All Curated Mutation Sites in SARS-CoV-2 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: COVID-19-36733340
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 36733340 H49Y
S
S
COVID-19
R
L
View
2 36733340 L54F
S
S
COVID-19
R
L
View
3 36733340 N74K
S
S
COVID-19
R
L
View
4 36733340 D80Y
S
S
COVID-19
R
L
View
5 36733340 G142A
S
S
COVID-19
R
L
View
6 36733340 A222V
S
S
COVID-19
R
L
View
7 36733340 G261R
S
S
COVID-19
R
L
View
8 36733340 S943T
S
S
COVID-19
R
L
View
9 36733340 D614G
S
S
COVID-19
R
L
View
10 36733340 D614A
S
S
COVID-19
R
L
View
11 36733340 V622F
S
S
COVID-19
R
L
View
12 36733340 Q677H
S
S
COVID-19
R
L
View
13 36733340 S813N
S
S
COVID-19
R
L
View
14 36733340 A890T
S
S
COVID-19
R
L
View
15 36733340 A1078S
S
S
COVID-19
R
L
View
16 36733340 T1117I
S
S
COVID-19
R
L
View
17 36733340 C840V
S
S
COVID-19
R
L
View
18 36733340 A846V
S
S
COVID-19
R
L
View
19 36733340 G446V
RBD
S
COVID-19
R
L
View
20 36733340 G181V
NTD
S
COVID-19
R
L
View
21 36733340 R102S
NTD
S
COVID-19
R
L
View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.