All Curated Mutation Sites in SARS-CoV-2 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: COVID-19-36925722
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 36925722 69_70del
S
S
COVID-19
G
R
S
View
2 36925722 L452R
S
S
COVID-19
G
R
S
View
3 36925722 F486V
S
S
COVID-19
G
R
S
View
4 36925722 T19I
S
S
COVID-19
G
R
S
View
5 36925722 G142D
S
S
COVID-19
G
R
S
View
6 36925722 V213G
S
S
COVID-19
G
R
S
View
7 36925722 S371F
S
S
COVID-19
G
R
S
View
8 36925722 S373P
S
S
COVID-19
G
R
S
View
9 36925722 S375F
S
S
COVID-19
G
R
S
View
10 36925722 T376A
S
S
COVID-19
G
R
S
View
11 36925722 D405N
S
S
COVID-19
G
R
S
View
12 36925722 R408S
S
S
COVID-19
G
R
S
View
13 36925722 K417N
S
S
COVID-19
G
R
S
View
14 36925722 N440K
S
S
COVID-19
G
R
S
View
15 36925722 S477N
S
S
COVID-19
G
R
S
View
16 36925722 T478K
S
S
COVID-19
G
R
S
View
17 36925722 E484A
S
S
COVID-19
G
R
S
View
18 36925722 Q498R
S
S
COVID-19
G
R
S
View
19 36925722 N501Y
S
S
COVID-19
G
R
S
View
20 36925722 Y505H
S
S
COVID-19
G
R
S
View
21 36925722 D614G
S
S
COVID-19
G
R
S
View
22 36925722 H655Y
S
S
COVID-19
G
R
S
View
23 36925722 N679K
S
S
COVID-19
G
R
S
View
24 36925722 P681H
S
S
COVID-19
G
R
S
View
25 36925722 N764K
S
S
COVID-19
G
R
S
View
26 36925722 D796Y
S
S
COVID-19
G
R
S
View
27 36925722 Q954H
S
S
COVID-19
G
R
S
View
28 36925722 N969K
S
S
COVID-19
G
R
S
View
29 36925722 L24S
S
S
COVID-19
G
R
S
View
30 36925722 25_27del
S
S
COVID-19
G
R
S
View
31 36925722 G339D
S
S
COVID-19
G
R
S
View
32 36925722 Q493R
S
S
COVID-19
G
R
S
View
33 36925722 K147E
S
S
COVID-19
G
R
S
View
34 36925722 W152R
S
S
COVID-19
G
R
S
View
35 36925722 F157L
S
S
COVID-19
G
R
S
View
36 36925722 I210V
S
S
COVID-19
G
R
S
View
37 36925722 G257S
S
S
COVID-19
G
R
S
View
38 36925722 G339H
S
S
COVID-19
G
R
S
View
39 36925722 G446S
S
S
COVID-19
G
R
S
View
40 36925722 N460K
S
S
COVID-19
G
R
S
View
41 36925722 L452Q
S
S
COVID-19
G
R
S
View
42 36925722 S704L
S
S
COVID-19
G
R
S
View
43 36925722 F486S
RBD
S
COVID-19
G
R
View
44 36925722 K356T
RBD
S
COVID-19
G
R
View
45 36925722 R346T
RBD
S
COVID-19
G
R
View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.