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Virus Gene/Protein ORF1a ORF1b ORF3a S E M N ORF7a ORF7b ORF8 ORF1ab ORF9b ORF10 ORF6 ORF9c

Disease COVID-19All Cell line Cystic Fibrosis Pediatric Multisystem Inflammatory Disease, COVID-19 related Thrombosis, COVID-19 related HIV Infections

Description Genotype/Subtype Immune Target gene Clinical data Treatment Location Sequence data

For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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ORF1a

  

ORF1b

  

ORF3a

  

3CLpro

  

3'UTR

  

5'UTR

  

RBD

  

ORF7b-ORF8

  

upstream of N

  

Furin cleavage site

  

E

  

endoRNase

  

Exonuclease

  

S

  

NSP13

  

NSP3

  

M

  

Mpro

  

Methyltransferase

  

N

  

NSP14

  

NSP12

  

Non-coding region

  

NP

  

NS3

  

NS7a

  

NS7b

  

NS8

  

NSP5

  

NSP1

  

NSP10

  

NSP11

  

NSP15

  

NSP16

  

NSP2

  

NSP4

  

NSP6

  

NSP7

  

NSP8

  

NSP9

  

NTD

  

ORF8

  

ORF1ab

  

ORF9b

  

ORF10

  

ORF3

  

ORF6

  

ORF7a

  

ORF7b

  

ORF9

  

ORF9c

  

PLpro

  

RdRp

  

RBM

  

Replicase

  

RNA primase

  

