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Virus Gene/Protein ORF1a ORF1b ORF3a S E M N ORF7a ORF7b ORF8 ORF1ab ORF9b ORF10 ORF6 ORF9c

Disease COVID-19All Cell line Cystic Fibrosis Pediatric Multisystem Inflammatory Disease, COVID-19 related Thrombosis, COVID-19 related HIV Infections

Description Genotype/Subtype Immune Target gene Clinical data Treatment Location Sequence data

For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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ORF1a

  

ORF1b

  

ORF3a

  

3CLpro

  

3'UTR

  

5'UTR

  

RBD

  

ORF7b-ORF8

  

upstream of N

  

Furin cleavage site

  

E

  

endoRNase

  

Exonuclease

  

S

  

NSP13

  

NSP3

  

M

  

Mpro

  

Methyltransferase

  

N

  

NSP14

  

NSP12

  

Non-coding region

  

NP

  

NS3

  

NS7a

  

NS7b

  

NS8

  

NSP5

  

NSP1

  

NSP10

  

NSP11

  

NSP15

  

NSP16

  

NSP2

  

NSP4

  

NSP6

  

NSP7

  

NSP8

  

NSP9

  

NTD

  

ORF8

  

ORF1ab

  

ORF9b

  

ORF10

  

ORF3

  

ORF6

  

ORF7a

  

ORF7b

  

ORF9

  

ORF9c

  

PLpro

  

RdRp

  

RBM

  

Replicase

  

RNA primase

  

• Mutation
• Sequence

ID	PMID	Mutation	Gene/Protein/Region	Encoding Gene/Protein	Disease	Description	Detail
1	37275159	A1501T	S	S	COVID-19	G R S C L	View
2	37275159	A2862T	S	S	COVID-19	G R S C L	View
3	37275159	A8530G	S	S	COVID-19	G R S C L	View
4	37275159	C2042A	S	S	COVID-19	G R S C L	View
5	37275159	C3438T	S	S	COVID-19	G R S C L	View
6	37275159	C56T	S	S	COVID-19	G R S C L	View
7	37275159	D1146D	S	S	COVID-19	G R S C L	View
8	37275159	F486V	S	S	COVID-19	G R S C L	View
9	37275159	G1016A	S	S	COVID-19	G R S C L	View
10	37275159	G10721A	S	S	COVID-19	G R S C L	View
11	37275159	G339D	S	S	COVID-19	G R S C L	View
12	37275159	G865A	S	S	COVID-19	G R S C L	View
13	37275159	N501Y	S	S	COVID-19	G R S C L	View
14	37275159	P681H	S	S	COVID-19	G R S C L	View
15	37275159	Q954H	S	S	COVID-19	G R S C L	View
16	37275159	S373P	S	S	COVID-19	G R S C L	View
17	37275159	S375F	S	S	COVID-19	G R S C L	View
18	37275159	T1117C	S	S	COVID-19	G R S C L	View
19	37275159	T1456G	S	S	COVID-19	G R S C L	View
20	37275159	T19I	S	S	COVID-19	G R S C L	View
21	37275159	T3190A	S	S	COVID-19	G R S C L	View
22	37275159	T376A	S	S	COVID-19	G R S C L	View
23	37275159	T638G	S	S	COVID-19	G R S C L	View
24	37275159	V213G	S	S	COVID-19	G R S C L	View
25	37275159	V289I	S	S	COVID-19	G R S C L	View
26	37275159	Y505H	S	S	COVID-19	G R S C L	View
27	37275159	L18L	ORF7b	ORF7b	COVID-19	G R S C L	View
28	37275159	C15C	ORF7a	ORF7a	COVID-19	G R S C L	View
29	37275159	T45C	ORF7a	ORF7a	COVID-19	G R S C L	View
30	37275159	C222T	ORF3a	ORF3a	COVID-19	G R S C L	View
31	37275159	S74S	ORF3a	ORF3a	COVID-19	G R S C L	View
32	37275159	T223I	ORF3a	ORF3a	COVID-19	G R S C L	View
33	37275159	T64T	ORF3a	ORF3a	COVID-19	G R S C L	View
34	37275159	R3574K	ORF1ab	ORF1ab	COVID-19	G R S C L	View
35	37275159	S2844G	ORF1ab	ORF1ab	COVID-19	G R S C L	View
36	37275159	Y1064N	ORF1ab	ORF1ab	COVID-19	G R S C L	View
37	37275159	L37F	ORF10	ORF10	COVID-19	G R S C L	View
38	37275159	P13L	N	N	COVID-19	G R S C L	View
39	37275159	S413R	N	N	COVID-19	G R S C L	View
40	37275159	D3N	M	M	COVID-19	G R S C L	View
41	37275159	Q19E	M	M	COVID-19	G R S C L	View
42	37275159	T9I	E	E	COVID-19	G R S C L	View
43	37275159	A28271T	upstream of N		COVID-19	G R S C L	View
44	37275159	C27889T	ORF7b-ORF8		COVID-19	G R S C L	View
45	37275159	C241T	5'UTR		COVID-19	G R S C L	View
46	37275159	G142D	S	S	COVID-19	G R S C L	View