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Virus Gene/Protein ORF1a ORF1b ORF3a S E M N ORF7a ORF7b ORF8 ORF1ab ORF9b ORF10 ORF6 ORF9c

Disease COVID-19All Cell line Cystic Fibrosis Pediatric Multisystem Inflammatory Disease, COVID-19 related Thrombosis, COVID-19 related HIV Infections

Description Genotype/Subtype Immune Target gene Clinical data Treatment Location Sequence data

For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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ORF1a

  

ORF1b

  

ORF3a

  

3CLpro

  

3'UTR

  

5'UTR

  

RBD

  

ORF7b-ORF8

  

upstream of N

  

Furin cleavage site

  

E

  

endoRNase

  

Exonuclease

  

S

  

NSP13

  

NSP3

  

M

  

Mpro

  

Methyltransferase

  

N

  

NSP14

  

NSP12

  

Non-coding region

  

NP

  

NS3

  

NS7a

  

NS7b

  

NS8

  

NSP5

  

NSP1

  

NSP10

  

NSP11

  

NSP15

  

NSP16

  

NSP2

  

NSP4

  

NSP6

  

NSP7

  

NSP8

  

NSP9

  

NTD

  

ORF8

  

ORF1ab

  

ORF9b

  

ORF10

  

ORF3

  

ORF6

  

ORF7a

  

ORF7b

  

ORF9

  

ORF9c

  

PLpro

  

RdRp

  

RBM

  

Replicase

  

RNA primase

  

