All Curated Mutation Sites in SARS-CoV-2 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: COVID-19-37595664
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 37595664 L18F
S
S
COVID-19
R
S
L
View
2 37595664 T19R
S
S
COVID-19
R
S
L
View
3 37595664 T20N
S
S
COVID-19
R
S
L
View
4 37595664 P26S
S
S
COVID-19
R
S
L
View
5 37595664 L54F
S
S
COVID-19
R
S
L
View
6 37595664 D80A
S
S
COVID-19
R
S
L
View
7 37595664 T95I
S
S
COVID-19
R
S
L
View
8 37595664 N138D
S
S
COVID-19
R
S
L
View
9 37595664 N138Y
S
S
COVID-19
R
S
L
View
10 37595664 G142D
S
S
COVID-19
R
S
L
View
11 37595664 M153T
S
S
COVID-19
R
S
L
View
12 37595664 D178N
S
S
COVID-19
R
S
L
View
13 37595664 R190S
S
S
COVID-19
R
S
L
View
14 37595664 D215G
S
S
COVID-19
R
S
L
View
15 37595664 K417N
S
S
COVID-19
R
S
L
View
16 37595664 K417T
S
S
COVID-19
R
S
L
View
17 37595664 L452R
S
S
COVID-19
R
S
L
View
18 37595664 S477I
S
S
COVID-19
R
S
L
View
19 37595664 T478K
S
S
COVID-19
R
S
L
View
20 37595664 E484K
S
S
COVID-19
R
S
L
View
21 37595664 N501Y
S
S
COVID-19
R
S
L
View
22 37595664 K558R
S
S
COVID-19
R
S
L
View
23 37595664 A570D
S
S
COVID-19
R
S
L
View
24 37595664 D614G
S
S
COVID-19
R
S
L
View
25 37595664 H655Y
S
S
COVID-19
R
S
L
View
26 37595664 Q675H
S
S
COVID-19
R
S
L
View
27 37595664 A701V
S
S
COVID-19
R
S
L
View
28 37595664 E702V
S
S
COVID-19
R
S
L
View
29 37595664 T716I
S
S
COVID-19
R
S
L
View
30 37595664 L822F
S
S
COVID-19
R
S
L
View
31 37595664 A829T
S
S
COVID-19
R
S
L
View
32 37595664 G832D
S
S
COVID-19
R
S
L
View
33 37595664 I850L
S
S
COVID-19
R
S
L
View
34 37595664 A899S
S
S
COVID-19
R
S
L
View
35 37595664 I931V
S
S
COVID-19
R
S
L
View
36 37595664 D950N
S
S
COVID-19
R
S
L
View
37 37595664 S982A
S
S
COVID-19
R
S
L
View
38 37595664 T1027I
S
S
COVID-19
R
S
L
View
39 37595664 D1118H
S
S
COVID-19
R
S
L
View
40 37595664 V1176F
S
S
COVID-19
R
S
L
View
41 37595664 M1237V
S
S
COVID-19
R
S
L
View
42 37595664 C1247F
S
S
COVID-19
R
S
L
View
43 37595664 P681H
S
S
COVID-19
R
S
L
View
44 37595664 P681R
S
S
COVID-19
R
S
L
View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.