All Curated Mutation Sites in SARS-CoV-2 
Back to Mutation Home

 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
*Please select one option you are interested in, the page will be automatically redirected.
     
     

For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

Show All
  
ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: COVID-19-36405589
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 36405589 T19R
S
S
COVID-19
G
R
S
C
L
View
2 36405589 L452R
S
S
COVID-19
G
R
S
C
L
View
3 36405589 P681R
S
S
COVID-19
G
R
S
C
L
View
4 36405589 A684V
S
S
COVID-19
G
R
S
C
L
View
5 36405589 V1104L
S
S
COVID-19
G
R
S
C
L
View
6 36405589 I1114V
S
S
COVID-19
G
R
S
C
L
View
7 36405589 P3395H
ORF1ab
ORF1ab
COVID-19
G
R
S
C
L
View
8 36405589 P4715L
ORF1ab
ORF1ab
COVID-19
G
R
S
C
L
View
9 36405589 T3255I
ORF1ab
ORF1ab
COVID-19
G
R
S
C
L
View
10 36405589 S135R COVID-19
G
R
S
C
L
View
11 36405589 T842I COVID-19
G
R
S
C
L
View
12 36405589 G1307S COVID-19
G
R
S
C
L
View
13 36405589 L3027F COVID-19
G
R
S
C
L
View
14 36405589 T3090I COVID-19
G
R
S
C
L
View
15 36405589 L3201F COVID-19
G
R
S
C
L
View
16 36405589 R5716C COVID-19
G
R
S
C
L
View
17 36405589 T6564I COVID-19
G
R
S
C
L
View
18 36405589 T19I
S
S
COVID-19
G
R
S
C
L
View
19 36405589 V213G
S
S
COVID-19
G
R
S
C
L
View
20 36405589 G142D
S
S
COVID-19
G
R
S
C
L
View
21 36405589 S371F
S
S
COVID-19
G
R
S
C
L
View
22 36405589 T376A
S
S
COVID-19
G
R
S
C
L
View
23 36405589 D405N
S
S
COVID-19
G
R
S
C
L
View
24 36405589 A67V
S
S
COVID-19
G
R
S
C
L
View
25 36405589 214insEPE
S
S
COVID-19
G
R
S
C
L
View
26 36405589 S371L
S
S
COVID-19
G
R
S
C
L
View
27 36405589 G446S
S
S
COVID-19
G
R
S
C
L
View
28 36405589 G496S
S
S
COVID-19
G
R
S
C
L
View
29 36405589 T547K
S
S
COVID-19
G
R
S
C
L
View
30 36405589 N856K
S
S
COVID-19
G
R
S
C
L
View
31 36405589 L981F
S
S
COVID-19
G
R
S
C
L
View
32 36405589 T95I
S
S
COVID-19
G
R
S
C
L
View
33 36405589 G339D
S
S
COVID-19
G
R
S
C
L
View
34 36405589 S373P
S
S
COVID-19
G
R
S
C
L
View
35 36405589 S375F
S
S
COVID-19
G
R
S
C
L
View
36 36405589 K417N
S
S
COVID-19
G
R
S
C
L
View
37 36405589 S477N
S
S
COVID-19
G
R
S
C
L
View
38 36405589 E484A
S
S
COVID-19
G
R
S
C
L
View
39 36405589 Q493R
S
S
COVID-19
G
R
S
C
L
View
40 36405589 Q498R
S
S
COVID-19
G
R
S
C
L
View
41 36405589 N501Y
S
S
COVID-19
G
R
S
C
L
View
42 36405589 Y505H
S
S
COVID-19
G
R
S
C
L
View
43 36405589 N679K
S
S
COVID-19
G
R
S
C
L
View
44 36405589 P681H
S
S
COVID-19
G
R
S
C
L
View
45 36405589 H655Y
S
S
COVID-19
G
R
S
C
L
View
46 36405589 N764K
S
S
COVID-19
G
R
S
C
L
View
47 36405589 D796Y
S
S
COVID-19
G
R
S
C
L
View
48 36405589 Q954H
S
S
COVID-19
G
R
S
C
L
View
49 36405589 N969K
S
S
COVID-19
G
R
S
C
L
View
50 36405589 T478K
S
S
COVID-19
G
R
S
C
L
View
51 36405589 D614G
S
S
COVID-19
G
R
S
C
L
View
52 36405589 R346K
S
S
COVID-19
G
R
S
C
L
View
53 36405589 L730F COVID-19
G
R
S
C
L
View
54 36405589 N440K
S
S
COVID-19
G
R
S
C
L
View
55 36405589 K477N
S
S
COVID-19
R
S
C
L
View
56 36405589 T223I
ORF3a
ORF3a
COVID-19
R
S
C
L
View
57 36405589 A2710T
ORF1ab
ORF1ab
COVID-19
R
S
C
L
View
58 36405589 I3758V
ORF1ab
ORF1ab
COVID-19
R
S
C
L
View
59 36405589 I5967V
ORF1ab
ORF1ab
COVID-19
R
S
C
L
View
60 36405589 K856R
ORF1ab
ORF1ab
COVID-19
R
S
C
L
View
61 36405589 S2083I
ORF1ab
ORF1ab
COVID-19
R
S
C
L
View
62 36405589 S5360P
ORF1ab
ORF1ab
COVID-19
R
S
C
L
View
63 36405589 P13L
N
N
COVID-19
R
S
C
L
View
64 36405589 R203K
N
N
COVID-19
R
S
C
L
View
65 36405589 S413R
N
N
COVID-19
R
S
C
L
View
66 36405589 L24S
S
S
COVID-19
G
R
S
C
L
View
67 36405589 S704L
S
S
COVID-19
G
R
S
C
L
View
68 36405589 G75R
S
S
COVID-19
G
R
S
C
L
View
69 36405589 N165K
S
S
COVID-19
G
R
S
C
L
View
70 36405589 F643L
S
S
COVID-19
G
R
S
C
L
View
71 36405589 Q19E
M
M
COVID-19
R
S
C
L
View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.