All Curated Mutation Sites in SARS-CoV-2 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: COVID-19-35966763
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 35966763 N440K
RBD
S
COVID-19
G
View
2 35966763 N501Y
RBD
S
COVID-19
G
View
3 35966763 Q493K
RBD
S
COVID-19
G
View
4 35966763 S477N
RBD
S
COVID-19
G
View
5 35966763 S500G
RBD
S
COVID-19
G
View
6 35966763 S500T
RBD
S
COVID-19
G
View
7 35966763 T478K
RBD
S
COVID-19
G
View
8 35966763 T500A
RBD
S
COVID-19
G
View
9 35966763 T500C
RBD
S
COVID-19
G
View
10 35966763 T500G
RBD
S
COVID-19
G
View
11 35966763 T500S
RBD
S
COVID-19
G
View
12 35966763 T500T
RBD
S
COVID-19
G
View
13 35966763 Y505H
RBD
S
COVID-19
G
View
14 35966763 E484A
RBD
S
COVID-19
View
15 35966763 G339D
RBD
S
COVID-19
View
16 35966763 G446S
RBD
S
COVID-19
View
17 35966763 G496S
RBD
S
COVID-19
View
18 35966763 K417N
RBD
S
COVID-19
View
19 35966763 Q498R
RBD
S
COVID-19
View
20 35966763 S371L
RBD
S
COVID-19
View
21 35966763 S373P
RBD
S
COVID-19
View
22 35966763 S375F
RBD
S
COVID-19
View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.