All Curated Mutation Sites in SARS-CoV-2 
Back to Mutation Home

 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

Show All
  
ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: COVID-19-35966679
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 35966679 T19R
S
S
COVID-19
G
L
View
2 35966679 T95I
S
S
COVID-19
G
L
View
3 35966679 G142D
S
S
COVID-19
G
L
View
4 35966679 E156G
S
S
COVID-19
G
L
View
5 35966679 157delF
S
S
COVID-19
G
L
View
6 35966679 158delR
S
S
COVID-19
G
L
View
7 35966679 L452R
S
S
COVID-19
G
L
View
8 35966679 T478K
S
S
COVID-19
G
L
View
9 35966679 P681R
S
S
COVID-19
G
L
View
10 35966679 D950N
S
S
COVID-19
G
L
View
11 35966679 P93S
ORF8
ORF8
COVID-19
G
L
View
12 35966679 T40I
ORF7b
ORF7b
COVID-19
G
L
View
13 35966679 V82A
ORF7a
ORF7a
COVID-19
G
L
View
14 35966679 T120I
ORF7a
ORF7a
COVID-19
G
L
View
15 35966679 S26L
ORF3
ORF3a
COVID-19
G
L
View
16 35966679 T77A
NSP6
ORF1a
COVID-19
G
L
View
17 35966679 V167L
NSP4
ORF1a
COVID-19
G
L
View
18 35966679 T492I
NSP4
ORF1a
COVID-19
G
L
View
19 35966679 A488S
NSP3
ORF1a
COVID-19
G
L
View
20 35966679 V932A
NSP3
ORF1a
COVID-19
G
L
View
21 35966679 P1228L
NSP3
ORF1a
COVID-19
G
L
View
22 35966679 P1469S
NSP3
ORF1a
COVID-19
G
L
View
23 35966679 A394V
NSP14
ORF1b
COVID-19
G
L
View
24 35966679 P77L
NSP13
ORF1b
COVID-19
G
L
View
25 35966679 G671S
NSP12
ORF1b
COVID-19
G
L
View
26 35966679 D63G
N
N
COVID-19
G
L
View
27 35966679 R203M
N
N
COVID-19
G
L
View
28 35966679 G215C
N
N
COVID-19
G
L
View
29 35966679 D377Y
N
N
COVID-19
G
L
View
30 35966679 I82T
M
M
COVID-19
G
L
View
31 35966679 W152L
S
S
COVID-19
G
L
View
32 35966679 E484K
S
S
COVID-19
G
L
View
33 35966679 G769V
S
S
COVID-19
G
L
View
34 35966679 P412H
NSP14
ORF1b
COVID-19
G
L
View
35 35966679 G439R
NSP13
ORF1b
COVID-19
G
L
View
36 35966679 S187L
N
N
COVID-19
G
L
View
37 35966679 Q418H
N
N
COVID-19
G
L
View
38 35966679 F28L
M
M
COVID-19
G
L
View
39 35966679 D614G
S
S
COVID-19
G
L
View
40 35966679 A423V
NSP12
ORF1b
COVID-19
G
I
L
View
41 35966679 M153T
S
S
COVID-19
G
L
View
42 35966679 P108S
NSP5
ORF1a
COVID-19
G
L
View
43 35966679 S543P
NSP3
ORF1a
COVID-19
G
L
View
44 35966679 P151L
N
N
COVID-19
G
L
View
45 35966679 P323L
NSP12
ORF1b
COVID-19
G
L
View
46 35966679 R203K
N
N
COVID-19
G
L
View
47 35966679 G204R
N
N
COVID-19
G
L
View
48 35966679 R287I
NSP16
ORF1b
COVID-19
G
L
View
49 35966679 P43L
NSP14
ORF1b
COVID-19
G
L
View
50 35966679 M234I
N
N
COVID-19
G
L
View
51 35966679 L54F
S
S
COVID-19
G
L
View
52 35966679 69delH
S
S
COVID-19
G
L
View
53 35966679 70delV
S
S
COVID-19
G
L
View
54 35966679 144delY
S
S
COVID-19
G
L
View
55 35966679 N501Y
S
S
COVID-19
G
L
View
56 35966679 A570D
S
S
COVID-19
G
L
View
57 35966679 P681H
S
S
COVID-19
G
L
View
58 35966679 T716I
S
S
COVID-19
G
L
View
59 35966679 S982A
S
S
COVID-19
G
L
View
60 35966679 D1118H
S
S
COVID-19
G
L
View
61 35966679 Q27X
ORF8
ORF8
COVID-19
G
L
View
62 35966679 R52I
ORF8
ORF8
COVID-19
G
L
View
63 35966679 Y73C
ORF8
ORF8
COVID-19
G
L
View
64 35966679 106delS
NSP6
ORF1a
COVID-19
G
L
View
65 35966679 107delG
NSP6
ORF1a
COVID-19
G
L
View
66 35966679 108delF
NSP6
ORF1a
COVID-19
G
L
View
67 35966679 T183I
NSP3
ORF1a
COVID-19
G
L
View
68 35966679 A890D
NSP3
ORF1a
COVID-19
G
L
View
69 35966679 I1412T
NSP3
ORF1a
COVID-19
G
L
View
70 35966679 E261D
NSP13
ORF1b
COVID-19
G
L
View
71 35966679 D3L
N
N
COVID-19
G
L
View
72 35966679 S235F
N
N
COVID-19
G
L
View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.