All Curated Mutation Sites in SARS-CoV-2 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: COVID-19-37564431
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 37564431 A262T
S
S
COVID-19
R
L
View
2 37564431 C525W
S
S
COVID-19
R
L
View
3 37564431 D111N
S
S
COVID-19
R
L
View
4 37564431 D228N
S
S
COVID-19
R
S
L
View
5 37564431 G103R
S
S
COVID-19
R
L
View
6 37564431 L387I
S
S
COVID-19
R
L
View
7 37564431 Q115H
S
S
COVID-19
R
S
L
View
8 37564431 Q474H
S
S
COVID-19
R
L
View
9 37564431 Q506H
S
S
COVID-19
R
L
View
10 37564431 T22I
S
S
COVID-19
R
L
View
11 37564431 T240S
S
S
COVID-19
R
L
View
12 37564431 C538W
S
S
COVID-19
R
L
View
13 37564431 Q675R
S
S
COVID-19
R
L
View
14 37564431 R685P
S
S
COVID-19
R
S
L
View
15 37564431 D820N
S
S
COVID-19
R
S
L
View
16 37564431 D830N
S
S
COVID-19
R
S
L
View
17 37564431 E224K
S
S
COVID-19
R
S
L
View
18 37564431 D614G
S
S
COVID-19
R
S
L
View
19 37564431 A1290G
S
S
COVID-19
R
S
L
View
20 37564431 A1841G
S
S
COVID-19
R
S
L
View
21 37564431 A2409C
S
S
COVID-19
R
S
L
View
22 37564431 A2481C
S
S
COVID-19
R
S
L
View
23 37564431 A942G
S
S
COVID-19
R
S
L
View
24 37564431 C882T
S
S
COVID-19
R
S
L
View
25 37564431 D848N
S
S
COVID-19
R
L
View
26 37564431 G1662A
S
S
COVID-19
R
S
L
View
27 37564431 G2054C
S
S
COVID-19
R
S
L
View
28 37564431 G2458A
S
S
COVID-19
R
S
L
View
29 37564431 G2488A
S
S
COVID-19
R
S
L
View
30 37564431 G345C
S
S
COVID-19
R
S
L
View
31 37564431 G670A
S
S
COVID-19
R
S
L
View
32 37564431 G682A
S
S
COVID-19
R
S
L
View
33 37564431 P863H
S
S
COVID-19
R
L
View
34 37564431 R847K
S
S
COVID-19
R
L
View
35 37564431 T1446G
S
S
COVID-19
R
S
L
View
36 37564431 T1506G
S
S
COVID-19
R
S
L
View
37 37564431 T237C
S
S
COVID-19
R
S
L
View
38 37564431 T2394G
S
S
COVID-19
R
S
L
View
39 37564431 T2477G
S
S
COVID-19
R
S
L
View
40 37564431 T2514G
S
S
COVID-19
R
S
L
View
41 37564431 V11I
S
S
COVID-19
R
L
View
42 37564431 V826G
S
S
COVID-19
R
S
L
View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.