All Curated Mutation Sites in SARS-CoV-2 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

Show All
  
ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: COVID-19-38003257
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 38003257 F486V
S
S
COVID-19
G
R
S
L
View
2 38003257 L452R
S
S
COVID-19
G
R
S
L
View
3 38003257 R346T
S
S
COVID-19
G
R
S
L
View
4 38003257 N658S
S
S
COVID-19
G
R
S
L
View
5 38003257 D614G
S
S
COVID-19
G
R
S
L
View
6 38003257 D796Y
S
S
COVID-19
G
R
S
L
View
7 38003257 E484A
S
S
COVID-19
G
R
S
L
View
8 38003257 G142D
S
S
COVID-19
G
R
S
L
View
9 38003257 H655Y
S
S
COVID-19
G
R
S
L
View
10 38003257 K417N
S
S
COVID-19
G
R
S
L
View
11 38003257 N440K
S
S
COVID-19
G
R
S
L
View
12 38003257 N501Y
S
S
COVID-19
G
R
S
L
View
13 38003257 N679K
S
S
COVID-19
G
R
S
L
View
14 38003257 N764K
S
S
COVID-19
G
R
S
L
View
15 38003257 N969K
S
S
COVID-19
G
R
S
L
View
16 38003257 P681H
S
S
COVID-19
G
R
S
L
View
17 38003257 Q498R
S
S
COVID-19
G
R
S
L
View
18 38003257 Q954H
S
S
COVID-19
G
R
S
L
View
19 38003257 S373P
S
S
COVID-19
G
R
S
L
View
20 38003257 S375F
S
S
COVID-19
G
R
S
L
View
21 38003257 S477N
S
S
COVID-19
G
R
S
L
View
22 38003257 T478K
S
S
COVID-19
G
R
S
L
View
23 38003257 Y505H
S
S
COVID-19
G
R
S
L
View
24 38003257 F157L
S
S
COVID-19
G
R
S
L
View
25 38003257 G257S
S
S
COVID-19
G
R
S
L
View
26 38003257 G339H
S
S
COVID-19
G
R
S
L
View
27 38003257 G446S
S
S
COVID-19
G
R
S
L
View
28 38003257 I210V
S
S
COVID-19
G
R
S
L
View
29 38003257 N460K
S
S
COVID-19
G
R
S
L
View
30 38003257 W152R
S
S
COVID-19
G
R
S
L
View
31 38003257 K147E
S
S
COVID-19
G
R
S
L
View
32 38003257 L452Q
S
S
COVID-19
G
R
S
L
View
33 38003257 S704L
S
S
COVID-19
G
R
S
L
View
34 38003257 G339D
S
S
COVID-19
G
R
S
L
View
35 38003257 Q493R
S
S
COVID-19
G
R
S
L
View
36 38003257 A27S
S
S
COVID-19
G
R
S
L
View
37 38003257 D405N
S
S
COVID-19
G
R
S
L
View
38 38003257 R408S
S
S
COVID-19
G
R
S
L
View
39 38003257 S371F
S
S
COVID-19
G
R
S
L
View
40 38003257 T19I
S
S
COVID-19
G
R
S
L
View
41 38003257 T376A
S
S
COVID-19
G
R
S
L
View
42 38003257 V213G
S
S
COVID-19
G
R
S
L
View
43 38003257 A67V
S
S
COVID-19
G
R
S
L
View
44 38003257 G496S
S
S
COVID-19
G
R
S
L
View
45 38003257 L212I
S
S
COVID-19
G
R
S
L
View
46 38003257 L981F
S
S
COVID-19
G
R
S
L
View
47 38003257 N856K
S
S
COVID-19
G
R
S
L
View
48 38003257 S371L
S
S
COVID-19
G
R
S
L
View
49 38003257 T547K
S
S
COVID-19
G
R
S
L
View
50 38003257 T95I
S
S
COVID-19
G
R
S
L
View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.