All Curated Mutation Sites in SARS-CoV-2 
Back to Mutation Home

 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

Show All
  
ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: COVID-19-36755883
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 36755883 D796K
S
S
COVID-19
G
R
L
View
2 36755883 Q954H
S
S
COVID-19
G
R
L
View
3 36755883 S84L
ORF8
ORF8
COVID-19
G
R
L
View
4 36755883 D61L
ORF6
ORF6
COVID-19
G
R
L
View
5 36755883 P314L
ORF1b
ORF1b
COVID-19
G
R
L
View
6 36755883 G662S
ORF1b
ORF1b
COVID-19
G
R
L
View
7 36755883 R1315C
ORF1b
ORF1b
COVID-19
G
R
L
View
8 36755883 I1566V
ORF1b
ORF1b
COVID-19
G
R
L
View
9 36755883 T2163I
ORF1b
ORF1b
COVID-19
G
R
L
View
10 36755883 S135R
ORF1a
ORF1a
COVID-19
G
R
L
View
11 36755883 T842I
ORF1a
ORF1a
COVID-19
G
R
L
View
12 36755883 G1307L
ORF1a
ORF1a
COVID-19
G
R
L
View
13 36755883 L3027F
ORF1a
ORF1a
COVID-19
G
R
L
View
14 36755883 T3090I
ORF1a
ORF1a
COVID-19
G
R
L
View
15 36755883 T3255I
ORF1a
ORF1a
COVID-19
G
R
L
View
16 36755883 P3395H
ORF1a
ORF1a
COVID-19
G
R
L
View
17 36755883 P13L
N
N
COVID-19
G
R
L
View
18 36755883 R203K
N
N
COVID-19
G
R
L
View
19 36755883 G204R
N
N
COVID-19
G
R
L
View
20 36755883 S413R
N
N
COVID-19
G
R
L
View
21 36755883 Q19E
M
M
COVID-19
G
R
L
View
22 36755883 A63T
M
M
COVID-19
G
R
L
View
23 36755883 T9I
E
E
COVID-19
G
R
L
View
24 36755883 T11A
E
E
COVID-19
G
R
L
View
25 36755883 N4060S
ORF1a
ORF1a
COVID-19
G
R
L
View
26 36755883 Q4060S COVID-19
G
R
L
View
27 36755883 T223I
ORF3a
ORF3a
COVID-19
G
R
L
View
28 36755883 P240S
ORF3
ORF3a
COVID-19
G
R
L
View
29 36755883 P1640S
ORF1a
ORF1a
COVID-19
G
R
L
View
30 36755883 S1221L
ORF1a
ORF1a
COVID-19
G
R
L
View
31 36755883 D3N
M
M
COVID-19
G
R
L
View
32 36755883 E1202Q
S
S
COVID-19
G
R
L
View
33 36755883 T19I
S
S
COVID-19
G
R
L
View
34 36755883 L24S
S
S
COVID-19
G
R
L
View
35 36755883 25_27del
S
S
COVID-19
G
R
L
View
36 36755883 69_70del
S
S
COVID-19
G
R
L
View
37 36755883 G142D
S
S
COVID-19
G
R
L
View
38 36755883 V213G
S
S
COVID-19
G
R
L
View
39 36755883 G339D
S
S
COVID-19
G
R
L
View
40 36755883 S371F
S
S
COVID-19
G
R
L
View
41 36755883 S373P
S
S
COVID-19
G
R
L
View
42 36755883 S375F
S
S
COVID-19
G
R
L
View
43 36755883 T376A
S
S
COVID-19
G
R
L
View
44 36755883 D405N
S
S
COVID-19
G
R
L
View
45 36755883 R408S
S
S
COVID-19
G
R
L
View
46 36755883 G446S
S
S
COVID-19
G
R
L
View
47 36755883 S477N
S
S
COVID-19
G
R
L
View
48 36755883 T478K
S
S
COVID-19
G
R
L
View
49 36755883 E484A
S
S
COVID-19
G
R
L
View
50 36755883 Q493R
S
S
COVID-19
G
R
L
View
51 36755883 L452R
S
S
COVID-19
G
R
L
View
52 36755883 K417N
S
S
COVID-19
G
R
L
View
53 36755883 N440K
S
S
COVID-19
G
R
L
View
54 36755883 Q498R
S
S
COVID-19
G
R
L
View
55 36755883 D614G
S
S
COVID-19
G
R
L
View
56 36755883 H655Y
S
S
COVID-19
G
R
L
View
57 36755883 N679K
S
S
COVID-19
G
R
L
View
58 36755883 P681H
S
S
COVID-19
G
R
L
View
59 36755883 N764K
S
S
COVID-19
G
R
L
View
60 36755883 D796Y
S
S
COVID-19
G
R
L
View
61 36755883 N954H
S
S
COVID-19
G
R
L
View
62 36755883 N969K
S
S
COVID-19
G
R
L
View
63 36755883 N501Y
S
S
COVID-19
G
R
L
View
64 36755883 Y505H
S
S
COVID-19
G
R
L
View
65 36755883 K147E
S
S
COVID-19
G
R
L
View
66 36755883 W152R
S
S
COVID-19
G
R
L
View
67 36755883 F157L
S
S
COVID-19
G
R
L
View
68 36755883 I210V
S
S
COVID-19
G
R
L
View
69 36755883 Y248N
S
S
COVID-19
G
R
L
View
70 36755883 G257S
S
S
COVID-19
G
R
L
View
71 36755883 G339H
S
S
COVID-19
G
R
L
View
72 36755883 R346T
S
S
COVID-19
G
R
L
View
73 36755883 S371Y
S
S
COVID-19
G
R
L
View
74 36755883 K417T
S
S
COVID-19
G
R
L
View
75 36755883 L452M
S
S
COVID-19
G
R
L
View
76 36755883 N460K
S
S
COVID-19
G
R
L
View
77 36755883 T1050N
ORF1b
ORF1b
COVID-19
G
R
L
View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.