All Curated Mutation Sites in SARS-CoV-2

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The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.

Browse Data by Virus Gene/Protein/Region, Disease OR Description

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Virus Gene/Protein

Disease

Description

For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

Furin cleavage site

Methyltransferase

Non-coding region

Keyword: COVID-19-35992703

ID	PMID	Mutation	Gene/Protein/Region	Encoding Gene/Protein	Disease	Description	Detail
1	35992703	G1099D	S	S	COVID-19	G L	View
2	35992703	H146Q	S	S	COVID-19	G L	View
3	35992703	Q173H	S	S	COVID-19	G L	View
4	35992703	L5F	S	S	COVID-19	G L	View
5	35992703	S929I	S	S	COVID-19	G L	View
6	35992703	R408I	S	S	COVID-19	G L	View
7	35992703	V622F	S	S	COVID-19	G L	View
8	35992703	A846G	S	S	COVID-19	G L	View
9	35992703	Q677H	S	S	COVID-19	G L	View
10	35992703	T719I	S	S	COVID-19	G L	View
11	35992703	R158G	S	S	COVID-19	G L	View
12	35992703	T778A	S	S	COVID-19	G L	View
13	35992703	S1097L	S	S	COVID-19	G L	View
14	35992703	G142D	S	S	COVID-19	G	View
15	35992703	T19I	S	S	COVID-19	G	View
16	35992703	T19R	S	S	COVID-19	G	View
17	35992703	156_158delinsG	S	S	COVID-19	G	View
18	35992703	P93S	ORF8	ORF8	COVID-19	G L	View
19	35992703	A65V	ORF8	ORF8	COVID-19	G L	View
20	35992703	S67F	ORF8	ORF8	COVID-19	G L	View
21	35992703	A65T	ORF8	ORF8	COVID-19	G L	View
22	35992703	H73Y	ORF7a	ORF7a	COVID-19	G L	View
23	35992703	P34S	ORF7a	ORF7a	COVID-19	G L	View
24	35992703	S272G	ORF3	ORF3a	COVID-19	G L	View
25	35992703	D22Y	ORF3	ORF3a	COVID-19	G L	View
26	35992703	W128L	ORF3	ORF3a	COVID-19	G L	View
27	35992703	D155Y	ORF3	ORF3a	COVID-19	G L	View
28	35992703	L140F	ORF3	ORF3a	COVID-19	G L	View
29	35992703	A18T	NSP8	ORF1a	COVID-19	G L	View
30	35992703	D101A	NSP8	ORF1a	COVID-19	G L	View
31	35992703	A80V	NSP7	ORF1a	COVID-19	G L	View
32	35992703	T45I	NSP7	ORF1a	COVID-19	G L	View
33	35992703	Q208H	NSP6	ORF1a	COVID-19	G L	View
34	35992703	A260V	NSP5	ORF1a	COVID-19	G L	View
35	35992703	K12R	NSP4	ORF1a	COVID-19	G L	View
36	35992703	S481L	NSP4	ORF1a	COVID-19	G L	View
37	35992703	T60I	NSP4	ORF1a	COVID-19	G L	View
38	35992703	C5239T	NSP3	ORF1a	COVID-19	G R L	View
39	35992703	T5514C	NSP3	ORF1a	COVID-19	G R L	View
40	35992703	V932A	NSP3	ORF1a	COVID-19	G R L	View
41	35992703	Y840Y	NSP3	ORF1a	COVID-19	G R L	View
42	35992703	P402T	NSP3	ORF1a	COVID-19	G L	View
43	35992703	N873D	NSP3	ORF1a	COVID-19	G L	View
44	35992703	A1537S	NSP3	ORF1a	COVID-19	G L	View
45	35992703	I1413F	NSP3	ORF1a	COVID-19	G L	View
46	35992703	N1284S	NSP3	ORF1a	COVID-19	G L	View
47	35992703	V61I	NSP3	ORF1a	COVID-19	G L	View
48	35992703	Y1185C	NSP3	ORF1a	COVID-19	G L	View
49	35992703	N444S	NSP3	ORF1a	COVID-19	G L	View
50	35992703	G250V	NSP3	ORF1a	COVID-19	G L	View
51	35992703	S1682F	NSP3	ORF1a	COVID-19	G L	View
52	35992703	T182I	NSP3	ORF1a	COVID-19	G L	View
53	35992703	T350I	NSP3	ORF1a	COVID-19	G L	View
54	35992703	N1587D	NSP3	ORF1a	COVID-19	G L	View
55	35992703	T199I	NSP3	ORF1a	COVID-19	G L	View
56	35992703	T388I	NSP2	ORF1a	COVID-19	G L	View
57	35992703	S36N	NSP2	ORF1a	COVID-19	G L	View
58	35992703	K67N	NSP2	ORF1a	COVID-19	G L	View
59	35992703	A26V	NSP2	ORF1a	COVID-19	G L	View
60	35992703	T439A	NSP2	ORF1a	COVID-19	G L	View
61	35992703	T151I	NSP16	ORF1b	COVID-19	G L	View
62	35992703	A34V	NSP16	ORF1b	COVID-19	G L	View
63	35992703	H174R	NSP16	ORF1b	COVID-19	G L	View
64	35992703	T105I	NSP15	ORF1b	COVID-19	G L	View
65	35992703	A353T	NSP14	ORF1b	COVID-19	G L	View
66	35992703	T372I	NSP14	ORF1b	COVID-19	G L	View
67	35992703	D496Y	NSP14	ORF1b	COVID-19	G L	View
68	35992703	D345Y	NSP14	ORF1b	COVID-19	G L	View
69	35992703	I334V	NSP13	ORF1b	COVID-19	G L	View
70	35992703	Y541C	NSP13	ORF1b	COVID-19	G L	View
71	35992703	D204E	NSP13	ORF1b	COVID-19	G L	View
72	35992703	A598V	NSP13	ORF1b	COVID-19	G L	View
73	35992703	T76I	NSP12	ORF1b	COVID-19	G L	View
74	35992703	L638F	NSP12	ORF1b	COVID-19	G L	View
75	35992703	P227L	NSP12	ORF1b	COVID-19	G L	View
76	35992703	T26I	NSP12	ORF1b	COVID-19	G L	View
77	35992703	G108V	NSP12	ORF1b	COVID-19	G L	View
78	35992703	85delM	NSP1	ORF1a	COVID-19	G L	View
79	35992703	R24C	NSP1	ORF1a	COVID-19	G L	View
80	35992703	E148G	NSP1	ORF1a	COVID-19	G L	View
81	35992703	D402Y	N	N	COVID-19	G L	View
82	35992703	R41Q	N	N	COVID-19	G L	View
83	35992703	T24N	N	N	COVID-19	G L	View
84	35992703	S37P	N	N	COVID-19	G L	View
85	35992703	E167K	M	M	COVID-19	G L	View
86	35992703	V62F	E	E	COVID-19	G L	View

Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note

D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.

G
The study mentioned the virus genotype/subtype information.

R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.

S
The study provided sequence information or accession numbers.

L
The study provided the geographic region/country of data origin.

C
The study provided clinical baseline information.

I
The study involved information related to immune.

T
The study involved host target genes.