All Curated Mutation Sites in SARS-CoV-2

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The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.

Browse Data by Virus Gene/Protein/Region, Disease OR Description

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Virus Gene/Protein

Disease

Description

For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

Furin cleavage site

Methyltransferase

Non-coding region

Keyword: COVID-19-36409737

ID	PMID	Mutation	Gene/Protein/Region	Encoding Gene/Protein	Disease	Description	Detail
1	36409737	A145D	PLpro	ORF1a	COVID-19		View
2	36409737	G163C	PLpro	ORF1a	COVID-19		View
3	36409737	A246T	PLpro	ORF1a	COVID-19		View
4	36409737	E161A	PLpro	ORF1a	COVID-19		View
5	36409737	T291I	PLpro	ORF1a	COVID-19		View
6	36409737	E161D	PLpro	ORF1a	COVID-19		View
7	36409737	P247S	PLpro	ORF1a	COVID-19		View
8	36409737	E161G	PLpro	ORF1a	COVID-19		View
9	36409737	L162S	PLpro	ORF1a	COVID-19		View
10	36409737	G163S	PLpro	ORF1a	COVID-19		View
11	36409737	V165I	PLpro	ORF1a	COVID-19		View
12	36409737	A246V	PLpro	ORF1a	COVID-19		View
13	36409737	P247L	PLpro	ORF1a	COVID-19		View
14	36409737	P247Q	PLpro	ORF1a	COVID-19		View
15	36409737	P247T	PLpro	ORF1a	COVID-19		View
16	36409737	P248S	PLpro	ORF1a	COVID-19		View
17	36409737	E263D	PLpro	ORF1a	COVID-19		View
18	36409737	Y264H	PLpro	ORF1a	COVID-19		View
19	36409737	T265A	PLpro	ORF1a	COVID-19		View
20	36409737	Y268C	PLpro	ORF1a	COVID-19		View
21	36409737	N267D	PLpro	ORF1a	COVID-19		View
22	36409737	N267S	PLpro	ORF1a	COVID-19		View
23	36409737	Y268H	PLpro	ORF1a	COVID-19		View
24	36409737	Q269K	PLpro	ORF1a	COVID-19		View
25	36409737	T277I	PLpro	ORF1a	COVID-19		View
26	36409737	Q269R	PLpro	ORF1a	COVID-19		View
27	36409737	T301A	PLpro	ORF1a	COVID-19		View
28	36409737	T301S	PLpro	ORF1a	COVID-19		View

Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note

D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.

G
The study mentioned the virus genotype/subtype information.

R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.

S
The study provided sequence information or accession numbers.

L
The study provided the geographic region/country of data origin.

C
The study provided clinical baseline information.

I
The study involved information related to immune.

T
The study involved host target genes.