• Mutation
• Sequence

ID	PMID	Mutation	Gene/Protein/Region	Encoding Gene/Protein	Disease	Description	Detail
1	37224159	T19I	S;NSP9	S;ORF1a	COVID-19	G R L	View
2	37224159	G21641T	S	S	COVID-19	G R L	View
3	37224159	G21987A	S	S	COVID-19	G R L	View
4	37224159	A22001G	S	S	COVID-19	G R L	View
5	37224159	T22016C	S	S	COVID-19	G R L	View
6	37224159	C22033A	S	S	COVID-19	G R L	View
7	37224159	A22190G	S	S	COVID-19	G R L	View
8	37224159	T22200G	S	S	COVID-19	G R L	View
9	37224159	G22331A	S	S	COVID-19	G R L	View
10	37224159	GG22577CA	S	S	COVID-19	G R L	View
11	37224159	C22674T	S	S	COVID-19	G R L	View
12	37224159	T22679C	S	S	COVID-19	G R L	View
13	37224159	C22686T	S	S	COVID-19	G R L	View
14	37224159	A22688G	S	S	COVID-19	G R L	View
15	37224159	A22720G	S	S	COVID-19	G R L	View
16	37224159	G22775A	S	S	COVID-19	G R L	View
17	37224159	A22786C	S	S	COVID-19	G R L	View
18	37224159	G22813T	S	S	COVID-19	G R L	View
19	37224159	T22882G	S	S	COVID-19	G R L	View
20	37224159	G22898A	S	S	COVID-19	G R L	View
21	37224159	T22942G	S	S	COVID-19	G R L	View
22	37224159	G22992A	S	S	COVID-19	G R L	View
23	37224159	C22995A	S	S	COVID-19	G R L	View
24	37224159	A23013C	S	S	COVID-19	G R L	View
25	37224159	A23055G	S	S	COVID-19	G R L	View
26	37224159	A23063T	S	S	COVID-19	G R L	View
27	37224159	A23283T	S	S	COVID-19	G R L	View
28	37224159	A23403G	S	S	COVID-19	G R L	View
29	37224159	C23525T	S	S	COVID-19	G R L	View
30	37224159	T23599G	S	S	COVID-19	G R L	View
31	37224159	C23604A	S	S	COVID-19	G R L	View
32	37224159	C23854A	S	S	COVID-19	G R L	View
33	37224159	G23948T	S	S	COVID-19	G R L	View
34	37224159	A24424T	S	S	COVID-19	G R L	View
35	37224159	T24469A	S	S	COVID-19	G R L	View
36	37224159	C25000T	S	S	COVID-19	G R L	View
37	37224159	GGG28881AAC	S	S	COVID-19	G R L	View
38	37224159	A27S	S	S	COVID-19	G R L	View
39	37224159	D1146D	S	S	COVID-19	G R L	View
40	37224159	D405N	S	S	COVID-19	G R L	View
41	37224159	D574V	S	S	COVID-19	G R L	View
42	37224159	D614G	S	S	COVID-19	G R L	View
43	37224159	D796Y	S	S	COVID-19	G R L	View
44	37224159	E484A	S	S	COVID-19	G R L	View
45	37224159	F157L	S	S	COVID-19	G R L	View
46	37224159	G142D	S	S	COVID-19	G R L	View
47	37224159	G257S	S	S	COVID-19	G R L	View
48	37224159	G339H	S	S	COVID-19	G R L	View
49	37224159	G446S	S	S	COVID-19	G R L	View
50	37224159	H655Y	S	S	COVID-19	G R L	View
51	37224159	I210V	S	S	COVID-19	G R L	View
52	37224159	K147E	S	S	COVID-19	G R L	View
53	37224159	K386K	S	S	COVID-19	G R L	View
54	37224159	K417N	S	S	COVID-19	G R L	View
55	37224159	24delL	S	S	COVID-19	G R L	View
56	37224159	L24S	S	S	COVID-19	G R L	View
57	37224159	N440K	S	S	COVID-19	G R L	View
58	37224159	N460K	S	S	COVID-19	G R L	View
59	37224159	N501Y	S	S	COVID-19	G R L	View
60	37224159	N679K	S	S	COVID-19	G R L	View
61	37224159	N764K	S	S	COVID-19	G R L	View
62	37224159	N969K	S	S	COVID-19	G R L	View
63	37224159	P681H	S	S	COVID-19	G R L	View
64	37224159	Q498R	S	S	COVID-19	G R L	View
65	37224159	Q954H	S	S	COVID-19	G R L	View
66	37224159	R408S	S	S	COVID-19	G R L	View
