All Curated Mutation Sites in SARS-CoV-2 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: COVID-19-37301830
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 37301830 A22V
S
S
COVID-19
G
R
S
C
L
 View
2 37301830 D950N
S
S
COVID-19
G
R
S
C
L
 View
3 37301830 E156G
S
S
COVID-19
G
R
S
C
L
 View
4 37301830 157delF
S
S
COVID-19
G
R
S
C
L
 View
5 37301830 P681R
S
S
COVID-19
G
R
S
C
L
 View
6 37301830 158delR
S
S
COVID-19
G
R
S
C
L
 View
7 37301830 S698L
S
S
COVID-19
G
R
S
C
L
 View
8 37301830 T19R
S
S
COVID-19
G
R
S
C
L
 View
9 37301830 D614G
S
S
COVID-19
G
R
S
C
L
 View
10 37301830 E484K
S
S
COVID-19
G
R
S
C
L
 View
11 37301830 L452R
S
S
COVID-19
G
R
S
C
L
 View
12 37301830 L981F
S
S
COVID-19
G
R
S
C
L
 View
13 37301830 G142D
NTD
S
COVID-19
G
R
S
I
C
L
 View
14 37301830 A701V
S
S
COVID-19
G
R
S
C
L
 View
15 37301830 D1118H
S
S
COVID-19
G
R
S
C
L
 View
16 37301830 D215G
S
S
COVID-19
G
R
S
C
L
 View
17 37301830 K417N
S
S
COVID-19
G
R
S
C
L
 View
18 37301830 L18F
S
S
COVID-19
G
R
S
C
L
 View
19 37301830 244delL
S
S
COVID-19
G
R
S
C
L
 View
20 37301830 L54F
S
S
COVID-19
G
R
S
C
L
 View
21 37301830 N501Y
S
S
COVID-19
G
R
S
C
L
 View
22 37301830 P681H
S
S
COVID-19
G
R
S
C
L
 View
23 37301830 S982A
S
S
COVID-19
G
R
S
C
L
 View
24 37301830 T716I
S
S
COVID-19
G
R
S
C
L
 View
25 37301830 D796Y
S
S
COVID-19
G
R
S
C
L
 View
26 37301830 N696K
S
S
COVID-19
G
R
S
C
L
 View
27 37301830 N764K
S
S
COVID-19
G
R
S
C
L
 View
28 37301830 N856K
S
S
COVID-19
G
R
S
C
L
 View
29 37301830 N969K
S
S
COVID-19
G
R
S
C
L
 View
30 37301830 T547K
S
S
COVID-19
G
R
S
C
L
 View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.