All Curated Mutation Sites in SARS-CoV-2 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

Show All
  
ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: COVID-19-36672914
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 36672914 T478K
S
S
COVID-19
G
C
L
View
2 36672914 K417N
S
S
COVID-19
G
C
L
View
3 36672914 Y505H
S
S
COVID-19
I
C
L
View
4 36672914 T95A
S
S
COVID-19
C
L
View
5 36672914 T547K
S
S
COVID-19
C
L
View
6 36672914 S477N
S
S
COVID-19
I
C
L
View
7 36672914 S375F
S
S
COVID-19
C
L
View
8 36672914 S373P
S
S
COVID-19
C
L
View
9 36672914 S371L
S
S
COVID-19
C
L
View
10 36672914 Q954H
S
S
COVID-19
C
L
View
11 36672914 Q493R
S
S
COVID-19
I
C
L
View
12 36672914 P681H
S
S
COVID-19
I
C
L
View
13 36672914 N969K
S
S
COVID-19
C
L
View
14 36672914 N856K
S
S
COVID-19
I
C
L
View
15 36672914 N764K
S
S
COVID-19
I
C
L
View
16 36672914 N679K
S
S
COVID-19
C
L
View
17 36672914 N501Y
S
S
COVID-19
I
C
L
View
18 36672914 N440K
S
S
COVID-19
I
C
L
View
19 36672914 L981F
S
S
COVID-19
I
C
L
View
20 36672914 L212I
S
S
COVID-19
C
L
View
21 36672914 H655Y
S
S
COVID-19
C
L
View
22 36672914 G496S
S
S
COVID-19
I
C
L
View
23 36672914 G446S
S
S
COVID-19
I
C
L
View
24 36672914 G339D
S
S
COVID-19
C
L
View
25 36672914 G142D
S
S
COVID-19
C
L
View
26 36672914 E484A
S
S
COVID-19
I
C
L
View
27 36672914 D796Y
S
S
COVID-19
I
C
L
View
28 36672914 D614G
S
S
COVID-19
C
L
View
29 36672914 A67V
S
S
COVID-19
C
L
View
30 36672914 R203K
N
N
COVID-19
C
L
View
31 36672914 P13L
N
N
COVID-19
C
L
View
32 36672914 G204R
N
N
COVID-19
C
L
View
33 36672914 Y234H
NSP6
ORF1a
COVID-19
C
L
View
34 36672914 Q208R
NSP6
ORF1a
COVID-19
C
L
View
35 36672914 I189V
NSP6
ORF1a
COVID-19
C
L
View
36 36672914 P132H
NSP5
ORF1a
COVID-19
C
L
View
37 36672914 T492I
NSP4
ORF1a
COVID-19
C
L
View
38 36672914 L1266I
NSP3
ORF1a
COVID-19
C
L
View
39 36672914 A1892T
NSP3
ORF1a
COVID-19
C
L
View
40 36672914 P323L
NSP12
ORF1b
COVID-19
C
L
View
41 36672914 F283S
NSP12
ORF1b
COVID-19
C
L
View
42 36672914 Q19E
M
M
COVID-19
C
L
View
43 36672914 D3G
M
M
COVID-19
C
L
View
44 36672914 A63T
M
M
COVID-19
C
L
View
45 36672914 T9I
E
E
COVID-19
C
L
View
46 36672914 M87Y COVID-19
C
L
View
47 36672914 L260P COVID-19
C
L
View
48 36672914 K384R COVID-19
C
L
View
49 36672914 I42V COVID-19
C
L
View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.