All Curated Mutation Sites in SARS-CoV-2 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: COVID-19-36560780
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 36560780 G946V
S
S
COVID-19
View
2 36560780 C1243F
S
S
COVID-19
View
3 36560780 T307I
S
S
COVID-19
View
4 36560780 E583D
S
S
COVID-19
View
5 36560780 A647S
S
S
COVID-19
View
6 36560780 R683Q
S
S
COVID-19
View
7 36560780 H655Y
S
S
COVID-19
View
8 36560780 P681H
S
S
COVID-19
View
9 36560780 V1104L
S
S
COVID-19
View
10 36560780 A684V
S
S
COVID-19
View
11 36560780 D614G
S
S
COVID-19
View
12 36560780 L84S
ORF8
ORF8
COVID-19
View
13 36560780 Q57H
ORF3a
ORF3a
COVID-19
View
14 36560780 P314L
ORF1b
ORF1b
COVID-19
View
15 36560780 Y1464C
ORF1b
ORF1b
COVID-19
View
16 36560780 P1427L
ORF1b
ORF1b
COVID-19
View
17 36560780 T265I
ORF1a
ORF1a
COVID-19
View
18 36560780 L176F
NTD
S
COVID-19
View
19 36560780 P323L
NSP12
ORF1b
COVID-19
View
20 36560780 S183Y
N
N
COVID-19
View
21 36560780 S194L
N
N
COVID-19
View
22 36560780 G204R
N
N
COVID-19
View
23 36560780 N203R
N
N
COVID-19
View
24 36560780 P71L
E
E
COVID-19
View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.