All Curated Mutation Sites in SARS-CoV-2 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: COVID-19-36008511
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 36008511 D614G
S
S
COVID-19
R
C
L
View
2 36008511 H49Y
S
S
COVID-19
R
C
L
View
3 36008511 S477N
S
S
COVID-19
R
C
L
View
4 36008511 I68I
S
S
COVID-19
R
C
L
View
5 36008511 H68I
S
S
COVID-19
R
C
L
View
6 36008511 V68I
S
S
COVID-19
R
C
L
View
7 36008511 N501T
S
S
COVID-19
R
C
L
View
8 36008511 H655Y
S
S
COVID-19
R
C
L
View
9 36008511 P681R
S
S
COVID-19
R
C
L
View
10 36008511 L452R
S
S
COVID-19
R
C
L
View
11 36008511 S12F
S
S
COVID-19
R
C
L
View
12 36008511 P4715L
ORF1ab
ORF1ab
COVID-19
R
C
L
View
13 36008511 A4977V
RdRp
ORF1b
COVID-19
R
C
L
View
14 36008511 E64X
ORF8
ORF8
COVID-19
R
C
L
View
15 36008511 L84S
ORF8
ORF8
COVID-19
R
C
L
View
16 36008511 A43S
ORF7b
ORF7b
COVID-19
R
C
L
View
17 36008511 H78Y
ORF3a
ORF3a
COVID-19
R
C
L
View
18 36008511 S171L
ORF3a
ORF3a
COVID-19
R
C
L
View
19 36008511 I158V
ORF3a
ORF3a
COVID-19
R
C
L
View
20 36008511 V3718A
ORF1ab
ORF1ab
COVID-19
R
C
L
View
21 36008511 V3718F
ORF1ab
ORF1ab
COVID-19
R
C
L
View
22 36008511 V86F
ORF1ab
ORF1ab
COVID-19
R
C
L
View
23 36008511 E102K
ORF1ab
ORF1ab
COVID-19
R
C
L
View
24 36008511 E378V
N
N
COVID-19
R
C
L
View
25 36008511 A220V
N
N
COVID-19
R
C
L
View
26 36008511 N213Y
N
N
COVID-19
R
C
L
View
27 36008511 A35V
N
N
COVID-19
R
C
L
View
28 36008511 S202N
N
N
COVID-19
R
C
L
View
29 36008511 S235F
N
N
COVID-19
R
C
L
View
30 36008511 D402Y
N
N
COVID-19
R
C
L
View
31 36008511 R203K
N
N
COVID-19
R
C
L
View
32 36008511 G204R
N
N
COVID-19
R
C
L
View
33 36008511 G212V
N
N
COVID-19
R
C
L
View
34 36008511 T4090I
NSP8
ORF1a
COVID-19
R
C
L
View
35 36008511 L3691S
NSP6
ORF1a
COVID-19
R
C
L
View
36 36008511 A3529T
NSP5
ORF1a
COVID-19
R
C
L
View
37 36008511 G3278S
NSP5
ORF1a
COVID-19
R
C
L
View
38 36008511 D3222N
NSP4
ORF1a
COVID-19
R
C
L
View
39 36008511 P2110S
NSP3
ORF1a
COVID-19
R
C
L
View
40 36008511 A859V
NSP3
ORF1a
COVID-19
R
C
L
View
41 36008511 D1639N
NSP3
ORF1a
COVID-19
R
C
L
View
42 36008511 M1312I
NSP3
ORF1a
COVID-19
R
C
L
View
43 36008511 S2625F
NSP3
ORF1a
COVID-19
R
C
L
View
44 36008511 T1246I
NSP3
ORF1a
COVID-19
R
C
L
View
45 36008511 A5376V
NSP13
ORF1b
COVID-19
R
C
L
View
46 36008511 D5584Y
NSP13
ORF1b
COVID-19
R
C
L
View
47 36008511 A5620S
NSP13
ORF1b
COVID-19
R
C
L
View
48 36008511 N5827Y
NSP13
ORF1b
COVID-19
R
C
L
View
49 36008511 V5493F
NSP13
ORF1b
COVID-19
R
C
L
View
50 36008511 M6094I
Exonuclease
ORF1b
COVID-19
R
C
L
View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.