All Curated Mutation Sites in SARS-CoV-2 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: COVID-19-36474565
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 36474565 A222V
S
S
COVID-19
R
View
2 36474565 L18F
S
S
COVID-19
R
View
3 36474565 D614G
S
S
COVID-19
R
View
4 36474565 M153T
S
S
COVID-19
R
View
5 36474565 N501Y
S
S
COVID-19
R
View
6 36474565 E484K
S
S
COVID-19
R
View
7 36474565 P681R
S
S
COVID-19
R
View
8 36474565 D138Y
S
S
COVID-19
R
View
9 36474565 D950N
S
S
COVID-19
R
View
10 36474565 V16I
S
S
COVID-19
R
View
11 36474565 W152L
S
S
COVID-19
R
View
12 36474565 T478K
S
S
COVID-19
R
View
13 36474565 N439K
S
S
COVID-19
R
View
14 36474565 Q675H
S
S
COVID-19
R
View
15 36474565 V382L
S
S
COVID-19
R
View
16 36474565 G769V
S
S
COVID-19
R
View
17 36474565 L452R
S
S
COVID-19
R
View
18 36474565 S12F
S
S
COVID-19
R
View
19 36474565 S477N
S
S
COVID-19
R
View
20 36474565 T19R
S
S
COVID-19
R
View
21 36474565 T385I
S
S
COVID-19
R
View
22 36474565 A701V
S
S
COVID-19
R
View
23 36474565 A845S
S
S
COVID-19
R
View
24 36474565 Q677H
S
S
COVID-19
R
View
25 36474565 G142D
S
S
COVID-19
R
View
26 36474565 A522S
S
S
COVID-19
R
View
27 36474565 Q321L
S
S
COVID-19
R
View
28 36474565 I720V
S
S
COVID-19
R
View
29 36474565 E484A
S
S
COVID-19
R
View
30 36474565 P681H
S
S
COVID-19
R
View
31 36474565 N679K
S
S
COVID-19
R
View
32 36474565 L54F
S
S
COVID-19
R
View
33 36474565 N440K
S
S
COVID-19
R
View
34 36474565 T95I
S
S
COVID-19
R
View
35 36474565 E780G
S
S
COVID-19
R
View
36 36474565 K417N
S
S
COVID-19
R
View
37 36474565 S940F
S
S
COVID-19
R
View
38 36474565 L5F
S
S
COVID-19
R
View
39 36474565 G1251V
S
S
COVID-19
R
View
40 36474565 D3Y
N
N
COVID-19
R
View
41 36474565 R203M
N
N
COVID-19
R
View
42 36474565 D377Y
N
N
COVID-19
R
View
43 36474565 D63G
N
N
COVID-19
R
View
44 36474565 G215C
N
N
COVID-19
R
View
45 36474565 G204R
N
N
COVID-19
R
View
46 36474565 A211V
N
N
COVID-19
R
View
47 36474565 D3L
N
N
COVID-19
R
View
48 36474565 S194L
N
N
COVID-19
R
View
49 36474565 T205I
N
N
COVID-19
R
View
50 36474565 M234I
N
N
COVID-19
R
View
51 36474565 S235F
N
N
COVID-19
R
View
52 36474565 P13L
N
N
COVID-19
R
View
53 36474565 R385K
N
N
COVID-19
R
View
54 36474565 Q9L
N
N
COVID-19
R
View
55 36474565 A211S
N
N
COVID-19
R
View
56 36474565 P151L
N
N
COVID-19
R
View
57 36474565 S413R
N
N
COVID-19
R
View
58 36474565 G212C
N
N
COVID-19
R
View
59 36474565 S197L
N
N
COVID-19
R
View
60 36474565 Q418H
N
N
COVID-19
R
View
61 36474565 L139F
N
N
COVID-19
R
View
62 36474565 I82T
M
M
COVID-19
R
View
63 36474565 A63T
M
M
COVID-19
R
View
64 36474565 F100I
M
M
COVID-19
R
View
65 36474565 Q19E
M
M
COVID-19
R
View
66 36474565 D3G
M
M
COVID-19
R
View
67 36474565 A2V
M
M
COVID-19
R
View
68 36474565 L16I
M
M
COVID-19
R
View
69 36474565 F28L
M
M
COVID-19
R
View
70 36474565 H155Y
M
M
COVID-19
R
View
71 36474565 V70I
M
M
COVID-19
R
View
72 36474565 S214I
M
M
COVID-19
R
View
73 36474565 L34F
M
M
COVID-19
R
View
74 36474565 I201V
M
M
COVID-19
R
View
75 36474565 H125Y
M
M
COVID-19
R
View
76 36474565 A69S
M
M
COVID-19
R
View
77 36474565 T30I
M
M
COVID-19
R
View
78 36474565 V70F
M
M
COVID-19
R
View
79 36474565 M1I
M
M
COVID-19
R
View
80 36474565 S4F
M
M
COVID-19
R
View
81 36474565 D209Y
M
M
COVID-19
R
View
82 36474565 E167D
M
M
COVID-19
R
View
83 36474565 M109I
M
M
COVID-19
R
View
84 36474565 L29F
M
M
COVID-19
R
View
85 36474565 T208I
M
M
COVID-19
R
View
86 36474565 A81S
M
M
COVID-19
R
View
87 36474565 G6V
M
M
COVID-19
R
View
88 36474565 A40S
M
M
COVID-19
R
View
89 36474565 T9I
E
E
COVID-19
R
View
90 36474565 E8D
E
E
COVID-19
R
View
91 36474565 P71L
E
E
COVID-19
R
View
92 36474565 S55F
E
E
COVID-19
R
View
93 36474565 V62F
E
E
COVID-19
R
View
94 36474565 L21F
E
E
COVID-19
R
View
95 36474565 V58F
E
E
COVID-19
R
View
96 36474565 S68F
E
E
COVID-19
R
View
97 36474565 L73F
E
E
COVID-19
R
View
98 36474565 S16G
E
E
COVID-19
R
View
99 36474565 V70F
E
E
COVID-19
R
View
100 36474565 V24A
E
E
COVID-19
R
View
101 36474565 V49L
E
E
COVID-19
R
View
102 36474565 R69I
E
E
COVID-19
R
View
103 36474565 A41V
E
E
COVID-19
R
View
104 36474565 D72G
E
E
COVID-19
R
View
105 36474565 N66S
E
E
COVID-19
R
View
106 36474565 R61L
E
E
COVID-19
R
View
107 36474565 S50I
E
E
COVID-19
R
View
108 36474565 T30I
E
E
COVID-19
R
View
109 36474565 F23L
E
E
COVID-19
R
View
110 36474565 V75L
E
E
COVID-19
R
View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.