All Curated Mutation Sites in SARS-CoV-2 
Back to Mutation Home

 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

Show All
  
ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: COVID-19-37903828
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 37903828 L452R
S
S
COVID-19
G
R
L
View
2 37903828 P681R
S
S
COVID-19
G
R
View
3 37903828 E484Q
RBD
S
COVID-19
G
R
View
4 37903828 D614G
S
S
COVID-19
R
L
View
5 37903828 N501Y
S
S
COVID-19
R
L
View
6 37903828 P681H
S
S
COVID-19
R
L
View
7 37903828 T716I
S
S
COVID-19
R
View
8 37903828 A570D
S
S
COVID-19
R
View
9 37903828 D796Y
S
S
COVID-19
R
View
10 37903828 E1188L
S
S
COVID-19
R
View
11 37903828 N764K
S
S
COVID-19
R
View
12 37903828 N856K
S
S
COVID-19
R
View
13 37903828 R1000L
S
S
COVID-19
R
View
14 37903828 D405N
RBD
S
COVID-19
R
L
View
15 37903828 F377Y
RBD
S
COVID-19
R
View
16 37903828 G339D
RBD
S
COVID-19
R
View
17 37903828 K417N
RBD
S
COVID-19
R
View
18 37903828 S371F
RBD
S
COVID-19
R
View
19 37903828 S373P
RBD
S
COVID-19
R
View
20 37903828 T478K
RBD
S
COVID-19
R
L
View
21 37903828 Q77E
ORF9b
ORF9b
COVID-19
R
L
View
22 37903828 G38R
ORF9b
ORF9b
COVID-19
R
L
View
23 37903828 G38V
ORF9b
ORF9b
COVID-19
R
L
View
24 37903828 L64F
ORF9b
ORF9b
COVID-19
R
L
View
25 37903828 R32L
ORF9b
ORF9b
COVID-19
R
L
View
26 37903828 T60A
ORF9b
ORF9b
COVID-19
R
L
View
27 37903828 P10S
ORF9b
ORF9b
COVID-19
R
L
View
28 37903828 Y73C
ORF8
ORF8
COVID-19
R
L
View
29 37903828 R52I
ORF8
ORF8
COVID-19
R
L
View
30 37903828 E92K
ORF8
ORF8
COVID-19
R
L
View
31 37903828 G96S
ORF8
ORF8
COVID-19
R
L
View
32 37903828 T26I
ORF8
ORF8
COVID-19
R
L
View
33 37903828 W45L
ORF8
ORF8
COVID-19
R
View
34 37903828 D34G
ORF8
ORF8
COVID-19
R
View
35 37903828 F120L
ORF8
ORF8
COVID-19
R
View
36 37903828 F3L
ORF8
ORF8
COVID-19
R
View
37 37903828 W45R
ORF8
ORF8
COVID-19
R
View
38 37903828 T40I
ORF7b
ORF7b
COVID-19
R
L
View
39 37903828 E33A
ORF7b
ORF7b
COVID-19
R
L
View
40 37903828 H42Y
ORF7b
ORF7b
COVID-19
R
L
View
41 37903828 V21F
ORF7b
ORF7b
COVID-19
R
L
View
42 37903828 N38T
ORF7a
ORF7a
COVID-19
R
L
View
43 37903828 S5L
ORF7a
ORF7a
COVID-19
R
L
View
44 37903828 A15S
ORF7a
ORF7a
COVID-19
R
L
View
45 37903828 D36Y
ORF7a
ORF7a
COVID-19
R
L
View
46 37903828 T120I
ORF7a
ORF7a
COVID-19
R
L
View
47 37903828 V82A
ORF7a
ORF7a
COVID-19
R
L
View
48 37903828 A43S
ORF7a
ORF7a
COVID-19
R
L
View
49 37903828 I14T
ORF6
ORF6
