All Curated Mutation Sites in SARS-CoV-2 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: COVID-19-36687433
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 36687433 T19R
S
S
COVID-19
G
R
S
L
View
2 36687433 L452R
S
S
COVID-19
G
R
S
L
View
3 36687433 T478K
S
S
COVID-19
G
R
S
L
View
4 36687433 P681R
S
S
COVID-19
G
R
S
L
View
5 36687433 D950N
S
S
COVID-19
G
R
S
L
View
6 36687433 V82A
ORF7a
ORF7a
COVID-19
G
R
S
L
View
7 36687433 T120I
ORF7a
ORF7a
COVID-19
G
R
S
L
View
8 36687433 S26L
ORF3a
ORF3a
COVID-19
G
R
S
L
View
9 36687433 D63G
N
N
COVID-19
G
R
S
L
View
10 36687433 R203M
N
N
COVID-19
G
R
S
L
View
11 36687433 D377Y
N
N
COVID-19
G
R
S
L
View
12 36687433 I82T
M
M
COVID-19
G
R
S
L
View
13 36687433 D80A
S
S
COVID-19
G
R
S
L
View
14 36687433 D215G
S
S
COVID-19
G
R
S
L
View
15 36687433 K417N
S
S
COVID-19
G
R
S
L
View
16 36687433 Q57H
ORF3a
ORF3a
COVID-19
G
R
S
L
View
17 36687433 P71L
E
E
COVID-19
G
R
S
L
View
18 36687433 T22I
S
S
COVID-19
G
R
S
L
View
19 36687433 N164H
S
S
COVID-19
G
R
S
L
View
20 36687433 A99S
ORF3a
ORF3a
COVID-19
G
R
S
L
View
21 36687433 S434G
NSP14
ORF1b
COVID-19
G
R
S
L
View
22 36687433 M233I
NSP13
ORF1b
COVID-19
G
R
S
L
View
23 36687433 L18F
S
S
COVID-19
G
R
S
L
View
24 36687433 N501Y
S
S
COVID-19
G
R
S
L
View
25 36687433 P13S
S
S
COVID-19
G
R
S
L
View
26 36687433 S171L
ORF3a
ORF3a
COVID-19
G
R
S
L
View
27 36687433 P4715L
ORF1ab
ORF1ab
COVID-19
R
S
L
View
28 36687433 Q191R
NSP3
ORF1a
COVID-19
R
S
L
View
29 36687433 P323L
NSP12
ORF1b
COVID-19
R
S
L
View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.