All Curated Mutation Sites in SARS-CoV-2

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The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.

Browse Data by Virus Gene/Protein/Region, Disease OR Description

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Virus Gene/Protein

Disease

Description

For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

Furin cleavage site

Methyltransferase

Non-coding region

Keyword: COVID-19-38348230

ID	PMID	Mutation	Gene/Protein/Region	Encoding Gene/Protein	Disease	Description	Detail
1	38348230	E340V	S	S	COVID-19	D C L	View
2	38348230	P337R	S	S	COVID-19	C L	View
3	38348230	E340K	S	S	COVID-19	D C L	View
4	38348230	T19R	S	S	COVID-19	C L	View
5	38348230	T95I	S	S	COVID-19	C L	View
6	38348230	I101T	S	S	COVID-19	C L	View
7	38348230	G142D	S	S	COVID-19	C L	View
8	38348230	D178N	S	S	COVID-19	C L	View
9	38348230	E340A	S	S	COVID-19	C L	View
10	38348230	Q414R	S	S	COVID-19	C L	View
11	38348230	L452R	S	S	COVID-19	C L	View
12	38348230	T478K	S	S	COVID-19	C L	View
13	38348230	S494P	S	S	COVID-19	C L	View
14	38348230	D614G	S	S	COVID-19	C L	View
15	38348230	P681R	S	S	COVID-19	C L	View
16	38348230	D950N	S	S	COVID-19	C L	View
17	38348230	G15814A	RdRp	ORF1b	COVID-19	D C L	View
18	38348230	V792I	RdRp	ORF1b	COVID-19	D C L	View
19	38348230	V791I	RdRp	ORF1b	COVID-19	D C L	View
20	38348230	P93S	ORF8	ORF8	COVID-19	C L	View
21	38348230	T40I	ORF7b	ORF7b	COVID-19	C L	View
22	38348230	V82A	ORF7a	ORF7a	COVID-19	C L	View
23	38348230	T120I	ORF7a	ORF7a	COVID-19	C L	View
24	38348230	S26L	ORF3a	ORF3a	COVID-19	C L	View
25	38348230	A54S	ORF3a	ORF3a	COVID-19	C L	View
26	38348230	P314L	ORF1b	ORF1b	COVID-19	C L	View
27	38348230	G662S	ORF1b	ORF1b	COVID-19	C L	View
28	38348230	V783I	ORF1b	ORF1b	COVID-19	C L	View
29	38348230	P1000L	ORF1b	ORF1b	COVID-19	C L	View
30	38348230	R1078C	ORF1b	ORF1b	COVID-19	C L	View
31	38348230	R1502K	ORF1b	ORF1b	COVID-19	C L	View
32	38348230	A1868V	ORF1b	ORF1b	COVID-19	C L	View
33	38348230	A1918V	ORF1b	ORF1b	COVID-19	C L	View
34	38348230	V2287I	ORF1b	ORF1b	COVID-19	C L	View
35	38348230	V378L	ORF1a	ORF1a	COVID-19	C L	View
36	38348230	L631I	ORF1a	ORF1a	COVID-19	C L	View
37	38348230	E1209G	ORF1a	ORF1a	COVID-19	C L	View
38	38348230	A1306S	ORF1a	ORF1a	COVID-19	C L	View
39	38348230	V1750A	ORF1a	ORF1a	COVID-19	C L	View
40	38348230	E1909D	ORF1a	ORF1a	COVID-19	C L	View
41	38348230	P2046L	ORF1a	ORF1a	COVID-19	C L	View
42	38348230	P2287S	ORF1a	ORF1a	COVID-19	C L	View
43	38348230	V2930L	ORF1a	ORF1a	COVID-19	C L	View
44	38348230	R3012K	ORF1a	ORF1a	COVID-19	C L	View
45	38348230	T3255I	ORF1a	ORF1a	COVID-19	C L	View
46	38348230	D3526E	ORF1a	ORF1a	COVID-19	C L	View
47	38348230	T3646A	ORF1a	ORF1a	COVID-19	C L	View
48	38348230	L4319F	ORF1a	ORF1a	COVID-19	C L	View
49	38348230	R249K	NSP4	ORF1a	COVID-19	C L	View
50	38348230	E391G	NSP3	ORF1a	COVID-19	C L	View
51	38348230	L451L	NSP2	ORF1a	COVID-19	C L	View
52	38348230	V236I	NSP15	ORF1b	COVID-19	C L	View
53	38348230	R155C	NSP13	ORF1b	COVID-19	C L	View
54	38348230	R579K	NSP13	ORF1b	COVID-19	C L	View
55	38348230	L66F	NSP10	ORF1a	COVID-19	C L	View
56	38348230	R10Q	N	N	COVID-19	C L	View
57	38348230	A90S	N	N	COVID-19	C L	View
58	38348230	S202N	N	N	COVID-19	C L	View
59	38348230	R203M	N	N	COVID-19	C L	View
60	38348230	G215C	N	N	COVID-19	C L	View
61	38348230	D377Y	N	N	COVID-19	C L	View
62	38348230	I82T	M	M	COVID-19	C L	View

Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note

D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.

G
The study mentioned the virus genotype/subtype information.

R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.

S
The study provided sequence information or accession numbers.

L
The study provided the geographic region/country of data origin.

C
The study provided clinical baseline information.

I
The study involved information related to immune.

T
The study involved host target genes.