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Virus Gene/Protein ORF1a ORF1b ORF3a S E M N ORF7a ORF7b ORF8 ORF1ab ORF9b ORF10 ORF6 ORF9c

Disease COVID-19All Cell line Cystic Fibrosis Pediatric Multisystem Inflammatory Disease, COVID-19 related Thrombosis, COVID-19 related HIV Infections

Description Genotype/Subtype Immune Target gene Clinical data Treatment Location Sequence data

For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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ORF1a

  

ORF1b

  

ORF3a

  

3CLpro

  

3'UTR

  

5'UTR

  

RBD

  

ORF7b-ORF8

  

upstream of N

  

Furin cleavage site

  

E

  

endoRNase

  

Exonuclease

  

S

  

NSP13

  

NSP3

  

M

  

Mpro

  

Methyltransferase

  

N

  

NSP14

  

NSP12

  

Non-coding region

  

NP

  

NS3

  

NS7a

  

NS7b

  

NS8

  

NSP5

  

NSP1

  

NSP10

  

NSP11

  

NSP15

  

NSP16

  

NSP2

  

NSP4

  

NSP6

  

NSP7

  

NSP8

  

NSP9

  

NTD

  

ORF8

  

ORF1ab

  

ORF9b

  

ORF10

  

ORF3

  

ORF6

  

ORF7a

  

ORF7b

  

ORF9

  

ORF9c

  

PLpro

  

RdRp

  

RBM

  

Replicase

  

RNA primase

  

