All Curated Mutation Sites in SARS-CoV-2 
Back to Mutation Home

 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

Show All
  
ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: COVID-19-36819024
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 36819024 A67V
S
S
COVID-19
G
L
View
2 36819024 69delH
S
S
COVID-19
G
L
View
3 36819024 70delV
S
S
COVID-19
G
L
View
4 36819024 T95I
S
S
COVID-19
G
L
View
5 36819024 142delG
S
S
COVID-19
G
L
View
6 36819024 Y145D
S
S
COVID-19
G
L
View
7 36819024 G339D
S
S
COVID-19
G
L
View
8 36819024 R346K
S
S
COVID-19
G
L
View
9 36819024 S371L
S
S
COVID-19
G
L
View
10 36819024 S373P
S
S
COVID-19
G
L
View
11 36819024 S375F
S
S
COVID-19
G
L
View
12 36819024 K417N
S
S
COVID-19
G
L
View
13 36819024 N440K
S
S
COVID-19
G
L
View
14 36819024 G446S
S
S
COVID-19
G
L
View
15 36819024 S477N
S
S
COVID-19
G
L
View
16 36819024 E484A
S
S
COVID-19
G
L
View
17 36819024 Q493R
S
S
COVID-19
G
L
View
18 36819024 G496S
S
S
COVID-19
G
L
View
19 36819024 Q498R
S
S
COVID-19
G
L
View
20 36819024 N501Y
S
S
COVID-19
G
L
View
21 36819024 Y505H
S
S
COVID-19
G
L
View
22 36819024 T547K
S
S
COVID-19
G
L
View
23 36819024 H655Y
S
S
COVID-19
G
L
View
24 36819024 N679K
S
S
COVID-19
G
L
View
25 36819024 P681H
S
S
COVID-19
G
L
View
26 36819024 N764K
S
S
COVID-19
G
L
View
27 36819024 D796Y
S
S
COVID-19
G
L
View
28 36819024 N856K
S
S
COVID-19
G
L
View
29 36819024 Q954H
S
S
COVID-19
G
L
View
30 36819024 N969K
S
S
COVID-19
G
L
View
31 36819024 L981F
S
S
COVID-19
G
L
View
32 36819024 G142D
S
S
COVID-19
G
L
View
33 36819024 143delV
S
S
COVID-19
G
L
View
34 36819024 144delY
S
S
COVID-19
G
L
View
35 36819024 145delY
S
S
COVID-19
G
L
View
36 36819024 E156G
S
S
COVID-19
G
L
View
37 36819024 157delF
S
S
COVID-19
G
L
View
38 36819024 158delR
S
S
COVID-19
G
L
View
39 36819024 Q173R
S
S
COVID-19
G
L
View
40 36819024 A222V
S
S
COVID-19
G
L
View
41 36819024 A262S
S
S
COVID-19
G
L
View
42 36819024 Q414K
S
S
COVID-19
G
L
View
43 36819024 G446V
S
S
COVID-19
G
L
View
44 36819024 L452R
S
S
COVID-19
G
L
View
45 36819024 R454K
S
S
COVID-19
G
L
View
46 36819024 T478K
S
S
COVID-19
G
L
View
47 36819024 E484Q
S
S
COVID-19
G
L
View
48 36819024 S494P
S
S
COVID-19
G
L
View
49 36819024 P499R
S
S
COVID-19
G
L
View
50 36819024 D614G
S
S
COVID-19
G
L
View
51 36819024 Q677H
S
S
COVID-19
G
L
View
52 36819024 P681R
S
S
COVID-19
G
L
View
53 36819024 R683W
S
S
COVID-19
G
L
View
54 36819024 D950N
S
S
COVID-19
G
L
View
55 36819024 S1242I
S
S
COVID-19
G
L
View
56 36819024 R158G
S
S
COVID-19
G
L
View
57 36819024 Q954Y
S
S
COVID-19
G
L
View
58 36819024 H1101D
S
S
COVID-19
L
View
59 36819024 S982A
S
S
COVID-19
L
View
60 36819024 V1104L
S
S
COVID-19
L
View
61 36819024 I285S
S
S
COVID-19
L
View
62 36819024 I199L
NSP6
ORF1a
COVID-19
L
View
63 36819024 I210V
NSP6
ORF1a
COVID-19
L
View
64 36819024 M211L
NSP6
ORF1a
COVID-19
L
View
65 36819024 L212S
NSP6
ORF1a
COVID-19
L
View
66 36819024 V213I
NSP6
ORF1a
COVID-19
L
View
67 36819024 214delY
NSP6
ORF1a
COVID-19
L
View
68 36819024 C215A
NSP6
ORF1a
COVID-19
L
View
69 36819024 F216L
NSP6
ORF1a
COVID-19
L
View
70 36819024 I124V
NSP6
ORF1a
COVID-19
L
View
71 36819024 V149F
NSP6
ORF1a
COVID-19
L
View
72 36819024 V1762F
NSP3
ORF1a
COVID-19
L
View
73 36819024 K412N
NSP3
ORF1a
COVID-19
L
View
74 36819024 Q168H
NSP14
ORF1b
COVID-19
L
View
75 36819024 M169V
NSP14
ORF1b
COVID-19
L
View
76 36819024 S171X
NSP14
ORF1b
COVID-19
L
View
77 36819024 D172H
NSP14
ORF1b
COVID-19
L
View
78 36819024 L174X
NSP14
ORF1b
COVID-19
L
View
79 36819024 N176S
NSP14
ORF1b
COVID-19
L
View
80 36819024 A394V
NSP14
ORF1b
COVID-19
L
View
81 36819024 A185V
NSP12
ORF1b
COVID-19
L
View
82 36819024 V381A
NSP12
ORF1b
COVID-19
L
View
83 36819024 P323L
NSP12
ORF1b
COVID-19
L
View
84 36819024 Q57H
NS3
ORF3a
COVID-19
L
View
85 36819024 G254X
NS3
ORF3a
COVID-19
L
View
86 36819024 R203K
N
N
COVID-19
L
View
87 36819024 G204R
N
N
COVID-19
L
View
88 36819024 D371V
N
N
COVID-19
L
View
89 36819024 L27F
E
E
COVID-19
L
View
90 36819024 L21F
E
E
COVID-19
L
View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.