All Curated Mutation Sites in SARS-CoV-2 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: COVID-19-36992510
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 36992510 A1020T
S
S
COVID-19
G
R
S
C
L
View
2 36992510 A372S
S
S
COVID-19
G
R
S
C
L
View
3 36992510 A67T
S
S
COVID-19
G
R
S
C
L
View
4 36992510 D1163Y
S
S
COVID-19
G
R
S
C
L
View
5 36992510 D614G
S
S
COVID-19
G
R
S
C
L
View
6 36992510 D950N
S
S
COVID-19
G
R
S
C
L
View
7 36992510 E1202Q
S
S
COVID-19
G
R
S
C
L
View
8 36992510 E156G
S
S
COVID-19
G
R
S
C
L
View
9 36992510 E281Q
S
S
COVID-19
G
R
S
C
L
View
10 36992510 G1124C
S
S
COVID-19
G
R
S
C
L
View
11 36992510 G1219C
S
S
COVID-19
G
R
S
C
L
View
12 36992510 G1267R
S
S
COVID-19
G
R
S
C
L
View
13 36992510 G142D
S
S
COVID-19
G
R
S
C
L
View
14 36992510 I742N
S
S
COVID-19
G
R
S
C
L
View
15 36992510 I850L
S
S
COVID-19
G
R
S
C
L
View
16 36992510 L452R
S
S
COVID-19
G
R
S
C
L
View
17 36992510 M153I
S
S
COVID-19
G
R
S
C
L
View
18 36992510 N185D
S
S
COVID-19
G
R
S
C
L
View
19 36992510 P174S
S
S
COVID-19
G
R
S
C
L
View
20 36992510 P330L
S
S
COVID-19
G
R
S
C
L
View
21 36992510 P681R
S
S
COVID-19
G
R
S
C
L
View
22 36992510 T19R
S
S
COVID-19
G
R
S
C
L
View
23 36992510 T250I
S
S
COVID-19
G
R
S
C
L
View
24 36992510 T29A
S
S
COVID-19
G
R
S
C
L
View
25 36992510 T478K
S
S
COVID-19
G
R
S
C
L
View
26 36992510 T696S
S
S
COVID-19
G
R
S
C
L
View
27 36992510 T95I
S
S
COVID-19
G
R
S
C
L
View
28 36992510 V1228L
S
S
COVID-19
G
R
S
C
L
View
29 36992510 V382L
S
S
COVID-19
G
R
S
C
L
View
30 36992510 V915I
S
S
COVID-19
G
R
S
C
L
View
31 36992510 A119S
N
N
COVID-19
G
R
S
C
L
View
32 36992510 A359S
N
N
COVID-19
G
R
S
C
L
View
33 36992510 D377Y
N
N
COVID-19
G
R
S
C
L
View
34 36992510 D63G
N
N
COVID-19
G
R
S
C
L
View
35 36992510 E253D
N
N
COVID-19
G
R
S
C
L
View
36 36992510 G215C
N
N
COVID-19
G
R
S
C
L
View
37 36992510 L139S
N
N
COVID-19
G
R
S
C
L
View
38 36992510 P364L
N
N
COVID-19
G
R
S
C
L
View
39 36992510 R203M
N
N
COVID-19
G
R
S
C
L
View
40 36992510 R319H
N
N
COVID-19
G
R
S
C
L
View
41 36992510 R41Q
N
N
COVID-19
G
R
S
C
L
View
42 36992510 S232G
N
N
COVID-19
G
R
S
C
L
View
43 36992510 T24I
N
N
COVID-19
G
R
S
C
L
View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.