• Mutation
• Sequence

ID	PMID	Mutation	Gene/Protein/Region	Encoding Gene/Protein	Disease	Description	Detail
1	35966675	K856R	ORF1ab	ORF1ab	COVID-19	G R S C L	View
2	35966675	S2083I	ORF1ab	ORF1ab	COVID-19	G R S C L	View
3	35966675	A2710T	ORF1ab	ORF1ab	COVID-19	G R S C L	View
4	35966675	T3255I	ORF1ab	ORF1ab	COVID-19	G R S C L	View
5	35966675	P3395H	ORF1ab	ORF1ab	COVID-19	G R S C L	View
6	35966675	I3758V	ORF1ab	ORF1ab	COVID-19	G R S C L	View
7	35966675	I5967V	ORF1ab	ORF1ab	COVID-19	G R S C L	View
8	35966675	P13L	N	N	COVID-19	G R S C L	View
9	35966675	R203K	N	N	COVID-19	G R S C L	View
10	35966675	G204R	N	N	COVID-19	G R S C L	View
11	35966675	D3G	M	M	COVID-19	G R S C L	View
12	35966675	Q19E	M	M	COVID-19	G R S C L	View
13	35966675	A63T	M	M	COVID-19	G R S C L	View
14	35966675	T9I	E	E	COVID-19	G R S C L	View
15	35966675	H655Y	S	S	COVID-19	G R S C L	View
16	35966675	L18F	S	S	COVID-19	G R S C L	View
17	35966675	T20N	S	S	COVID-19	G R S C L	View
18	35966675	P26S	S	S	COVID-19	G R S C L	View
19	35966675	D138Y	S	S	COVID-19	G R S C L	View
20	35966675	R190S	S	S	COVID-19	G R S C L	View
21	35966675	K417T	S	S	COVID-19	G R S C L	View
22	35966675	E484K	S	S	COVID-19	G R S C L	View
23	35966675	T1027I	S	S	COVID-19	G R S C L	View
24	35966675	V1176F	S	S	COVID-19	G R S C L	View
25	35966675	T478K	S	S	COVID-19	G R S C L	View
26	35966675	A222V	S	S	COVID-19	G R S C L	View
27	35966675	T19R	S	S	COVID-19	G R S C L	View
28	35966675	E156G	S	S	COVID-19	G R S C L	View
29	35966675	F156/R157del	S	S	COVID-19	G R S C L	View
30	35966675	R158G	S	S	COVID-19	G R S C L	View
31	35966675	L452R	S	S	COVID-19	G R S C L	View
32	35966675	P681R	S	S	COVID-19	G R S C L	View
33	35966675	D950N	S	S	COVID-19	G R S C L	View
34	35966675	T95I	S	S	COVID-19	G R S C L	View
35	35966675	G181V	S	S	COVID-19	G R S C L	View
36	35966675	Q677P	S	S	COVID-19	G R S C L	View
37	35966675	Y145H	S	S	COVID-19	G R S C L	View
38	35966675	156del	S	S	COVID-19	G R S C L	View
39	35966675	157del	S	S	COVID-19	G R S C L	View
40	35966675	142delG	S	S	COVID-19	G R S C L	View
41	35966675	T120I	ORF7a	ORF7a	COVID-19	G R S C L	View
42	35966675	V82A	ORF7a	ORF7a	COVID-19	G R S C L	View
43	35966675	S26L	ORF3a	ORF3a	COVID-19	G R S C L	View
44	35966675	P4715L	ORF1ab	ORF1ab	COVID-19	G R S C L	View
45	35966675	G5063S	ORF1ab	ORF1ab	COVID-19	G R S C L	View
46	35966675	P5401L	ORF1ab	ORF1ab	COVID-19	G R S C L	View
47	35966675	2084delS	ORF1ab	ORF1ab	COVID-19	G R S C L	View
48	35966675	3674_G3676delL	ORF1ab	ORF1ab	COVID-19	G R S C L	View
49	35966675	3676_3678del	ORF1ab	ORF1ab	COVID-19	G R S C L	View
50	35966675	R203M	N	N	COVID-19	G R S C L	View
51	35966675	D377Y	N	N	COVID-19	G R S C L	View
52	35966675	D63G	N	N	COVID-19	G R S C L	View
53	35966675	D31/S33del	N	N	COVID-19	G R S C L	View
54	35966675	I82T	M	M	COVID-19	G R S C L	View
55	35966675	Q677H	S	S	COVID-19	G R S C L	View
56	35966675	N439K	S	S	COVID-19	G R S C L	View
57	35966675	Q675H	S	S	COVID-19	G R S C L	View
58	35966675	T29I	S	S	COVID-19	G R S C L	View
59	35966675	E484Q	S	S	COVID-19	G R S C L	View
60	35966675	delH69/V70	S	S	COVID-19	G R S C L	View
61	35966675	D614G	S	S	COVID-19	G R S C L	View
62	35966675	P681H	S	S	COVID-19	G R S C L	View
63	35966675	N501Y	S	S	COVID-19	G R S C L	View
64	35966675	144del	S	S	COVID-19	G R S C L	View
65	35966675	A570D	S	S	COVID-19	G R S C L	View
66	35966675	T716I	S	S	COVID-19	G R S C L	View
