All Curated Mutation Sites in SARS-CoV-2 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: COVID-19-37059256
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 37059256 A222V
S
S
COVID-19
R
S
L
View
2 37059256 A831V
S
S
COVID-19
R
S
L
View
3 37059256 D614G
S
S
COVID-19
R
S
L
View
4 37059256 D80Y
S
S
COVID-19
R
S
L
View
5 37059256 E484K
S
S
COVID-19
R
S
L
View
6 37059256 F490S
S
S
COVID-19
R
S
L
View
7 37059256 L452R
S
S
COVID-19
R
S
L
View
8 37059256 N440K
S
S
COVID-19
R
S
L
View
9 37059256 N501Y
S
S
COVID-19
R
S
L
View
10 37059256 P681H
S
S
COVID-19
R
S
L
View
11 37059256 P681R
S
S
COVID-19
R
S
L
View
12 37059256 R346K
S
S
COVID-19
R
S
L
View
13 37059256 R346S
S
S
COVID-19
R
S
L
View
14 37059256 S98F
S
S
COVID-19
R
S
L
View
15 37059256 R436K
RBD
S
COVID-19
R
S
L
View
16 37059256 R436S
RBD
S
COVID-19
R
S
L
View
17 37059256 Q27X
ORF8
ORF8
COVID-19
R
S
L
View
18 37059256 P314L
ORF1b
ORF1b
COVID-19
R
S
L
View
19 37059256 T1001I
ORF1ab
ORF1ab
COVID-19
R
S
L
View
20 37059256 S235F
N
N
COVID-19
R
S
L
View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.