All Curated Mutation Sites in SARS-CoV-2 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: COVID-19-37533831
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 37533831 G145D
S
S
COVID-19
G
R
S
L
View
2 37533831 D614G
S
S
COVID-19
G
R
S
L
View
3 37533831 D950N
S
S
COVID-19
G
R
S
L
View
4 37533831 E156G
S
S
COVID-19
G
R
S
L
View
5 37533831 L452R
S
S
COVID-19
G
R
S
L
View
6 37533831 P681R
S
S
COVID-19
G
R
S
L
View
7 37533831 T19R
S
S
COVID-19
G
R
S
L
View
8 37533831 T478K
S
S
COVID-19
G
R
S
L
View
9 37533831 A243del
S
S
COVID-19
G
R
S
L
View
10 37533831 A27S
S
S
COVID-19
G
R
S
L
View
11 37533831 A701V
S
S
COVID-19
G
R
S
L
View
12 37533831 D215G
S
S
COVID-19
G
R
S
L
View
13 37533831 D80A
S
S
COVID-19
G
R
S
L
View
14 37533831 E484K
S
S
COVID-19
G
R
S
L
View
15 37533831 K417N
S
S
COVID-19
G
R
S
L
View
16 37533831 L18F
S
S
COVID-19
G
R
S
L
View
17 37533831 L242del
S
S
COVID-19
G
R
S
L
View
18 37533831 L244del
S
S
COVID-19
G
R
S
L
View
19 37533831 A67V
S
S
COVID-19
G
R
S
L
View
20 37533831 H49Y
S
S
COVID-19
G
R
S
L
View
21 37533831 71delH
S
S
COVID-19
G
R
S
L
View
22 37533831 69delH
S
S
COVID-19
G
R
S
L
View
23 37533831 70delV
S
S
COVID-19
G
R
S
L
View
24 37533831 211delN
S
S
COVID-19
G
R
S
L
View
25 37533831 R346K
S
S
COVID-19
G
R
S
L
View
26 37533831 143delV
S
S
COVID-19
G
R
S
L
View
27 37533831 144delY
S
S
COVID-19
G
R
S
L
View
28 37533831 145delY
S
S
COVID-19
G
R
S
L
View
29 37533831 A475S
S
S
COVID-19
G
R
S
L
View
30 37533831 157delF
S
S
COVID-19
G
R
S
L
View
31 37533831 158delR
S
S
COVID-19
G
R
S
L
View
32 37533831 V289L
S
S
COVID-19
G
R
S
L
View
33 37533831 T95I
S
S
COVID-19
G
R
S
L
View
34 37533831 A222V
S
S
COVID-19
G
R
S
L
View
35 37533831 G143D
S
S
COVID-19
G
R
S
L
View
36 37533831 S255F
S
S
COVID-19
G
R
S
L
View
37 37533831 T716I
S
S
COVID-19
G
R
S
L
View
38 37533831 A570D
S
S
COVID-19
G
R
S
L
View
39 37533831 D1118H
S
S
COVID-19
G
R
S
L
View
40 37533831 N501Y
S
S
COVID-19
G
R
S
L
View
41 37533831 P681H
S
S
COVID-19
G
R
S
L
View
42 37533831 S982A
S
S
COVID-19
G
R
S
L
View
43 37533831 T761I
S
S
COVID-19
G
R
S
L
View
44 37533831 D138H
S
S
COVID-19
G
R
S
L
View
45 37533831 S98F
S
S
COVID-19
G
R
S
L
View
46 37533831 L179P
S
S
COVID-19
G
R
S
L
View
47 37533831 G446S
S
S
COVID-19
G
R
S
I
L
View
48 37533831 N440K
S
S
COVID-19
G
R
S
I
L
View
49 37533831 Q271R
S
S
COVID-19
G
R
S
L
View
50 37533831 A879V
S
S
COVID-19
G
R
S
L
View
51 37533831 D405N
S
S
COVID-19
G
R
S
L
View
52 37533831 D796Y
S
S
COVID-19
G
R
S
L
View
53 37533831 E484A
S
S
COVID-19
G
R
S
L
View
54 37533831 F486V
S
S
COVID-19
G
R
S
L
View
55 37533831 G142D
S
S
COVID-19
G
R
S
L
View
56 37533831 G339D
S
S
COVID-19
G
R
S
L
View
57 37533831 G496S
S
S
COVID-19
G
R
S
L
View
58 37533831 H655Y
S
S
COVID-19
G
R
S
L
View
59 37533831 L212I
S
S
COVID-19
G
R
S
L
View
60 37533831 L452Q
S
S
COVID-19
G
R
S
L
View
61 37533831 L981F
S
S
COVID-19
G
R
S
L
View
62 37533831 N679K
S
S
COVID-19
G
R
S
L
View
63 37533831 N764K
S
S
COVID-19
G
R
S
L
View
64 37533831 N856K
S
S
COVID-19
G
R
S
L
View
65 37533831 N969K
S
S
COVID-19
G
R
S
L
View
66 37533831 Q493R
S
S
COVID-19
G
R
S
L
View
67 37533831 Q498R
S
S
COVID-19
G
R
S
L
View
68 37533831 Q954H
S
S
COVID-19
G
R
S
L
View
69 37533831 R408S
S
S
COVID-19
G
R
S
L
View
70 37533831 S371F
S
S
COVID-19
G
R
S
L
View
71 37533831 S371L
S
S
COVID-19
G
R
S
L
View
72 37533831 S373P
S
S
COVID-19
G
R
S
L
View
73 37533831 S375F
S
S
COVID-19
G
R
S
L
View
74 37533831 S477N
S
S
COVID-19
G
R
S
L
View
75 37533831 S704L
S
S
COVID-19
G
R
S
L
View
76 37533831 T376A
S
S
COVID-19
G
R
S
L
View
77 37533831 T547K
S
S
COVID-19
G
R
S
L
View
78 37533831 V213G
S
S
COVID-19
G
R
S
L
View
79 37533831 Y505H
S
S
COVID-19
G
R
S
L
View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.