All Curated Mutation Sites in SARS-CoV-2 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

Show All
  
ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: COVID-19-37469462
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 37469462 G446V
S
S
COVID-19
G
R
L
View
2 37469462 P499R
S
S
COVID-19
G
R
L
View
3 37469462 S371F
S
S
COVID-19
G
R
L
View
4 37469462 T478K
S
S
COVID-19
G
R
L
View
5 37469462 L452R
S
S
COVID-19
G
R
L
View
6 37469462 D614G
S
S
COVID-19
G
R
L
View
7 37469462 D950N
S
S
COVID-19
G
R
L
View
8 37469462 P681R
S
S
COVID-19
G
R
L
View
9 37469462 T19R
S
S
COVID-19
G
R
L
View
10 37469462 K417N
S
S
COVID-19
G
R
I
L
View
11 37469462 N501Y
S
S
COVID-19
G
R
I
L
View
12 37469462 A570D
S
S
COVID-19
G
R
L
View
13 37469462 D1118H
S
S
COVID-19
G
R
L
View
14 37469462 S982A
S
S
COVID-19
G
R
L
View
15 37469462 L212I
S
S
COVID-19
R
L
View
16 37469462 N856K
S
S
COVID-19
R
L
View
17 37469462 N969K
S
S
COVID-19
R
L
View
18 37469462 R190S
S
S
COVID-19
R
L
View
19 37469462 T1027I
S
S
COVID-19
R
L
View
20 37469462 T547K
S
S
COVID-19
R
L
View
21 37469462 V1176F
S
S
COVID-19
R
L
View
22 37469462 Y145D
S
S
COVID-19
R
L
View
23 37469462 Y505H
S
S
COVID-19
R
L
View
24 37469462 679_681del
S
S
COVID-19
R
L
View
25 37469462 S686A
S
S
COVID-19
R
L
View
26 37469462 E154K
S
S
COVID-19
R
L
View
27 37469462 E484K
S
S
COVID-19
R
L
View
28 37469462 H1101D
S
S
COVID-19
R
L
View
29 37469462 Q1071H
S
S
COVID-19
R
L
View
30 37469462 T716I
S
S
COVID-19
R
L
View
31 37469462 N679K
S
S
COVID-19
R
L
View
32 37469462 Q677H
S
S
COVID-19
R
L
View
33 37469462 N764K
S
S
COVID-19
R
L
View
34 37469462 P681H
S
S
COVID-19
R
L
View
35 37469462 E156G
S
S
COVID-19
R
L
View
36 37469462 G142D
S
S
COVID-19
R
L
View
37 37469462 T95I
S
S
COVID-19
R
L
View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.