COVID-19
R
L
View
50 37903828 S41P
ORF6
ORF6
COVID-19
R
L
View
51 37903828 D61L
ORF6
ORF6
COVID-19
R
L
View
52 37903828 K42N
ORF6
ORF6
COVID-19
R
L
View
53 37903828 P57L
ORF6
ORF6
COVID-19
R
L
View
54 37903828 S43P
ORF6
ORF6
COVID-19
R
L
View
55 37903828 W27L
ORF6
ORF6
COVID-19
R
L
View
56 37903828 E13D
ORF6
ORF6
COVID-19
R
L
View
57 37903828 P42L
ORF3a
ORF3a
COVID-19
R
L
View
58 37903828 S26L
ORF3a
ORF3a
COVID-19
R
L
View
59 37903828 Q57H
ORF3a
ORF3a
COVID-19
R
L
View
60 37903828 S253P
ORF3a
ORF3a
COVID-19
R
L
View
61 37903828 L83F
ORF3a
ORF3a
COVID-19
R
View
62 37903828 A1918V
ORF1b
ORF1b
COVID-19
R
L
View
63 37903828 E1264D
ORF1b
ORF1b
COVID-19
R
L
View
64 37903828 P218L
ORF1b
ORF1b
COVID-19
R
L
View
65 37903828 P314L
ORF1b
ORF1b
COVID-19
R
L
View
66 37903828 T67I
ORF1b
ORF1b
COVID-19
R
View
67 37903828 K1383R
ORF1b
ORF1b
COVID-19
R
L
View
68 37903828 T1001I
ORF1a
ORF1a
COVID-19
R
L
View
69 37903828 A1708D
ORF1a
ORF1a
COVID-19
R
L
View
70 37903828 I2230T
ORF1a
ORF1a
COVID-19
R
L
View
71 37903828 L10S
NTD
S
COVID-19
R
View
72 37903828 L5Y
NTD
S
COVID-19
R
View
73 37903828 P26L
NTD
S
COVID-19
R
View
74 37903828 S13L
NTD
S
COVID-19
R
View
75 37903828 S60A
NTD
S
COVID-19
R
View
76 37903828 T19R
NTD
S
COVID-19
R
View
77 37903828 V3L
NTD
S
COVID-19
R
View
78 37903828 R203K
N
N
COVID-19
R
L
View
79 37903828 T265I
N
N
COVID-19
R
L
View
80 37903828 G204R
N
N
COVID-19
R
L
View
81 37903828 P80R
N
N
COVID-19
R
L
View
82 37903828 S235F
N
N
COVID-19
R
L
View
83 37903828 D3L
N
N
COVID-19
R
L
View
84 37903828 I82T
M
M
COVID-19
R
L
View
85 37903828 L87F
M
M
COVID-19
R
L
View
86 37903828 L29F
M
M
COVID-19
R
L
View
87 37903828 A104V
M
M
COVID-19
R
L
View
88 37903828 A69S
M
M
COVID-19
R
L
View
89 37903828 H125Y
M
M
COVID-19
R
L
View
90 37903828 V70F
M
M
COVID-19
R
L
View
91 37903828 T175M
M
M
COVID-19
R
L
View
92 37903828 D160Y
M
M
COVID-19
R
View
93 37903828 T9I
E
E
COVID-19
R
L
View
94 37903828 P71L
E
E
COVID-19
R
L
View
95 37903828 P71S
E
E
COVID-19
R
L
View
96 37903828 R69G
E
E
COVID-19
R
L
View
97 37903828 T30I
E
E
COVID-19
R
L
View
98 37903828 V49L
E
E
COVID-19
R
L
View
99 37903828 A1818L COVID-19
R
L
View
100 37903828 G18V COVID-19
R
View
101 37903828 I33T COVID-19
R
View
102 37903828 P30L COVID-19
R
View
103 37903828 Q418H COVID-19
R
View
104 37903828 W45S COVID-19
R
View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.