All Curated Mutation Sites in SARS-CoV-2 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

Show All
  
ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: COVID-19-36057416
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 36057416 D614G
S
S
COVID-19
R
L
View
2 36057416 C21614T
S
S
COVID-19
R
L
View
3 36057416 C21638T
S
S
COVID-19
R
L
View
4 36057416 G21974T
S
S
COVID-19
R
L
View
5 36057416 A22812C
S
S
COVID-19
R
L
View
6 36057416 G23012A
S
S
COVID-19
R
L
View
7 36057416 A23063T
S
S
COVID-19
R
L
View
8 36057416 C23525T
S
S
COVID-19
R
L
View
9 36057416 C24642T
S
S
COVID-19
R
L
View
10 36057416 G25088T
S
S
COVID-19
R
L
View
11 36057416 L18F
S
S
COVID-19
R
L
View
12 36057416 P26S
S
S
COVID-19
R
L
View
13 36057416 D138Y
S
S
COVID-19
R
L
View
14 36057416 K417T
S
S
COVID-19
R
L
View
15 36057416 E484K
S
S
COVID-19
R
L
View
16 36057416 N501Y
S
S
COVID-19
R
L
View
17 36057416 H655Y
S
S
COVID-19
R
L
View
18 36057416 T1027I
S
S
COVID-19
R
L
View
19 36057416 V1176F
S
S
COVID-19
R
L
View
20 36057416 Q94X
ORF7a
ORF7a
COVID-19
R
L
View
21 36057416 T27299C
ORF6
ORF6
COVID-19
R
L
View
22 36057416 I33T
ORF6
ORF6
COVID-19
R
L
View
23 36057416 C14408T
ORF1ab
ORF1ab
COVID-19
R
L
View
24 36057416 P4715L
ORF1ab
ORF1ab
COVID-19
R
L
View
25 36057416 A23403G
S
S
COVID-19
R
L
View
26 36057416 G28881A
N
N
COVID-19
R
L
View
27 36057416 G28883C
N
N
COVID-19
R
L
View
28 36057416 T29148C
N
N
COVID-19
R
L
View
29 36057416 G204R
N
N
COVID-19
R
L
View
30 36057416 I292T
N
N
COVID-19
R
L
View
31 36057416 R203K
N
N
COVID-19
R
L
View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.