67	37224159	S371F	S	S	COVID-19	G R L	View
68	37224159	S373P	S	S	COVID-19	G R L	View
69	37224159	S375F	S	S	COVID-19	G R L	View
70	37224159	S477N	S	S	COVID-19	G R L	View
71	37224159	T376A	S	S	COVID-19	G R L	View
72	37224159	T478K	S	S	COVID-19	G R L	View
73	37224159	V213G	S	S	COVID-19	G R L	View
74	37224159	W152R	S	S	COVID-19	G R L	View
75	37224159	Y505H	S	S	COVID-19	G R L	View
76	37224159	C27807T	ORF7b	ORF7b	COVID-19	G R L	View
77	37224159	L17L	ORF7b	ORF7b	COVID-19	G R L	View
78	37224159	C27527T	ORF7a	ORF7a	COVID-19	G R L	View
79	37224159	P45L	ORF7a	ORF7a	COVID-19	G R L	View
80	37224159	A27259C	ORF6	ORF6	COVID-19	G R L	View
81	37224159	GAT27382CTC	ORF6	ORF6	COVID-19	G R L	View
82	37224159	D61L	ORF6	ORF6	COVID-19	G R L	View
83	37224159	M19M	ORF6	ORF6	COVID-19	G R L	View
84	37224159	T64T	ORF3a;NSP3	ORF3a;ORF1a	COVID-19	G R L	View
85	37224159	C25416T	ORF3a	ORF3a	COVID-19	G R L	View
86	37224159	C26060T	ORF3a	ORF3a	COVID-19	G R L	View
87	37224159	T2231I	ORF3a	ORF3a	COVID-19	G R L	View
88	37224159	T223I	ORF3a	ORF3a	COVID-19	G R L	View
89	37224159	E210V	NTD	S	COVID-19	G R L	View
90	37224159	C12741T	NSP9	ORF1a	COVID-19	G R L	View
91	37224159	C12880T	NSP9	ORF1a	COVID-19	G R L	View
92	37224159	I65I	NSP9	ORF1a	COVID-19	G R L	View
93	37224159	A12140G	NSP8	ORF1a	COVID-19	G R L	View
94	37224159	A12444G	NSP8	ORF1a	COVID-19	G R L	View
95	37224159	N118S	NSP8	ORF1a	COVID-19	G R L	View
96	37224159	T17A	NSP8	ORF1a	COVID-19	G R L	View
97	37224159	C11224T	NSP6	ORF1a	COVID-19	G R L	View
98	37224159	T11288A	NSP6	ORF1a	COVID-19	G R L	View
99	37224159	G11291A	NSP6	ORF1a	COVID-19	G R L	View
100	37224159	T11296G	NSP6	ORF1a	COVID-19	G R L	View
101	37224159	F108L	NSP6	ORF1a	COVID-19	G R L	View
102	37224159	G107S	NSP6	ORF1a	COVID-19	G R L	View
103	37224159	106delS	NSP6	ORF1a	COVID-19	G R L	View
104	37224159	S106T	NSP6	ORF1a	COVID-19	G R L	View
105	37224159	V84V	NSP6	ORF1a	COVID-19	G R L	View
106	37224159	C10198T	NSP5	ORF1a	COVID-19	G R L	View
107	37224159	G10447A	NSP5	ORF1a	COVID-19	G R L	View
108	37224159	C10449A	NSP5	ORF1a	COVID-19	G R L	View
109	37224159	D48D	NSP5	ORF1a	COVID-19	G R L	View
110	37224159	P132H	NSP5	ORF1a	COVID-19	G R L	View
111	37224159	R131R	NSP5	ORF1a	COVID-19	G R L	View
112	37224159	C10029T	NSP4	ORF1a	COVID-19	G R L	View
113	37224159	C8937T	NSP4	ORF1a	COVID-19	G R L	View
114	37224159	C9344T	NSP4	ORF1a	COVID-19	G R L	View
115	37224159	A9424G	NSP4	ORF1a	COVID-19	G R L	View
116	37224159	C9534T	NSP4	ORF1a	COVID-19	G R L	View
117	37224159	C9866T	NSP4	ORF1a	COVID-19	G R L	View
118	37224159	A128V	NSP4	ORF1a	COVID-19	G R L	View
119	37224159	L264F	NSP4	ORF1a	COVID-19	G R L	View
120	37224159	L438F	NSP4	ORF1a	COVID-19	G R L	View
121	37224159	T327I	NSP4	ORF1a	COVID-19	G R L	View
122	37224159	T492I	NSP4	ORF1a	COVID-19	G R L	View
123	37224159	V290V	NSP4	ORF1a	COVID-19	G R L	View
124	37224159	T2911C	NSP3;ORF3	ORF1a;ORF3a	COVID-19	G R L	View
125	37224159	T24I	NSP3;N	ORF1a;N	COVID-19	G R L	View
