All Curated Mutation Sites in SARS-CoV-2

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The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.

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Virus Gene/Protein

Disease

Description

For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

Furin cleavage site

Methyltransferase

Non-coding region

Keyword: COVID-19-36841805

ID	PMID	Mutation	Gene/Protein/Region	Encoding Gene/Protein	Disease	Description	Detail
1	36841805	D614G	S	S	COVID-19	R	View
2	36841805	G50N	ORF9c	ORF9c	COVID-19	R	View
3	36841805	T60A	ORF9b	ORF9b	COVID-19	R	View
4	36841805	S24L	ORF8	ORF8	COVID-19	R	View
5	36841805	T40I	ORF7b	ORF7b	COVID-19	R	View
6	36841805	T120I	ORF7a	ORF7a	COVID-19	R	View
7	36841805	D61L	ORF6	ORF6	COVID-19	R	View
8	36841805	S26L	ORF3a	ORF3a	COVID-19	R	View
9	36841805	D63G	N	N	COVID-19	R	View
10	36841805	T35I	NSP9	ORF1a	COVID-19	R	View
11	36841805	Q24R	NSP8	ORF1a	COVID-19	R	View
12	36841805	L71F	NSP7	ORF1a	COVID-19	R	View
13	36841805	T77A	NSP6	ORF1a	COVID-19	R	View
14	36841805	T492I	NSP4	ORF1a	COVID-19	R	View
15	36841805	P1228L	NSP3	ORF1a	COVID-19	R	View
16	36841805	T85I	NSP2	ORF1a	COVID-19	R	View
17	36841805	R216C	NSP16	ORF1b	COVID-19	R	View
18	36841805	T112I	NSP15	ORF1b	COVID-19	R	View
19	36841805	A394V	NSP14	ORF1b	COVID-19	R	View
20	36841805	P77L	NSP13	ORF1b	COVID-19	R	View
21	36841805	P323L	NSP12	ORF1b	COVID-19	R	View
22	36841805	S6L	NSP11	ORF1a	COVID-19	R	View
23	36841805	T102I	NSP10	ORF1a	COVID-19	R	View
24	36841805	S135R	NSP1	ORF1a	COVID-19	R	View
25	36841805	D377Y	N	N	COVID-19	R	View
26	36841805	R203M	N	N	COVID-19	R	View
27	36841805	G204R	N	N	COVID-19	R	View
28	36841805	G215C	N	N	COVID-19	R	View
29	36841805	S223F	N	N	COVID-19	R	View
30	36841805	A63T	M	M	COVID-19	R	View
31	36841805	I82T	M	M	COVID-19	R	View
32	36841805	Q19E	M	M	COVID-19	R	View
33	36841805	D3G	M	M	COVID-19	R	View
34	36841805	T9I	E	E	COVID-19	R	View

Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note

D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.

G
The study mentioned the virus genotype/subtype information.

R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.

S
The study provided sequence information or accession numbers.

L
The study provided the geographic region/country of data origin.

C
The study provided clinical baseline information.

I
The study involved information related to immune.

T
The study involved host target genes.