All Curated Mutation Sites in SARS-CoV-2

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The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.

Browse Data by Virus Gene/Protein/Region, Disease OR Description

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Virus Gene/Protein

Disease

Description

For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

Furin cleavage site

Methyltransferase

Non-coding region

Keyword: COVID-19-37060743

ID	PMID	Mutation	Gene/Protein/Region	Encoding Gene/Protein	Disease	Description	Detail
1	37060743	T21I	3CLpro	ORF1a	COVID-19	D G L	View
2	37060743	G15S	3CLpro	ORF1a	COVID-19	D G L	View
3	37060743	A173T	3CLpro	ORF1a	COVID-19	D	View
4	37060743	A173V	3CLpro	ORF1a	COVID-19	D	View
5	37060743	D248E	3CLpro	ORF1a	COVID-19	D	View
6	37060743	D48Y	3CLpro	ORF1a	COVID-19	D	View
7	37060743	E166A	3CLpro	ORF1a	COVID-19	D	View
8	37060743	E166G	3CLpro	ORF1a	COVID-19	D	View
9	37060743	E166V	3CLpro	ORF1a	COVID-19	D	View
10	37060743	F140A	3CLpro	ORF1a	COVID-19	D	View
11	37060743	F140L	3CLpro	ORF1a	COVID-19	D	View
12	37060743	H164N	3CLpro	ORF1a	COVID-19	D	View
13	37060743	H172F	3CLpro	ORF1a	COVID-19	D	View
14	37060743	H172Q	3CLpro	ORF1a	COVID-19	D	View
15	37060743	H172Y	3CLpro	ORF1a	COVID-19	D	View
16	37060743	L167F	3CLpro	ORF1a	COVID-19	D	View
17	37060743	L50F	3CLpro	ORF1a	COVID-19	D	View
18	37060743	M165T	3CLpro	ORF1a	COVID-19	D	View
19	37060743	M49I	3CLpro	ORF1a	COVID-19	D	View
20	37060743	M49L	3CLpro	ORF1a	COVID-19	D	View
21	37060743	P252L	3CLpro	ORF1a	COVID-19	D	View
22	37060743	Q189K	3CLpro	ORF1a	COVID-19	D	View
23	37060743	Q192L	3CLpro	ORF1a	COVID-19	D	View
24	37060743	Q192P	3CLpro	ORF1a	COVID-19	D	View
25	37060743	Q192S	3CLpro	ORF1a	COVID-19	D	View
26	37060743	Q192T	3CLpro	ORF1a	COVID-19	D	View
27	37060743	S144A	3CLpro	ORF1a	COVID-19	D	View
28	37060743	S144E	3CLpro	ORF1a	COVID-19	D	View
29	37060743	S144F	3CLpro	ORF1a	COVID-19	D	View
30	37060743	S144G	3CLpro	ORF1a	COVID-19	D	View
31	37060743	S144T	3CLpro	ORF1a	COVID-19	D	View
32	37060743	T135I	3CLpro	ORF1a	COVID-19	D	View
33	37060743	T304I	3CLpro	ORF1a	COVID-19	D	View
34	37060743	T45I	3CLpro	ORF1a	COVID-19	D	View
35	37060743	V186G	3CLpro	ORF1a	COVID-19	D	View
36	37060743	Y54A	3CLpro	ORF1a	COVID-19	D	View
37	37060743	Y54C	3CLpro	ORF1a	COVID-19	D	View

Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note

D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.

G
The study mentioned the virus genotype/subtype information.

R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.

S
The study provided sequence information or accession numbers.

L
The study provided the geographic region/country of data origin.

C
The study provided clinical baseline information.

I
The study involved information related to immune.

T
The study involved host target genes.