All Curated Mutation Sites in SARS-CoV-2 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

Show All
  
ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: COVID-19-36145442
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 36145442 D614G
S
S
COVID-19
View
2 36145442 N501Y
S
S
COVID-19
View
3 36145442 E484K
S
S
COVID-19
I
View
4 36145442 T478K
S
S
COVID-19
View
5 36145442 L452R
S
S
COVID-19
View
6 36145442 P681R
S
S
COVID-19
View
7 36145442 T19R
S
S
COVID-19
View
8 36145442 158delR
S
S
COVID-19
View
9 36145442 E156G
S
S
COVID-19
View
10 36145442 157delF
S
S
COVID-19
View
11 36145442 D950N
S
S
COVID-19
View
12 36145442 G142D
S
S
COVID-19
View
13 36145442 T95I
S
S
COVID-19
View
14 36145442 P681H
S
S
COVID-19
View
15 36145442 T716I
S
S
COVID-19
View
16 36145442 70delV
S
S
COVID-19
View
17 36145442 69delH
S
S
COVID-19
View
18 36145442 S982A
S
S
COVID-19
View
19 36145442 144delY
S
S
COVID-19
View
20 36145442 D1118H
S
S
COVID-19
View
21 36145442 A570D
S
S
COVID-19
View
22 36145442 L18F
S
S
COVID-19
View
23 36145442 V1176F
S
S
COVID-19
View
24 36145442 T1027I
S
S
COVID-19
View
25 36145442 P26S
S
S
COVID-19
View
26 36145442 H655Y
S
S
COVID-19
View
27 36145442 R190S
S
S
COVID-19
View
28 36145442 D138Y
S
S
COVID-19
View
29 36145442 T20N
S
S
COVID-19
View
30 36145442 K417T
S
S
COVID-19
View
31 36145442 V1104L
S
S
COVID-19
View
32 36145442 V1264L
S
S
COVID-19
View
33 36145442 T732A
S
S
COVID-19
View
34 36145442 A701V
S
S
COVID-19
View
35 36145442 K417N
S
S
COVID-19
View
36 36145442 D215G
S
S
COVID-19
View
37 36145442 D80A
S
S
COVID-19
View
38 36145442 V159L
S
S
COVID-19
View
39 36145442 242delL
S
S
COVID-19
View
40 36145442 L5F
S
S
COVID-19
View
41 36145442 243delA
S
S
COVID-19
View
42 36145442 D1259H
S
S
COVID-19
View
43 36145442 Q677H
S
S
COVID-19
View
44 36145442 A27S
S
S
COVID-19
View
45 36145442 R158S
S
S
COVID-19
View
46 36145442 T240I
S
S
COVID-19
View
47 36145442 E1258D
S
S
COVID-19
View
48 36145442 N1074S
S
S
COVID-19
View
49 36145442 P251L
S
S
COVID-19
View
50 36145442 K97E
S
S
COVID-19
View
51 36145442 S98F
S
S
COVID-19
View
52 36145442 R346K
S
S
COVID-19
View
53 36145442 244delL
S
S
COVID-19
View
54 36145442 Y160F
S
S
COVID-19
View
55 36145442 A222V
S
S
COVID-19
View
56 36145442 A146D
PLpro
ORF1a
COVID-19
View
57 36145442 P78L
PLpro
ORF1a
COVID-19
View
58 36145442 K233Q
PLpro
ORF1a
COVID-19
View
59 36145442 K93N
PLpro
ORF1a
COVID-19
View
60 36145442 E162D
PLpro
ORF1a
COVID-19
View
61 36145442 P323L
NSP12
ORF1b
COVID-19
View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.