• Mutation
• Sequence

ID	PMID	Mutation	Gene/Protein/Region	Encoding Gene/Protein	Disease	Description	Detail
1	37737624	E484A	S	S	COVID-19	G S L	View
2	37737624	K417N	S	S	COVID-19	G S L	View
3	37737624	P681H	S	S	COVID-19	G S L	View
4	37737624	D796Y	S	S	COVID-19	G S L	View
5	37737624	N764K	S	S	COVID-19	G S L	View
6	37737624	A23013C	S	S	COVID-19	G S L	View
7	37737624	A23040G	S	S	COVID-19	G S L	View
8	37737624	A23055G	S	S	COVID-19	G S L	View
9	37737624	A23063T	S	S	COVID-19	G S L	View
10	37737624	A23403G	S	S	COVID-19	G S L	View
11	37737624	A24424T	S	S	COVID-19	G S L	View
12	37737624	A67V	S	S	COVID-19	G S L	View
13	37737624	C21762T	S	S	COVID-19	G S L	View
14	37737624	C21846T	S	S	COVID-19	G S L	View
15	37737624	C22674T	S	S	COVID-19	G S L	View
16	37737624	C22686T	S	S	COVID-19	G S L	View
17	37737624	C22995A	S	S	COVID-19	G S L	View
18	37737624	C23202A	S	S	COVID-19	G S L	View
19	37737624	C23525T	S	S	COVID-19	G S L	View
20	37737624	C23604A	S	S	COVID-19	G S L	View
21	37737624	C23854A	S	S	COVID-19	G S L	View
22	37737624	C24130A	S	S	COVID-19	G S L	View
23	37737624	C24503T	S	S	COVID-19	G S L	View
24	37737624	D614G	S	S	COVID-19	G S L	View
25	37737624	G142D	S	S	COVID-19	G S L	View
26	37737624	G21987A	S	S	COVID-19	G S L	View
27	37737624	G22578A	S	S	COVID-19	G S L	View
28	37737624	G22992A	S	S	COVID-19	G S L	View
29	37737624	G23048A	S	S	COVID-19	G S L	View
30	37737624	G23948T	S	S	COVID-19	G S L	View
31	37737624	G339D	S	S	COVID-19	G S L	View
32	37737624	G496S	S	S	COVID-19	G S L	View
33	37737624	H655Y	S	S	COVID-19	G S L	View
34	37737624	N856K	S	S	COVID-19	G S L	View
35	37737624	N969K	S	S	COVID-19	G S L	View
36	37737624	Q493R	S	S	COVID-19	G S L	View
37	37737624	S373P	S	S	COVID-19	G S L	View
38	37737624	S375F	S	S	COVID-19	G S L	View
39	37737624	S477N	S	S	COVID-19	G S L	View
40	37737624	T22673C	S	S	COVID-19	G S L	View
41	37737624	T22679C	S	S	COVID-19	G S L	View
42	37737624	T23075C	S	S	COVID-19	G S L	View
43	37737624	T23599G	S	S	COVID-19	G S L	View
44	37737624	T24469A	S	S	COVID-19	G S L	View
45	37737624	T478K	S	S	COVID-19	G S L	View
46	37737624	T547K	S	S	COVID-19	G S L	View
47	37737624	N679K	S	S	COVID-19	G S L	View
48	37737624	G22813T	S	S	COVID-19	G S L	View
49	37737624	G22898A	S	S	COVID-19	G S L	View
50	37737624	G446S	S	S	COVID-19	G S L	View
51	37737624	N440K	S	S	COVID-19	G S L	View
52	37737624	T22882G	S	S	COVID-19	G S L	View
53	37737624	21765_21770del	S	S	COVID-19	G S L	View
54	37737624	22194_22196del	S	S	COVID-19	G S L	View
55	37737624	22205insGAGCCAGAA	S	S	COVID-19	G S L	View
56	37737624	69_70del	S	S	COVID-19	G S L	View
57	37737624	T95I	S	S	COVID-19	G S L	View
58	37737624	143_145del	S	S	COVID-19	G S L	View
59	37737624	212del	S	S	COVID-19	G S L	View
60	37737624	215insEPE	S	S	COVID-19	G S L	View
61	37737624	S371L	S	S	COVID-19	G S L	View
62	37737624	Q498R	S	S	COVID-19	G S L	View
63	37737624	N501Y	S	S	COVID-19	G S L	View
64	37737624	Y505H	S	S	COVID-19	G S L	View
65	37737624	Q954H	S	S	COVID-19	G S L	View
66	37737624	L981F	S	S	COVID-19	G S L	View
67	37737624	A11537G	ORF1ab	ORF1ab	COVID-19	G S L	View
68	37737624	A18163G	ORF1ab	ORF1ab	COVID-19	G S L	View
69	37737624	A2832G	ORF1ab	ORF1ab	COVID-19	G S L	View
70	37737624	C10029T	ORF1ab	ORF1ab	COVID-19	G S L	View
71	37737624	C10449A	ORF1ab	ORF1ab	COVID-19	G S L	View
72	37737624	C14408T	ORF1ab	ORF1ab	COVID-19	G S L	View
73	37737624	G11287T	ORF1ab	ORF1ab	COVID-19	G S L	View
74	37737624	G8393A	ORF1ab	ORF1ab	COVID-19	G S L	View
75	37737624	P3395H	ORF1ab	ORF1ab	COVID-19	G S L	View
76	37737624	6513_6515del	ORF1ab	ORF1ab	COVID-19	G S L	View
77	37737624	11288_11296del	ORF1ab	ORF1ab	COVID-19	G S L	View
78	37737624	K856R	ORF1ab	ORF1ab	COVID-19	G S L	View
79	37737624	2084del	ORF1ab	ORF1ab	COVID-19	G S L	View
80	37737624	A2710T	ORF1ab	ORF1ab	COVID-19	G S L	View
81	37737624	T3255I	ORF1ab	ORF1ab	COVID-19	G S L	View
82	37737624	3674_3676del	ORF1ab	ORF1ab	COVID-19	G S L	View
83	37737624	L3674F	ORF1ab	ORF1ab	COVID-19	G S L	View
84	37737624	I3758V	ORF1ab	ORF1ab	COVID-19	G S L	View
85	37737624	P4715L	ORF1ab	ORF1ab	COVID-19	G S L	View
86	37737624	I5967V	ORF1ab	ORF1ab	COVID-19	G S L	View
87	37737624	C28311T	N	N	COVID-19	G S L	View
88	37737624	G28881A	N	N	COVID-19	G S L	View
89	37737624	G28882A	N	N	COVID-19	G S L	View
90	37737624	G28883C	N	N	COVID-19	G S L	View
91	37737624	P13L	N	N	COVID-19	G S L	View
92	37737624	28362_28370del	N	N	COVID-19	G S L	View
93	37737624	31_33del	N	N	COVID-19	G S L	View
94	37737624	A26530G	M	M	COVID-19	G S L	View
95	37737624	A63T	M	M	COVID-19	G S L	View
96	37737624	C26577G	M	M	COVID-19	G S L	View
97	37737624	G26709A	M	M	COVID-19	G S L	View
98	37737624	Q19E	M	M	COVID-19	G S L	View
99	37737624	D3G	M	M	COVID-19	G S L	View
100	37737624	C26270T	E	E	COVID-19	G S L	View
101	37737624	T9I	E	E	COVID-19	G S L	View
102	37737624	E484K	S	S	COVID-19	G S L	View
103	37737624	L452R	S	S	COVID-19	G S L	View