All Curated Mutation Sites in SARS-CoV-2 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: COVID-19-36535326
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 36535326 144delY
NTD
S
COVID-19
G
S
View
2 36535326 R346T
RBD
S
COVID-19
G
S
View
3 36535326 R346S
RBD
S
COVID-19
G
S
View
4 36535326 K356T
RBD
S
COVID-19
G
S
View
5 36535326 N417Y
RBD
S
COVID-19
G
S
View
6 36535326 N417H
RBD
S
COVID-19
G
S
View
7 36535326 N417I
RBD
S
COVID-19
G
S
View
8 36535326 N417T
RBD
S
COVID-19
G
S
View
9 36535326 K444E
RBD
S
COVID-19
G
S
View
10 36535326 K444Q
RBD
S
COVID-19
G
S
View
11 36535326 K444N
RBD
S
COVID-19
G
S
View
12 36535326 K444T
RBD
S
COVID-19
G
S
View
13 36535326 K444M
RBD
S
COVID-19
G
S
View
14 36535326 V445D
RBD
S
COVID-19
G
S
View
15 36535326 V445G
RBD
S
COVID-19
G
S
View
16 36535326 V445A
RBD
S
COVID-19
G
S
View
17 36535326 N450T
RBD
S
COVID-19
G
S
View
18 36535326 N450D
RBD
S
COVID-19
G
S
View
19 36535326 N450K
RBD
S
COVID-19
G
S
View
20 36535326 N450S
RBD
S
COVID-19
G
S
View
21 36535326 L452R
RBD
S
COVID-19
G
S
View
22 36535326 I468N
RBD
S
COVID-19
G
S
View
23 36535326 A484P
RBD
S
COVID-19
G
S
View
24 36535326 F486S
RBD
S
COVID-19
G
S
View
25 36535326 F486V
RBD
S
COVID-19
G
S
View
26 36535326 F490S
RBD
S
COVID-19
G
S
View
27 36535326 F490Y
RBD
S
COVID-19
G
S
View
28 36535326 V83A
RBD
S
COVID-19
S
I
View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.