All Curated Mutation Sites in SARS-CoV-2 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: COVID-19-38601946
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 38601946 C25810T
ORF3a
ORF3a
COVID-19
G
R
C
L
View
2 38601946 L140F
ORF3a
ORF3a
COVID-19
G
R
C
L
View
3 38601946 C8991T
ORF1a
ORF1a
COVID-19
G
R
C
L
View
4 38601946 A2909V
ORF1a
ORF1a
COVID-19
G
R
C
L
View
5 38601946 C22227T
S
S
COVID-19
G
R
C
L
View
6 38601946 A222V
S
S
COVID-19
G
R
C
L
View
7 38601946 C1403T
ORF1a
ORF1a
COVID-19
G
R
C
L
View
8 38601946 P380S
ORF1a
ORF1a
COVID-19
G
R
C
L
View
9 38601946 C5184T
ORF1a
ORF1a
COVID-19
G
R
C
L
View
10 38601946 P1640L
ORF1a
ORF1a
COVID-19
G
R
C
L
View
11 38601946 C9891T
ORF1a
ORF1a
COVID-19
G
R
C
L
View
12 38601946 A3209V
ORF1a
ORF1a
COVID-19
G
R
C
L
View
13 38601946 T11418C
ORF1a
ORF1a
COVID-19
G
R
C
L
View
14 38601946 V3718A
ORF1a
ORF1a
COVID-19
G
R
C
L
View
15 38601946 C11514T
ORF1a
ORF1a
COVID-19
G
R
C
L
View
16 38601946 T3750I
ORF1a
ORF1a
COVID-19
G
R
C
L
View
17 38601946 C26408T
E
E
COVID-19
G
R
C
L
View
18 38601946 S55F
E
E
COVID-19
G
R
C
L
View
19 38601946 C27509T
ORF7a
ORF7a
COVID-19
G
R
C
L
View
20 38601946 T39I
ORF7a
ORF7a
COVID-19
G
R
C
L
View
21 38601946 C14120T
ORF1b
ORF1b
COVID-19
G
R
C
L
View
22 38601946 P218L
ORF1b
ORF1b
COVID-19
G
R
C
L
View
23 38601946 G7042T
ORF1a
ORF1a
COVID-19
G
R
C
L
View
24 38601946 M2259I
ORF1a
ORF1a
COVID-19
G
R
C
L
View
25 38601946 G26558T
M
M
COVID-19
G
R
C
L
View
26 38601946 E12D
M
M
COVID-19
G
R
C
L
View
27 38601946 C26305T
E
E
COVID-19
G
R
C
L
View
28 38601946 L21F
E
E
COVID-19
G
R
C
L
View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.