All Curated Mutation Sites in SARS-CoV-2 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: COVID-19-37107785
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 37107785 D614G
S
S
COVID-19
G
R
S
L
View
2 37107785 D681R
S
S
COVID-19
G
R
S
L
View
3 37107785 D950N
S
S
COVID-19
G
R
S
L
View
4 37107785 E484K
S
S
COVID-19
G
R
S
L
View
5 37107785 E484N
S
S
COVID-19
G
R
S
L
View
6 37107785 G142D
S
S
COVID-19
G
R
S
L
View
7 37107785 G339D
S
S
COVID-19
G
R
S
L
View
8 37107785 H655Y
S
S
COVID-19
G
R
S
L
View
9 37107785 L452R
S
S
COVID-19
G
R
S
L
View
10 37107785 N501Y
S
S
COVID-19
G
R
S
L
View
11 37107785 P681H
S
S
COVID-19
G
R
S
L
View
12 37107785 P681R
S
S
COVID-19
G
R
S
L
View
13 37107785 Q493R
S
S
COVID-19
G
R
S
L
View
14 37107785 R346K
S
S
COVID-19
G
R
S
L
View
15 37107785 T19R
S
S
COVID-19
G
R
S
L
View
16 37107785 T274T
S
S
COVID-19
G
R
S
L
View
17 37107785 T474K
S
S
COVID-19
G
R
S
L
View
18 37107785 T478K
S
S
COVID-19
G
R
S
L
View
19 37107785 T95I
S
S
COVID-19
G
R
S
L
View
20 37107785 Y145N
S
S
COVID-19
G
R
S
L
View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.