All Curated Mutation Sites in SARS-CoV-2

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The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.

Browse Data by Virus Gene/Protein/Region, Disease OR Description

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Virus Gene/Protein

Disease

Description

For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

Furin cleavage site

Methyltransferase

Non-coding region

Keyword: COVID-19-37529147

ID	PMID	Mutation	Gene/Protein/Region	Encoding Gene/Protein	Disease	Description	Detail
1	37529147	Q954H	S	S	COVID-19	G R S L	View
2	37529147	T19I	S	S	COVID-19	G R S L	View
3	37529147	D405N	RBD	S	COVID-19	G R S L	View
4	37529147	E484A	RBD	S	COVID-19	G R S L	View
5	37529147	F486V	RBD	S	COVID-19	G R S L	View
6	37529147	K417N	RBD	S	COVID-19	G R S L	View
7	37529147	L452R	RBD	S	COVID-19	G R S L	View
8	37529147	N440K	RBD	S	COVID-19	G R S L	View
9	37529147	N501Y	RBD	S	COVID-19	G R S L	View
10	37529147	Q498R	RBD	S	COVID-19	G R S L	View
11	37529147	R408S	RBD	S	COVID-19	G R S L	View
12	37529147	S477N	RBD	S	COVID-19	G R S L	View
13	37529147	T478K	RBD	S	COVID-19	G R S L	View
14	37529147	Y505H	RBD	S	COVID-19	G R S L	View
15	37529147	K444R	S	S	COVID-19	G R S L	View
16	37529147	L5F	S	S	COVID-19	G R S L	View
17	37529147	G142D	S	S	COVID-19	G R S L	View
18	37529147	V123G	S	S	COVID-19	G R S L	View
19	37529147	M19M	ORF6	ORF6	COVID-19	G R S L	View
20	37529147	T112I	NSP15	ORF1b	COVID-19	G R S L	View
21	37529147	L749L	RdRp	ORF1b	COVID-19	G R S L	View
22	37529147	I42V	NSP14	ORF1b	COVID-19	G R S L	View
23	37529147	T127N	NSP1	ORF1a	COVID-19	G R S L	View
24	37529147	Q493R	S	S	COVID-19	R S L	View
25	37529147	S704L	S	S	COVID-19	R S L	View
26	37529147	V213G	S	S	COVID-19	R S L	View
27	37529147	L17L	ORF7b	ORF7b	COVID-19	R S L	View
28	37529147	T223I	ORF3a	ORF3a	COVID-19	R S L	View
29	37529147	T64T	ORF3a	ORF3a	COVID-19	R S L	View
30	37529147	I65I	NSP9	ORF1a	COVID-19	R S L	View
31	37529147	E23E	NSP8	ORF1a	COVID-19	R S L	View
32	37529147	Q73Q	NSP8	ORF1a	COVID-19	R S L	View
33	37529147	D48D	NSP5	ORF1a	COVID-19	R S L	View
34	37529147	P132H	NSP5	ORF1a	COVID-19	R S L	View
35	37529147	R131R	NSP5	ORF1a	COVID-19	R S L	View
36	37529147	C88C	NSP4	ORF1a	COVID-19	R S L	View
37	37529147	F39L	NSP4	ORF1a	COVID-19	R S L	View
38	37529147	T327I	NSP4	ORF1a	COVID-19	R S L	View
39	37529147	T492I	NSP4	ORF1a	COVID-19	R S L	View
40	37529147	V290V	NSP4	ORF1a	COVID-19	R S L	View
41	37529147	A534A	NSP3	ORF1a	COVID-19	R S L	View
42	37529147	F106F	NSP3	ORF1a	COVID-19	R S L	View
43	37529147	K977K	NSP3	ORF1a	COVID-19	R S L	View
44	37529147	L1791L	NSP3	ORF1a	COVID-19	R S L	View
45	37529147	T24I	NSP3	ORF1a	COVID-19	R S L	View
46	37529147	Y828Y	NSP3	ORF1a	COVID-19	R S L	View
47	37529147	L274L	NSP2	ORF1a	COVID-19	R S L	View
48	37529147	R392C	NSP13	ORF1b	COVID-19	R S L	View
49	37529147	P314L	NSP12	ORF1b	COVID-19	R S L	View
50	37529147	S135R	NSP1	ORF1a	COVID-19	R S L	View
51	37529147	G19G	N	N	COVID-19	R S L	View
52	37529147	P13L	N	N	COVID-19	R S L	View
53	37529147	S413R	N	N	COVID-19	R S L	View
54	37529147	A63T	M	M	COVID-19	R S L	View
55	37529147	D163D	M	M	COVID-19	R S L	View
56	37529147	F112F	M	M	COVID-19	R S L	View
57	37529147	Q19E	M	M	COVID-19	R S L	View
58	37529147	A653V	S	S	COVID-19	G R S L	View
59	37529147	D1146D	S	S	COVID-19	G R S L	View
60	37529147	D614G	S	S	COVID-19	G R S L	View
61	37529147	D796Y	S	S	COVID-19	G R S L	View
62	37529147	H655Y	S	S	COVID-19	G R S L	View
63	37529147	N679K	S	S	COVID-19	G R S L	View
64	37529147	N764K	S	S	COVID-19	G R S L	View
65	37529147	N969K	S	S	COVID-19	G R S L	View
66	37529147	P681H	S	S	COVID-19	G R S L	View

Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note

D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.

G
The study mentioned the virus genotype/subtype information.

R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.

S
The study provided sequence information or accession numbers.

L
The study provided the geographic region/country of data origin.

C
The study provided clinical baseline information.

I
The study involved information related to immune.

T
The study involved host target genes.