All Curated Mutation Sites in SARS-CoV-2 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: COVID-19-37153142
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 37153142 D405N
S
S
COVID-19
G
R
S
I
View
2 37153142 T95I
S
S
COVID-19
G
R
S
I
View
3 37153142 V213G
S
S
COVID-19
G
R
S
I
View
4 37153142 T478K
S
S
COVID-19
G
R
S
T
View
5 37153142 A222V
S
S
COVID-19
G
R
S
I
View
6 37153142 P681R
S
S
COVID-19
G
R
S
I
View
7 37153142 H655Y
S
S
COVID-19
G
R
S
View
8 37153142 P26S
S
S
COVID-19
G
R
S
I
View
9 37153142 R190S
S
S
COVID-19
G
R
S
View
10 37153142 E484K
S
S
COVID-19
G
R
S
I
View
11 37153142 L18F
S
S
COVID-19
G
R
S
I
View
12 37153142 G446S
S
S
COVID-19
G
R
S
I
View
13 37153142 A701V
S
S
COVID-19
G
R
S
I
View
14 37153142 P681H
S
S
COVID-19
G
R
S
I
View
15 37153142 N501Y
S
S
COVID-19
G
R
S
View
16 37153142 D614G
S
S
COVID-19
G
R
S
View
17 37153142 A570D
S
S
COVID-19
G
R
S
View
18 37153142 N764K
S
S
COVID-19
G
R
S
View
19 37153142 Q498R
S
S
COVID-19
G
R
S
I
View
20 37153142 D253G
S
S
COVID-19
R
S
View
21 37153142 D80Y
S
S
COVID-19
R
S
I
View
22 37153142 K1191N
S
S
COVID-19
R
S
View
23 37153142 L5F
S
S
COVID-19
R
S
View
24 37153142 Q173H
S
S
COVID-19
R
S
I
View
25 37153142 S13I
S
S
COVID-19
R
S
View
26 37153142 S98F
S
S
COVID-19
R
S
I
View
27 37153142 T572I
S
S
COVID-19
R
S
I
View
28 37153142 W152C
S
S
COVID-19
R
S
I
View
29 37153142 Y144V
S
S
COVID-19
R
S
View
30 37153142 R408S
S
S
COVID-19
G
R
S
View
31 37153142 S371F
S
S
COVID-19
G
R
S
I
View
32 37153142 S477N
S
S
COVID-19
G
R
S
View
33 37153142 S704L
S
S
COVID-19
G
R
S
I
View
34 37153142 T376A
S
S
COVID-19
G
R
S
I
View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.