All Curated Mutation Sites in SARS-CoV-2

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The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.

Browse Data by Virus Gene/Protein/Region, Disease OR Description

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Virus Gene/Protein

Disease

Description

For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

Furin cleavage site

Methyltransferase

Non-coding region

Keyword: COVID-19-37270625

ID	PMID	Mutation	Gene/Protein/Region	Encoding Gene/Protein	Disease	Description	Detail
1	37270625	A484V	S	S	COVID-19	G R S C L	View
2	37270625	A688V	S	S	COVID-19	G R S C L	View
3	37270625	E484V	S	S	COVID-19	G R S C L	View
4	37270625	E96D	S	S	COVID-19	G R S C L	View
5	37270625	F981L	S	S	COVID-19	G R S C L	View
6	37270625	H681R	S	S	COVID-19	G R S C L	View
7	37270625	L167T	S	S	COVID-19	G R S C L	View
8	37270625	L455W	S	S	COVID-19	G R S C L	View
9	37270625	R346T	S	S	COVID-19	G R S C L	View
10	37270625	S477D	S	S	COVID-19	G R S C L	View
11	37270625	D936Y	S	S	COVID-19	G R S C L	View
12	37270625	E1195G	S	S	COVID-19	G R S C L	View
13	37270625	L981F	S	S	COVID-19	G R S C L	View
14	37270625	N978D	S	S	COVID-19	G R S C L	View
15	37270625	S982L	S	S	COVID-19	G R S C L	View
16	37270625	V963F	S	S	COVID-19	G R S C L	View
17	37270625	F456L	RBD	S	COVID-19	G R S C L	View
18	37270625	K356T	RBD	S	COVID-19	G R S C L	View
19	37270625	K458M	RBD	S	COVID-19	G R S C L	View
20	37270625	M458K	RBD	S	COVID-19	G R S C L	View
21	37270625	N448S	RBD	S	COVID-19	G R S C L	View
22	37270625	P384L	RBD	S	COVID-19	G R S C L	View
23	37270625	S371F	RBD	S	COVID-19	G R S C L	View
24	37270625	V445A	RBD	S	COVID-19	G R S C L	View
25	37270625	S254F	NTD	S	COVID-19	G R S C L	View
26	37270625	N679K	Furin cleavage site	S	COVID-19	G R S C L	View
27	37270625	P681Y	Furin cleavage site	S	COVID-19	G R S C L	View
28	37270625	K548M	S	S	COVID-19	G R S C L	View
29	37270625	P681R	S	S	COVID-19	G R S C L	View
30	37270625	T24I	ORF7a	ORF7a	COVID-19	G R S C L	View
31	37270625	T39I	ORF7a	ORF7a	COVID-19	G R S C L	View
32	37270625	T6001C	ORF1a	ORF1a	COVID-19	G R S C L	View
33	37270625	A67V	S	S	COVID-19	G R S C L	View
34	37270625	D614G	S	S	COVID-19	G R S C L	View
35	37270625	D796Y	S	S	COVID-19	G R S C L	View
36	37270625	G339D	S	S	COVID-19	G R S C L	View
37	37270625	G446S	S	S	COVID-19	G R S C L	View
38	37270625	G496S	S	S	COVID-19	G R S C L	View
39	37270625	H655Y	S	S	COVID-19	G R S C L	View
40	37270625	K417N	S	S	COVID-19	G R S C L	View
41	37270625	L212I	S	S	COVID-19	G R S C L	View
42	37270625	N440K	S	S	COVID-19	G R S C L	View
43	37270625	N501Y	S	S	COVID-19	G R S C L	View
44	37270625	N764K	S	S	COVID-19	G R S C L	View
45	37270625	N856K	S	S	COVID-19	G R S C L	View
46	37270625	N969K	S	S	COVID-19	G R S C L	View
47	37270625	P681H	S	S	COVID-19	G R S C L	View
48	37270625	Q493R	S	S	COVID-19	G R S C L	View
49	37270625	Q498R	S	S	COVID-19	G R S C L	View
50	37270625	Q954H	S	S	COVID-19	G R S C L	View
51	37270625	S371L	S	S	COVID-19	G R S C L	View
52	37270625	S373P	S	S	COVID-19	G R S C L	View
53	37270625	S375F	S	S	COVID-19	G R S C L	View
54	37270625	S477N	S	S	COVID-19	G R S C L	View
55	37270625	T478K	S	S	COVID-19	G R S C L	View
56	37270625	T547K	S	S	COVID-19	G R S C L	View
57	37270625	T95I	S	S	COVID-19	G R S C L	View
58	37270625	Y145D	S	S	COVID-19	G R S C L	View
59	37270625	Y505H	S	S	COVID-19	G R S C L	View

Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note

D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.

G
The study mentioned the virus genotype/subtype information.

R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.

S
The study provided sequence information or accession numbers.

L
The study provided the geographic region/country of data origin.

C
The study provided clinical baseline information.

I
The study involved information related to immune.

T
The study involved host target genes.