67	35966675	S982A	S	S	COVID-19	G R S C L	View
68	35966675	D1118H	S	S	COVID-19	G R S C L	View
69	35966675	L5F	S	S	COVID-19	G R S C L	View
70	35966675	A701S	S	S	COVID-19	G R S C L	View
71	35966675	T724I	S	S	COVID-19	G R S C L	View
72	35966675	A67S	S	S	COVID-19	G R S C L	View
73	35966675	S13I	S	S	COVID-19	G R S C L	View
74	35966675	T618I	S	S	COVID-19	G R S C L	View
75	35966675	69_70del	S	S	COVID-19	G R S C L	View
76	35966675	W152R	S	S	COVID-19	R S C L	View
77	35966675	R346S	S	S	COVID-19	R S C L	View
78	35966675	A899S	S	S	COVID-19	R S C L	View
79	35966675	Q27X	ORF8	ORF8	COVID-19	R S C L	View
80	35966675	R52I	ORF8	ORF8	COVID-19	R S C L	View
81	35966675	Y73C	ORF8	ORF8	COVID-19	R S C L	View
82	35966675	E92K	ORF8	ORF8	COVID-19	R S C L	View
83	35966675	S253P	ORF3a	ORF3a	COVID-19	R S C L	View
84	35966675	E102K	ORF1ab	ORF1ab	COVID-19	R S C L	View
85	35966675	A859V	ORF1ab	ORF1ab	COVID-19	R S C L	View
86	35966675	T1246I	ORF1ab	ORF1ab	COVID-19	R S C L	View
87	35966675	D1639N	ORF1ab	ORF1ab	COVID-19	R S C L	View
88	35966675	P2287S	ORF1ab	ORF1ab	COVID-19	R S C L	View
89	35966675	D2980N	ORF1ab	ORF1ab	COVID-19	R S C L	View
90	35966675	D3222N	ORF1ab	ORF1ab	COVID-19	R S C L	View
91	35966675	G3278S	ORF1ab	ORF1ab	COVID-19	R S C L	View
92	35966675	S3687L	ORF1ab	ORF1ab	COVID-19	R S C L	View
93	35966675	L3691S	ORF1ab	ORF1ab	COVID-19	R S C L	View
94	35966675	T4090I	ORF1ab	ORF1ab	COVID-19	R S C L	View
95	35966675	A4921V	ORF1ab	ORF1ab	COVID-19	R S C L	View
96	35966675	D5429Y	ORF1ab	ORF1ab	COVID-19	R S C L	View
97	35966675	T1001I	ORF1ab	ORF1ab	COVID-19	R S C L	View
98	35966675	A1708D	ORF1ab	ORF1ab	COVID-19	R S C L	View
99	35966675	I2230T	ORF1ab	ORF1ab	COVID-19	R S C L	View
100	35966675	S1188L	ORF1ab	ORF1ab	COVID-19	R S C L	View
101	35966675	K1795Q	ORF1ab	ORF1ab	COVID-19	R S C L	View
102	35966675	E5665D	ORF1ab	ORF1ab	COVID-19	R S C L	View
103	35966675	S3675/F3677del	ORF1ab	ORF1ab	COVID-19	R S C L	View
104	35966675	c.-3delA	N	N	COVID-19	R S C L	View
105	35966675	G212V	N	N	COVID-19	R S C L	View
106	35966675	D3L	N	N	COVID-19	R S C L	View
107	35966675	S235F	N	N	COVID-19	R S C L	View
108	35966675	P80R	N	N	COVID-19	R S C L	View
109	35966675	S477N	S	S	COVID-19	G R S C L	View
110	35966675	A67V	S	S	COVID-19	G R S C L	View
111	35966675	142delG/Y145insI	S	S	COVID-19	G R S C L	View
112	35966675	211delN/L212insI	S	S	COVID-19	G R S C L	View
113	35966675	R214/215insEPE	S	S	COVID-19	G R S C L	View
114	35966675	G339D	S	S	COVID-19	G R S C L	View
115	35966675	S371L	S	S	COVID-19	G R S C L	View
116	35966675	S373P	S	S	COVID-19	G R S C L	View
117	35966675	S375F	S	S	COVID-19	G R S C L	View
118	35966675	K417N	S	S	COVID-19	G R S C L	View
119	35966675	N440K	S	S	COVID-19	G R S C L	View
120	35966675	G446S	S	S	COVID-19	G R S C L	View
121	35966675	E484A	S	S	COVID-19	G R S C L	View
122	35966675	Q493R	S	S	COVID-19	G R S C L	View
123	35966675	T547K	S	S	COVID-19	G R S C L	View
124	35966675	N679K	S	S	COVID-19	G R S C L	View
125	35966675	N764K	S	S	COVID-19	G R S C L	View
126	35966675	D796Y	S	S	COVID-19	G R S C L	View
127	35966675	N856K	S	S	COVID-19	G R S C L	View
128	35966675	Q954H	S	S	COVID-19	G R S C L	View
129	35966675	N969K	S	S	COVID-19	G R S C L	View
130	35966675	L981F	S	S	COVID-19	G R S C L	View
131	35966675	R346K	S	S	COVID-19	G R S C L	View
132	35966675	A701V	S	S	COVID-19	G R S C L	View
133	35966675	S12F	S	S	COVID-19	G R S C L	View