All Curated Mutation Sites in SARS-CoV-2 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: COVID-19-36465857
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 36465857 L18F
S
S
COVID-19
G
View
2 36465857 T20N
S
S
COVID-19
G
View
3 36465857 P26S
S
S
COVID-19
G
View
4 36465857 D138Y
S
S
COVID-19
G
View
5 36465857 R190S
S
S
COVID-19
G
View
6 36465857 K417T
S
S
COVID-19
G
View
7 36465857 H655Y
S
S
COVID-19
G
View
8 36465857 T1027I
S
S
COVID-19
G
View
9 36465857 V1176F
S
S
COVID-19
G
View
10 36465857 T19R
S
S
COVID-19
G
View
11 36465857 G142D
S
S
COVID-19
G
View
12 36465857 156del
S
S
COVID-19
G
View
13 36465857 157del
S
S
COVID-19
G
View
14 36465857 R158G
S
S
COVID-19
G
View
15 36465857 L452R
S
S
COVID-19
G
View
16 36465857 T478K
S
S
COVID-19
G
View
17 36465857 P681R
S
S
COVID-19
G
View
18 36465857 D614G
S
S
COVID-19
G
View
19 36465857 E484K
S
S
COVID-19
G
View
20 36465857 N501Y
S
S
COVID-19
G
View
21 36465857 D80A
S
S
COVID-19
G
View
22 36465857 D215G
S
S
COVID-19
G
View
23 36465857 242del
S
S
COVID-19
G
View
24 36465857 243del
S
S
COVID-19
G
View
25 36465857 244del
S
S
COVID-19
G
View
26 36465857 K417N
S
S
COVID-19
G
View
27 36465857 A701V
S
S
COVID-19
G
View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.