
NSP8
ORF1a
COVID-19
R
View
12 35913920 S24L
NSP8
ORF1a
COVID-19
R
View
13 35913920 L37F
NSP6
ORF1a
COVID-19
R
View
14 35913920 G15S
NSP5
ORF1a
COVID-19
R
View
15 35913920 G251V
NSP3
ORF1a
COVID-19
R
View
16 35913920 Q57H
NSP3
ORF1a
COVID-19
R
View
17 35913920 T1198K
NSP3
ORF1a
COVID-19
R
View
18 35913920 268delD
NSP2
ORF1a
COVID-19
R
View
19 35913920 I559V
NSP2
ORF1a
COVID-19
R
View
20 35913920 P585S
NSP2
ORF1a
COVID-19
R
View
21 35913920 T85I
NSP2
ORF1a
COVID-19
R
View
22 35913920 P504L
NSP13
ORF1b
COVID-19
R
View
23 35913920 Y541C
NSP13
ORF1b
COVID-19
R
View
24 35913920 A97V
NSP12
ORF1b
COVID-19
R
View
25 35913920 P323L
NSP12
ORF1b
COVID-19
R
View
26 35913920 G204R
N
N
COVID-19
R
View
27 35913920 I292T
N
N
COVID-19
R
View
28 35913920 P13L
N
N
COVID-19
R
View
29 35913920 R203K
N
N
COVID-19
R
View
30 35913920 S194L
N
N
COVID-19
R
View
31 35913920 V13L
N
N
COVID-19
R
View
32 35913920 A222V COVID-19
R
View
33 35913920 G476S COVID-19
R
View
34 35913920 96delH COVID-19
R
View
35 35913920 K417N COVID-19
R
View
36 35913920 L18F COVID-19
R
View
37 35913920 S477N
S
S
COVID-19
R
View
38 35913920 T20N COVID-19
R
View
39 35913920 T478I COVID-19
R
View
40 35913920 T478K COVID-19
R
View
41 35913920 V483A COVID-19
R
View
42 35913920 145delY COVID-19
R
View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.