All Curated Mutation Sites in SARS-CoV-2 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: COVID-19-36590492
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 36590492 N501Y
S
S
COVID-19
G
R
S
L
View
2 36590492 T19R
S
S
COVID-19
G
R
S
L
View
3 36590492 P26S
S
S
COVID-19
G
R
S
L
View
4 36590492 L54F
S
S
COVID-19
G
R
S
L
View
5 36590492 T95I
S
S
COVID-19
G
R
S
L
View
6 36590492 G142D
S
S
COVID-19
G
R
S
L
View
7 36590492 E156G
S
S
COVID-19
G
R
S
L
View
8 36590492 157delF
S
S
COVID-19
G
R
S
L
View
9 36590492 158delR
S
S
COVID-19
G
R
S
L
View
10 36590492 L452R
S
S
COVID-19
G
R
S
L
View
11 36590492 T478K
S
S
COVID-19
G
R
S
L
View
12 36590492 D614G
S
S
COVID-19
G
R
S
L
View
13 36590492 P681R
S
S
COVID-19
G
R
S
L
View
14 36590492 D950N
S
S
COVID-19
G
R
S
L
View
15 36590492 T77A
NSP6
ORF1a
COVID-19
G
R
S
L
View
16 36590492 V167L
NSP4
ORF1a
COVID-19
G
R
S
L
View
17 36590492 T492I
NSP4
ORF1a
COVID-19
G
R
S
L
View
18 36590492 A488S
NSP3
ORF1a
COVID-19
G
R
S
L
View
19 36590492 P1228L
NSP3
ORF1a
COVID-19
G
R
S
L
View
20 36590492 P1469S
NSP3
ORF1a
COVID-19
G
R
S
L
View
21 36590492 L1511V
NSP3
ORF1a
COVID-19
G
R
S
L
View
22 36590492 A1711V
NSP3
ORF1a
COVID-19
G
R
S
L
View
23 36590492 P1867T
NSP3
ORF1a
COVID-19
G
R
S
L
View
24 36590492 A394V
NSP14
ORF1b
COVID-19
G
R
S
L
View
25 36590492 P77L
NSP13
ORF1b
COVID-19
G
R
S
L
View
26 36590492 P323L
NSP12
ORF1b
COVID-19
G
R
S
L
View
27 36590492 G671S
NSP12
ORF1b
COVID-19
G
R
S
L
View
28 36590492 S100C
NSP1
ORF1a
COVID-19
G
R
S
L
View
29 36590492 T40I
NS7b
ORF7b
COVID-19
G
R
S
L
View
30 36590492 V82A
NS7a
ORF7a
COVID-19
G
R
S
L
View
31 36590492 T120I
NS7a
ORF7a
COVID-19
G
R
S
L
View
32 36590492 S26L
NS3
ORF3a
COVID-19
G
R
S
L
View
33 36590492 D63G
N
N
COVID-19
G
R
S
L
View
34 36590492 R203M
N
N
COVID-19
G
R
S
L
View
35 36590492 G215C
N
N
COVID-19
G
R
S
L
View
36 36590492 D377Y
N
N
COVID-19
G
R
S
L
View
37 36590492 I82T
M
M
COVID-19
G
R
S
L
View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.