126	37224159	C28344T	NSP3	ORF1a	COVID-19	G R L	View
127	37224159	C3037T	NSP3	ORF1a	COVID-19	G R L	View
128	37224159	C3796T	NSP3	ORF1a	COVID-19	G R L	View
129	37224159	C3927T	NSP3	ORF1a	COVID-19	G R L	View
130	37224159	G4184A	NSP3	ORF1a	COVID-19	G R L	View
131	37224159	C4321T	NSP3	ORF1a	COVID-19	G R L	View
132	37224159	C4586T	NSP3	ORF1a	COVID-19	G R L	View
133	37224159	C5183T	NSP3	ORF1a	COVID-19	G R L	View
134	37224159	A534A	NSP3	ORF1a	COVID-19	G R L	View
135	37224159	D622D	NSP3	ORF1a	COVID-19	G R L	View
136	37224159	F106F	NSP3	ORF1a	COVID-19	G R L	View
137	37224159	G489S	NSP3	ORF1a	COVID-19	G R L	View
138	37224159	P822S	NSP3	ORF1a	COVID-19	G R L	View
139	37224159	S403L	NSP3	ORF1a	COVID-19	G R L	View
140	37224159	T183I	NSP3	ORF1a	COVID-19	G R L	View
141	37224159	T241I	NSP3	ORF1a	COVID-19	G R L	View
142	37224159	V359V	NSP3	ORF1a	COVID-19	G R L	View
143	37224159	C2710T	NSP2	ORF1a	COVID-19	G R L	View
144	37224159	L635L	NSP2	ORF1a	COVID-19	G R L	View
145	37224159	C19955T	NSP15	ORF1b	COVID-19	G R L	View
146	37224159	A20055G	NSP15	ORF1b	COVID-19	G R L	View
147	37224159	E145E	NSP15	ORF1b	COVID-19	G R L	View
148	37224159	T1121I	NSP15	ORF1b	COVID-19	G R L	View
149	37224159	T112I	NSP15	ORF1b	COVID-19	G R L	View
150	37224159	A18163G	NSP14	ORF1b	COVID-19	G R L	View
151	37224159	G18583A	NSP14	ORF1b	COVID-19	G R L	View
152	37224159	I42V	NSP14	ORF1b	COVID-19	G R L	View
153	37224159	V182I	NSP14	ORF1b	COVID-19	G R L	View
154	37224159	C16887T	NSP13	ORF1b	COVID-19	G R L	View
155	37224159	R392C	NSP13	ORF1b	COVID-19	G R L	View
156	37224159	Y217Y	NSP13	ORF1b	COVID-19	G R L	View
157	37224159	C14408T	NSP12	ORF1b	COVID-19	G R L	View
158	37224159	G15451A	NSP12	ORF1b	COVID-19	G R L	View
159	37224159	C15714T	NSP12	ORF1b	COVID-19	G R L	View
160	37224159	G662S	NSP12	ORF1b	COVID-19	G R L	View
161	37224159	L749L	NSP12	ORF1b	COVID-19	G R L	View
162	37224159	P314L	NSP12	ORF1b	COVID-19	G R L	View
163	37224159	S135R	NSP1	ORF1a	COVID-19	G R L	View
164	37224159	C28311T	N	N	COVID-19	G R L	View
165	37224159	A28363T	N	N	COVID-19	G R L	View
166	37224159	C28367T	N	N	COVID-19	G R L	View
167	37224159	A28370G	N	N	COVID-19	G R L	View
168	37224159	A29510C	N	N	COVID-19	G R L	View
169	37224159	31delE	N	N	COVID-19	G R L	View
170	37224159	G30G	N	N	COVID-19	G R L	View
171	37224159	P13L	N	N	COVID-19	G R L	View
172	37224159	R32C	N	N	COVID-19	G R L	View
173	37224159	S33G	N	N	COVID-19	G R L	View
174	37224159	S413R	N	N	COVID-19	G R L	View
175	37224159	C26577G	M	M	COVID-19	G R L	View
176	37224159	A26612T	M	M	COVID-19	G R L	View
177	37224159	G26709A	M	M	COVID-19	G R L	View
178	37224159	C26858T	M	M	COVID-19	G R L	View
179	37224159	A63T	M	M	COVID-19	G R L	View
180	37224159	F112F	M	M	COVID-19	G R L	View
181	37224159	Q19E	M	M	COVID-19	G R L	View
182	37224159	T30T	M	M	COVID-19	G R L	View
183	37224159	C26270T	E	E	COVID-19	G R L	View
184	37224159	A26275G	E	E	COVID-19	G R L	View
185	37224159	T11A	E	E	COVID-19	G R L	View
186	37224159	T9I	E	E	COVID-19	G R L	View