All Curated Mutation Sites in SARS-CoV-2 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: COVID-19-36320663
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 36320663 G446S
S
S
COVID-19
G
R
I
L
View
2 36320663 R493Q
S
S
COVID-19
G
R
I
L
View
3 36320663 W152R
S
S
COVID-19
G
R
I
L
View
4 36320663 A27S
S
S
COVID-19
G
R
L
View
5 36320663 D405N
S
S
COVID-19
G
R
L
View
6 36320663 D614G
S
S
COVID-19
G
R
L
View
7 36320663 D796Y
S
S
COVID-19
G
R
L
View
8 36320663 E484A
S
S
COVID-19
G
R
L
View
9 36320663 F157L
S
S
COVID-19
G
R
L
View
10 36320663 G142D
S
S
COVID-19
G
R
L
View
11 36320663 G257S
S
S
COVID-19
G
R
L
View
12 36320663 G339H
S
S
COVID-19
G
R
L
View
13 36320663 H655Y
S
S
COVID-19
G
R
L
View
14 36320663 I210V
S
S
COVID-19
G
R
L
View
15 36320663 K147E
S
S
COVID-19
G
R
L
View
16 36320663 K417N
S
S
COVID-19
G
R
L
View
17 36320663 24delL
S
S
COVID-19
G
R
L
View
18 36320663 N440K
S
S
COVID-19
G
R
L
View
19 36320663 N460K
S
S
COVID-19
G
R
L
View
20 36320663 N501Y
S
S
COVID-19
G
R
L
View
21 36320663 N679K
S
S
COVID-19
G
R
L
View
22 36320663 N764K
S
S
COVID-19
G
R
L
View
23 36320663 N969K
S
S
COVID-19
G
R
L
View
24 36320663 25delP
S
S
COVID-19
G
R
L
View
25 36320663 26delP
S
S
COVID-19
G
R
L
View
26 36320663 P681H
S
S
COVID-19
G
R
L
View
27 36320663 Q498R
S
S
COVID-19
G
R
L
View
28 36320663 Q954H
S
S
COVID-19
G
R
L
View
29 36320663 R408S
S
S
COVID-19
G
R
L
View
30 36320663 S371F
S
S
COVID-19
G
R
L
View
31 36320663 S373P
S
S
COVID-19
G
R
L
View
32 36320663 S375F
S
S
COVID-19
G
R
L
View
33 36320663 S477N
S
S
COVID-19
G
R
L
View
34 36320663 T19I
S
S
COVID-19
G
R
L
View
35 36320663 T376A
S
S
COVID-19
G
R
L
View
36 36320663 T478K
S
S
COVID-19
G
R
L
View
37 36320663 V213G
S
S
COVID-19
G
R
L
View
38 36320663 Y505H
S
S
COVID-19
G
R
L
View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.