All Curated Mutation Sites in SARS-CoV-2

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The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.

Browse Data by Virus Gene/Protein/Region, Disease OR Description

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Virus Gene/Protein

Disease

Description

For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

Furin cleavage site

Methyltransferase

Non-coding region

Keyword: COVID-19-37376693

ID	PMID	Mutation	Gene/Protein/Region	Encoding Gene/Protein	Disease	Description	Detail
1	37376693	A18163G	ORF1b	ORF1b	COVID-19	G R S L	View
2	37376693	C16616A	ORF1b	ORF1b	COVID-19	G R S L	View
3	37376693	I1566V	ORF1b	ORF1b	COVID-19	G R S L	View
4	37376693	T1050N	ORF1b	ORF1b	COVID-19	G R S L	View
5	37376693	C26270T	E	E	COVID-19	G R S L	View
6	37376693	T9I	E	E	COVID-19	G R S L	View
7	37376693	A22786C	S	S	COVID-19	G R S L	View
8	37376693	R408S	S	S	COVID-19	G R S L	View
9	37376693	T24163C	S	S	COVID-19	G R S L	View
10	37376693	A2139T	ORF1a	ORF1a	COVID-19	G R S L	View
11	37376693	G6680A	ORF1a	ORF1a	COVID-19	G R S L	View
12	37376693	H78Y	ORF3a	ORF3a	COVID-19	G R S L	View
13	37376693	V1393A	ORF1ab	ORF1ab	COVID-19	G R S L	View
14	37376693	A21222G	ORF1ab	ORF1ab	COVID-19	G R S L	View
15	37376693	C832T	ORF1ab	ORF1ab	COVID-19	G R S L	View
16	37376693	T7282C	ORF1ab	ORF1ab	COVID-19	G R S L	View
17	37376693	C241T	5'UTR		COVID-19	G R S L	View
18	37376693	C25672T	ORF3a	ORF3a	COVID-19	G R S L	View
19	37376693	L94F	ORF3a	ORF3a	COVID-19	G R S L	View
20	37376693	T2048I	ORF1b	ORF1b	COVID-19	G R S L	View
21	37376693	C10198T	ORF1ab	ORF1ab	COVID-19	G R S L	View
22	37376693	C17745T	ORF1ab	ORF1ab	COVID-19	G R S L	View
23	37376693	C19610T	ORF1ab	ORF1ab	COVID-19	G R S L	View
24	37376693	A156S	N	N	COVID-19	G R S L	View
25	37376693	G28739T	N	N	COVID-19	G R S L	View
26	37376693	C25961T	ORF3a	ORF3a	COVID-19	G R S L	View
27	37376693	T190I	ORF3a	ORF3a	COVID-19	G R S L	View
28	37376693	T7813C	ORF1ab	ORF1ab	COVID-19	G R S L	View
29	37376693	C23854A	S	S	COVID-19	G R S L	View
30	37376693	C25416T	S	S	COVID-19	G R S L	View
31	37376693	N440K	S	S	COVID-19	G R S L	View
32	37376693	N764K	S	S	COVID-19	G R S L	View
33	37376693	T22882G	S	S	COVID-19	G R S L	View
34	37376693	C7471T	ORF1ab	ORF1ab	COVID-19	G R S L	View
35	37376693	C20719T	ORF7a	ORF7a	COVID-19	G R S L	View
36	37376693	C27494T	ORF7a	ORF7a	COVID-19	G R S L	View
37	37376693	P34L	ORF7a	ORF7a	COVID-19	G R S L	View
38	37376693	C15738T	ORF1b	ORF1b	COVID-19	G R S L	View
39	37376693	C17285T	ORF1b	ORF1b	COVID-19	G R S L	View
40	37376693	S1273L	ORF1b	ORF1b	COVID-19	G R S L	View
41	37376693	G5515T	ORF1ab	ORF1ab	COVID-19	G R S L	View
42	37376693	A3301T	ORF1a	ORF1a	COVID-19	G R S L	View
43	37376693	E973K	ORF1a	ORF1a	COVID-19	G R S L	View
44	37376693	G11417T	ORF1a	ORF1a	COVID-19	G R S L	View
45	37376693	G3182A	ORF1a	ORF1a	COVID-19	G R S L	View
46	37376693	L1012F	ORF1a	ORF1a	COVID-19	G R S L	View
47	37376693	V3718F	ORF1a	ORF1a	COVID-19	G R S L	View
48	37376693	C10605T	ORF1ab	ORF1ab	COVID-19	G R S L	View
49	37376693	C12084T	ORF1ab	ORF1ab	COVID-19	G R S L	View
50	37376693	C4113T	ORF1ab	ORF1ab	COVID-19	G R S L	View
51	37376693	C5672T	ORF1ab	ORF1ab	COVID-19	G R S L	View
52	37376693	G15850A	ORF1ab	ORF1ab	COVID-19	G R S L	View
53	37376693	T851C	ORF1ab	ORF1ab	COVID-19	G R S L	View
54	37376693	G28436T	N	N	COVID-19	G R S L	View
55	37376693	G26167T	ORF3a	ORF3a	COVID-19	G R S L	View
56	37376693	V259L	ORF3a	ORF3a	COVID-19	G R S L	View
57	37376693	G2894A	ORF1ab	ORF1ab	COVID-19	G R S L	View
58	37376693	C14117T	ORF1ab	ORF1ab	COVID-19	G R S L	View
59	37376693	A26530G	M	M	COVID-19	G R S L	View
60	37376693	R346K	S	S	COVID-19	G R S L	View
61	37376693	G22599A	S	S	COVID-19	G R S L	View
62	37376693	C14805T	ORF1ab	ORF1ab	COVID-19	G R S L	View
63	37376693	C2470T	ORF1ab	ORF1ab	COVID-19	G R S L	View
64	37376693	T19632C	ORF1ab	ORF1ab	COVID-19	G R S L	View
65	37376693	G23628A	S	S	COVID-19	G R S L	View
66	37376693	G6850T	S	S	COVID-19	G R S L	View
67	37376693	S689N	S	S	COVID-19	G R S L	View
68	37376693	M585T	ORF1ab	ORF1ab	COVID-19	G R S L	View
69	37376693	T2019C	ORF1a	ORF1a	COVID-19	G R S L	View

Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note

D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.

G
The study mentioned the virus genotype/subtype information.

R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.

S
The study provided sequence information or accession numbers.

L
The study provided the geographic region/country of data origin.

C
The study provided clinical baseline information.

I
The study involved information related to immune.

T
The study involved host target genes.