All Curated Mutation Sites in SARS-CoV-2 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: COVID-19-36786950
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 36786950 G75V
S
S
COVID-19
G
R
S
View
2 36786950 T76I
S
S
COVID-19
G
R
S
View
3 36786950 L452Q
S
S
COVID-19
G
R
S
View
4 36786950 F490S
S
S
COVID-19
G
R
S
View
5 36786950 D614G
S
S
COVID-19
G
R
S
View
6 36786950 T859N
S
S
COVID-19
G
R
S
View
7 36786950 246_253del
S
S
COVID-19
G
R
S
View
8 36786950 P313L
ORF1b
ORF1b
COVID-19
G
R
S
C
L
View
9 36786950 T1246I
ORF1ab
ORF1ab
COVID-19
G
R
S
View
10 36786950 P2287S
ORF1ab
ORF1ab
COVID-19
G
R
S
View
11 36786950 F2387V
ORF1ab
ORF1ab
COVID-19
G
R
S
View
12 36786950 L3201P
ORF1ab
ORF1ab
COVID-19
G
R
S
View
13 36786950 T3255I
ORF1ab
ORF1ab
COVID-19
G
R
S
View
14 36786950 G3278S
ORF1ab
ORF1ab
COVID-19
G
R
S
View
15 36786950 3675_3677del
ORF1ab
ORF1ab
COVID-19
G
R
S
View
16 36786950 P13L
N
N
COVID-19
G
R
S
C
L
View
17 36786950 G214C
N
N
COVID-19
G
R
S
View
18 36786950 F1469S
NSP3
ORF1a
COVID-19
G
R
S
C
L
View
19 36786950 F1569V
NSP3
ORF1a
COVID-19
G
R
S
C
L
View
20 36786950 T248I
NSP3
ORF1a
COVID-19
G
R
S
C
L
View
21 36786950 P37L
N
N
COVID-19
G
R
S
C
L
View
22 36786950 L18F
S
S
COVID-19
G
R
S
C
L
View
23 36786950 R346K
S
S
COVID-19
G
R
S
View
24 36786950 S373P
S
S
COVID-19
G
R
S
C
L
View
25 36786950 G1167A
S
S
COVID-19
G
R
S
C
L
View
26 36786950 S84L
ORF8
ORF8
COVID-19
G
R
S
C
L
View
27 36786950 L1175F
ORF1a
ORF1a
COVID-19
G
R
S
View
28 36786950 V3718F
ORF1a
ORF1a
COVID-19
G
R
S
View
29 36786950 P314L
ORF1a
ORF1a
COVID-19
G
R
S
View
30 36786950 S2Y
N
N
COVID-19
G
R
S
C
L
View
31 36786950 R203K
N
N
COVID-19
G
R
S
C
L
View
32 36786950 G204R
N
N
COVID-19
G
R
S
View
33 36786950 F101Y
ORF7a
ORF7a
COVID-19
R
S
C
L
View
34 36786950 E419A
NSP3
ORF1a
COVID-19
R
S
C
L
View
35 36786950 T223I
NSP2
ORF1a
COVID-19
R
S
C
L
View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.