All Curated Mutation Sites in SARS-CoV-2 
Back to Mutation Home

 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

Show All
  
ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: COVID-19-38435775
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 38435775 D614G
S
S
COVID-19
G
C
L
View
2 38435775 T19R
S
S
COVID-19
G
C
L
View
3 38435775 T951
S
S
COVID-19
G
C
L
View
4 38435775 G142D
S
S
COVID-19
G
C
L
View
5 38435775 E156G
S
S
COVID-19
G
C
L
View
6 38435775 157delF
S
S
COVID-19
G
C
L
View
7 38435775 158delR
S
S
COVID-19
G
C
L
View
8 38435775 V213G
S
S
COVID-19
G
C
L
View
9 38435775 L452R
S
S
COVID-19
G
C
L
View
10 38435775 T478K
S
S
COVID-19
G
C
L
View
11 38435775 P681R
S
S
COVID-19
G
C
L
View
12 38435775 I850L
S
S
COVID-19
G
C
L
View
13 38435775 D950N
S
S
COVID-19
G
C
L
View
14 38435775 D63G
N
N
COVID-19
G
C
L
View
15 38435775 R203M
N
N
COVID-19
G
C
L
View
16 38435775 G215C
N
N
COVID-19
G
C
L
View
17 38435775 D377Y
N
N
COVID-19
G
C
L
View
18 38435775 G79X
M
M
COVID-19
G
C
L
View
19 38435775 I82T
M
M
COVID-19
G
C
L
View
20 38435775 S197T
M
M
COVID-19
G
C
L
View
21 38435775 69delH
S
S
COVID-19
G
C
L
View
22 38435775 70delV
S
S
COVID-19
G
C
L
View
23 38435775 I100T
S
S
COVID-19
G
C
L
View
24 38435775 144delY
S
S
COVID-19
G
C
L
View
25 38435775 N501Y
S
S
COVID-19
G
C
L
View
26 38435775 A570D
S
S
COVID-19
G
C
L
View
27 38435775 P681H
S
S
COVID-19
G
C
L
View
28 38435775 L699I
S
S
COVID-19
G
C
L
View
29 38435775 T716I
S
S
COVID-19
G
C
L
View
30 38435775 S982A
S
S
COVID-19
G
C
L
View
31 38435775 D1118H
S
S
COVID-19
G
C
L
View
32 38435775 D3L
N
N
COVID-19
G
C
L
View
33 38435775 D3E
N
N
COVID-19
G
C
L
View
34 38435775 R203K
N
N
COVID-19
G
C
L
View
35 38435775 G204R
N
N
COVID-19
G
C
L
View
36 38435775 S235F
N
N
COVID-19
G
C
L
View
37 38435775 P122L
N
N
COVID-19
G
C
L
View
38 38435775 T716T
S
S
COVID-19
C
L
View
39 38435775 Q27X
ORF8
ORF8
COVID-19
C
L
View
40 38435775 R52I
ORF8
ORF8
COVID-19
C
L
View
41 38435775 S67F
ORF8
ORF8
COVID-19
C
L
View
42 38435775 K68X
ORF8
ORF8
COVID-19
C
L
View
43 38435775 Y73C
ORF8
ORF8
COVID-19
C
L
View
44 38435775 E110X
ORF8
ORF8
COVID-19
C
L
View
45 38435775 119delD
ORF8
ORF8
COVID-19
C
L
View
46 38435775 120delF
ORF8
ORF8
COVID-19
C
L
View
47 38435775 T40I
ORF7b
ORF7b
COVID-19
C
L
View
48 38435775 T39I
ORF7a
ORF7a
COVID-19
C
L
View
49 38435775 S83L
ORF7a
ORF7a
COVID-19
