All Curated Mutation Sites in SARS-CoV-2 
Back to Mutation Home

 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

Show All
  
ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: COVID-19-37965255
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 37965255 T883I
S
S
COVID-19
G
R
C
L
View
2 37965255 A570S
S
S
COVID-19
G
R
C
L
View
3 37965255 N1125S
S
S
COVID-19
G
R
C
L
View
4 37965255 A27S
S
S
COVID-19
G
R
C
L
View
5 37965255 D405N
S
S
COVID-19
G
R
C
L
View
6 37965255 D614G
S
S
COVID-19
G
R
C
L
View
7 37965255 D796Y
S
S
COVID-19
G
R
C
L
View
8 37965255 E484A
S
S
COVID-19
G
R
C
L
View
9 37965255 F486V
S
S
COVID-19
G
R
C
L
View
10 37965255 G142D
S
S
COVID-19
G
R
C
L
View
11 37965255 H655Y
S
S
COVID-19
G
R
C
L
View
12 37965255 K417N
S
S
COVID-19
G
R
C
L
View
13 37965255 L452R
S
S
COVID-19
G
R
C
L
View
14 37965255 N440K
S
S
COVID-19
G
R
C
L
View
15 37965255 N501Y
S
S
COVID-19
G
R
C
L
View
16 37965255 N679K
S
S
COVID-19
G
R
C
L
View
17 37965255 N764K
S
S
COVID-19
G
R
C
L
View
18 37965255 N969K
S
S
COVID-19
G
R
C
L
View
19 37965255 P681H
S
S
COVID-19
G
R
C
L
View
20 37965255 Q498R
S
S
COVID-19
G
R
C
L
View
21 37965255 Q954H
S
S
COVID-19
G
R
C
L
View
22 37965255 S477N
S
S
COVID-19
G
R
C
L
View
23 37965255 T19I
S
S
COVID-19
G
R
C
L
View
24 37965255 T478K
S
S
COVID-19
G
R
C
L
View
25 37965255 V213G
S
S
COVID-19
G
R
C
L
View
26 37965255 Y505H
S
S
COVID-19
G
R
C
L
View
27 37965255 A29I
ORF9b
ORF9b
COVID-19
G
R
C
L
View
28 37965255 V30L
ORF9b
ORF9b
COVID-19
G
R
C
L
View
29 37965255 D16G
ORF9b
ORF9b
COVID-19
G
R
C
L
View
30 37965255 P10S
ORF9b
ORF9b
COVID-19
G
R
C
L
View
31 37965255 F63H
ORF7a
ORF7a
COVID-19
G
R
C
L
View
32 37965255 H47Y
ORF7a
ORF7a
COVID-19
G
R
C
L
View
33 37965255 T223I
ORF3a
ORF3a
COVID-19
G
R
C
L
View
34 37965255 S997P
ORF1b
ORF1b
COVID-19
G
R
C
L
View
35 37965255 I2664V
ORF1b
ORF1b
COVID-19
G
R
C
L
View
36 37965255 T2432I
ORF1b
ORF1b
COVID-19
G
R
C
L
View
37 37965255 Y1648C
ORF1b
ORF1b
COVID-19
G
R
C
L
View
38 37965255 I1566V
ORF1b
ORF1b
COVID-19
G
R
C
L
View
39 37965255 P314L
ORF1b
ORF1b
COVID-19
G
R
C
L
View
40 37965255 R1315C
ORF1b
ORF1b
COVID-19
G
R
C
L
View
41 37965255 K3353R
ORF1a
ORF1a
COVID-19
G
R
C
L
View
42 37965255 L3667F
ORF1a
ORF1a
COVID-19
G
R
C
L
View
43 37965255 L3116F
ORF1a
ORF1a
COVID-19
G
R
C
L
View
44 37965255 L3352F
ORF1a
ORF1a
COVID-19
G
R
C
L
View
45 37965255 T2967I
ORF1a
ORF1a
COVID-19
G
R
C
L
View
46 37965255 S3949N
ORF1a
ORF1a
COVID-19
G
R
C
L
View
47 37965255 T1788M
ORF1a
ORF1a
COVID-19
G
R
C
L
View
48 37965255 T1840I
ORF1a
ORF1a
COVID-19
G
R
C
L
View
49 37965255 T4175I
ORF1a
ORF1a
COVID-19
G
R
C
L
View
50 37965255 G1307S
ORF1a
ORF1a
COVID-19
G
R
C
L
View
51 37965255 L3027F
ORF1a
ORF1a
COVID-19
G
R
C
L
View
52 37965255 P3395H
ORF1a
ORF1a
COVID-19
G
R
C
L
View
53 37965255 S135R
ORF1a
ORF1a
COVID-19
G
R
C
L
View
54 37965255 T3090I
ORF1a
ORF1a
COVID-19
G
R
C
L
View
55 37965255 T3255I
ORF1a
ORF1a
COVID-19
G
R
C
L
View
56 37965255 T842I
ORF1a
ORF1a
COVID-19
G
R
C
L
View
57 37965255 Q241K
N
N
COVID-19
G
R
C
L
View
58 37965255 S33F
N
N
COVID-19
G
R
C
L
View
59 37965255 G204R
N
N
COVID-19
G
R
C
L
View
60 37965255 R203K
N
N
COVID-19
G
R
C
L
View
61 37965255 S413R
N
N
COVID-19
G
R
C
L
View
62 37965255 A63T
M
M
COVID-19
G
R
C
L
View
63 37965255 D3N
M
M
COVID-19
G
R
C
L
View
64 37965255 Q19E
M
M
COVID-19
G
R
C
L
View
65 37965255 T91I
E
E
COVID-19
G
R
C
L
View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.