All Curated Mutation Sites in SARS-CoV-2 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: COVID-19-37342350
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 37342350 E484Q
RBD
S
COVID-19
G
R
S
C
L
View
2 37342350 144delY
S
S
COVID-19
G
R
S
I
C
L
View
3 37342350 D1118H
S
S
COVID-19
G
R
S
C
L
View
4 37342350 P681H
S
S
COVID-19
G
R
S
I
C
L
View
5 37342350 H245Y
S
S
COVID-19
G
R
S
C
L
View
6 37342350 P26S
S
S
COVID-19
G
R
S
C
L
View
7 37342350 S477N
S
S
COVID-19
G
R
S
I
C
L
View
8 37342350 T1027I
S
S
COVID-19
G
R
S
C
L
View
9 37342350 V126A
S
S
COVID-19
G
R
S
C
L
View
10 37342350 W152R
S
S
COVID-19
G
R
S
C
L
View
11 37342350 E484K
S
S
COVID-19
G
R
S
I
C
L
View
12 37342350 N501Y
S
S
COVID-19
G
R
S
I
C
L
View
13 37342350 K417N
S
S
COVID-19
G
R
S
I
C
L
View
14 37342350 A701V
S
S
COVID-19
G
R
S
C
L
View
15 37342350 D215G
S
S
COVID-19
G
R
S
C
L
View
16 37342350 D80A
S
S
COVID-19
G
R
S
C
L
View
17 37342350 N439K
S
S
COVID-19
G
R
S
I
C
L
View
18 37342350 L189F
S
S
COVID-19
G
R
S
C
L
View
19 37342350 V772I
S
S
COVID-19
G
R
S
C
L
View
20 37342350 A570D
S
S
COVID-19
G
R
S
C
L
View
21 37342350 S982A
S
S
COVID-19
G
R
S
C
L
View
22 37342350 T716I
S
S
COVID-19
G
R
S
C
L
View
23 37342350 D614G
S
S
COVID-19
G
R
S
I
C
L
View
24 37342350 P681R
S
S
COVID-19
G
R
S
I
C
L
View
25 37342350 D950N
S
S
COVID-19
G
R
S
C
L
View
26 37342350 L452R
S
S
COVID-19
G
R
S
I
C
L
View
27 37342350 T19R
S
S
COVID-19
G
R
S
C
L
View
28 37342350 T478K
S
S
COVID-19
G
R
S
I
C
L
View
29 37342350 E156G
S
S
COVID-19
G
R
S
C
L
View
30 37342350 G142D
S
S
COVID-19
G
R
S
C
L
View
31 37342350 A222V
S
S
COVID-19
G
R
S
C
L
View
32 37342350 V70F
S
S
COVID-19
G
R
S
C
L
View
33 37342350 T95I
S
S
COVID-19
G
R
S
C
L
View
34 37342350 W258L
S
S
COVID-19
G
R
S
C
L
View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.