C
L
View
50 38435775 V82A
ORF7a
ORF7a
COVID-19
C
L
View
51 38435775 T120I
ORF7a
ORF7a
COVID-19
C
L
View
52 38435775 K79-R79del
ORF7a
ORF7a
COVID-19
C
L
View
53 38435775 K16T
ORF3
ORF3a
COVID-19
C
L
View
54 38435775 S26L
ORF3
ORF3a
COVID-19
C
L
View
55 38435775 G100C
ORF3
ORF3a
COVID-19
C
L
View
56 38435775 W131L
ORF3
ORF3a
COVID-19
C
L
View
57 38435775 W131C
ORF3
ORF3a
COVID-19
C
L
View
58 38435775 R39K
NSP9
ORF1a
COVID-19
C
L
View
59 38435775 T77A
NSP6
ORF1a
COVID-19
C
L
View
60 38435775 106delS
NSP6
ORF1a
COVID-19
C
L
View
61 38435775 107delG
NSP6
ORF1a
COVID-19
C
L
View
62 38435775 108delF
NSP6
ORF1a
COVID-19
C
L
View
63 38435775 Q208R
NSP6
ORF1a
COVID-19
C
L
View
64 38435775 G283S
NSP5
ORF1a
COVID-19
C
L
View
65 38435775 P132H
NSP5
ORF1a
COVID-19
C
L
View
66 38435775 V242I
NSP4
ORF1a
COVID-19
C
L
View
67 38435775 T492I
NSP4
ORF1a
COVID-19
C
L
View
68 38435775 T6I
NSP3
ORF1a
COVID-19
C
L
View
69 38435775 T48I
NSP3
ORF1a
COVID-19
C
L
View
70 38435775 T183I
NSP3
ORF1a
COVID-19
C
L
View
71 38435775 E130D
NSP3
ORF1a
COVID-19
C
L
View
72 38435775 A488S
NSP3
ORF1a
COVID-19
C
L
View
73 38435775 G489S
NSP3
ORF1a
COVID-19
C
L
View
74 38435775 T725I
NSP3
ORF1a
COVID-19
C
L
View
75 38435775 A890D
NSP3
ORF1a
COVID-19
C
L
View
76 38435775 A1006V
NSP3
ORF1a
COVID-19
C
L
View
77 38435775 A1105T
NSP3
ORF1a
COVID-19
C
L
View
78 38435775 P1228L
NSP3
ORF1a
COVID-19
C
L
View
79 38435775 I1412T
NSP3
ORF1a
COVID-19
C
L
View
80 38435775 C1421F
NSP3
ORF1a
COVID-19
C
L
View
81 38435775 P1469S
NSP3
ORF1a
COVID-19
C
L
View
82 38435775 S1682F
NSP3
ORF1a
COVID-19
C
L
View
83 38435775 A1775V
NSP3
ORF1a
COVID-19
C
L
View
84 38435775 A205S
NSP2
ORF1a
COVID-19
C
L
View
85 38435775 E457K
NSP2
ORF1a
COVID-19
C
L
View
86 38435775 G517V
NSP2
ORF1a
COVID-19
C
L
View
87 38435775 K160R
NSP16
ORF1b
COVID-19
C
L
View
88 38435775 T112I
NSP15
ORF1b
COVID-19
C
L
View
89 38435775 S147G
NSP15
ORF1b
COVID-19
C
L
View
90 38435775 F329L
NSP15
ORF1b
COVID-19
C
L
View
91 38435775 I42V
NSP14
ORF1b
COVID-19
C
L
View
92 38435775 A394V
NSP14
ORF1b
COVID-19
C
L
View
93 38435775 P77L
NSP13
ORF1b
COVID-19
C
L
View
94 38435775 P323L
NSP12
ORF1b
COVID-19
C
L
View
95 38435775 Q468H
NSP12
ORF1b
COVID-19
C
L
View
96 38435775 G671S
NSP12
ORF1b
COVID-19
C
L
View
97 38435775 L138F
NSP10
ORF1a
COVID-19
C
L
View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.