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Virus Gene/Protein ORF1a ORF1b ORF3a S E M N ORF7a ORF7b ORF8 ORF1ab ORF9b ORF10 ORF6 ORF9c

Disease COVID-19All Cell line Cystic Fibrosis Pediatric Multisystem Inflammatory Disease, COVID-19 related Thrombosis, COVID-19 related HIV Infections

Description Genotype/Subtype Immune Target gene Clinical data Treatment Location Sequence data

For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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ORF1a

  

ORF1b

  

ORF3a

  

3CLpro

  

3'UTR

  

5'UTR

  

RBD

  

ORF7b-ORF8

  

upstream of N

  

Furin cleavage site

  

E

  

endoRNase

  

Exonuclease

  

S

  

NSP13

  

NSP3

  

M

  

Mpro

  

Methyltransferase

  

N

  

NSP14

  

NSP12

  

Non-coding region

  

NP

  

NS3

  

NS7a

  

NS7b

  

NS8

  

NSP5

  

NSP1

  

NSP10

  

NSP11

  

NSP15

  

NSP16

  

NSP2

  

NSP4

  

NSP6

  

NSP7

  

NSP8

  

NSP9

  

NTD

  

ORF8

  

ORF1ab

  

ORF9b

  

ORF10

  

ORF3

  

ORF6

  

ORF7a

  

ORF7b

  

ORF9

  

ORF9c

  

PLpro

  

RdRp

  

RBM

  

Replicase

  

RNA primase

  

• Mutation
• Sequence

ID	PMID	Mutation	Gene/Protein/Region	Encoding Gene/Protein	Disease	Description	Detail
1	38684722	T21656C	S	S	COVID-19	S C L	View
2	38684722	G21800T	S	S	COVID-19	S C L	View
3	38684722	G21830T	S	S	COVID-19	S C L	View
4	38684722	21992_21994del	S	S	COVID-19	S C L	View
5	38684722	T22092A	S	S	COVID-19	S C L	View
6	38684722	G22100A	S	S	COVID-19	S C L	View
7	38684722	G22103C	S	S	COVID-19	S C L	View
8	38684722	G22103A	S	S	COVID-19	S C L	View
9	38684722	G22203T	S	S	COVID-19	S C L	View
10	38684722	C22448T	S	S	COVID-19	S C L	View
11	38684722	C22550T	S	S	COVID-19	S C L	View
12	38684722	G22599C	S	S	COVID-19	S C L	View
13	38684722	T22667C	S	S	COVID-19	S C L	View
14	38684722	A22728G	S	S	COVID-19	S C L	View
15	38684722	T23018G	S	S	COVID-19	S C L	View
16	38684722	G23072A	S	S	COVID-19	S C L	View
17	38684722	G23073A	S	S	COVID-19	S C L	View
18	38684722	C23202A	S	S	COVID-19	S C L	View
19	38684722	G23405T	S	S	COVID-19	S C L	View
20	38684722	G23463T	S	S	COVID-19	S C L	View
21	38684722	G23463A	S	S	COVID-19	S C L	View
22	38684722	T23487G	S	S	COVID-19	S C L	View
23	38684722	C23589A	S	S	COVID-19	S C L	View
24	38684722	A23592C	S	S	COVID-19	S C L	View
25	38684722	A23598G	S	S	COVID-19	S C L	View
26	38684722	C24117T	S	S	COVID-19	S C L	View
27	38684722	G25145A	S	S	COVID-19	S C L	View
28	38684722	A25325T	S	S	COVID-19	S C L	View
29	38684722	G25352C	S	S	COVID-19	S C L	View
30	38684722	F32L	S	S	COVID-19	S C L	View
31	38684722	D80Y	S	S	COVID-19	S C L	View
32	38684722	V90F	S	S	COVID-19	S C L	View
33	38684722	144delY	S	S	COVID-19	S C L	View
34	38684722	M177K	S	S	COVID-19	S C L	View
35	38684722	E180K	S	S	COVID-19	S C L	View
36	38684722	G181R	S	S	COVID-19	S C L	View
37	38684722	R214L	S	S	COVID-19	S C L	View
38	38684722	L296F	S	S	COVID-19	S C L	View
39	38684722	P330S	S	S	COVID-19	S C L	View
40	38684722	R346T	S	S	COVID-19	S C L	View
41	38684722	Y369H	S	S	COVID-19	S C L	View
42	38684722	D389G	S	S	COVID-19	S C L	View
43	38684722	F486V	S	S	COVID-19	S C L	View
44	38684722	G504S	S	S	COVID-19	S C L	View
45	38684722	G504D	S	S	COVID-19	S C L	View
46	38684722	T547K	S	S	COVID-19	S C L	View
47	38684722	V615F	S	S	COVID-19	S C L	View
48	38684722	R634L	S	S	COVID-19	S C L	View
49	38684722	R634H	S	S	COVID-19	S C L	View
50	38684722	V642G	S	S	COVID-19	S C L	View
51	38684722	T676N	S	S	COVID-19	S C L	View
52	38684722	Q677P	S	S	COVID-19	S C L	View
53	38684722	N679S	S	S	COVID-19	S C L	View
54	38684722	A852V	S	S	COVID-19	S C L	View
55	38684722	E1195K	S	S	COVID-19	S C L	View
56	38684722	K1255X	S	S	COVID-19	S C L	View
57	38684722	V1264L	S	S	COVID-19	S C L	View
58	38684722	T13924G	ORF1b	ORF1b	COVID-19	S C L	View
59	38684722	A13928T	ORF1b	ORF1b	COVID-19	S C L	View
60	38684722	A14359C	ORF1b	ORF1b	COVID-19	S C L	View
61	38684722	G14831A	ORF1b	ORF1b	COVID-19	S C L	View
62	38684722	G14831T	ORF1b	ORF1b	COVID-19	S C L	View
63	38684722	T14996C	ORF1b	ORF1b	COVID-19	S C L	View
64	38684722	G15451A	ORF1b	ORF1b	COVID-19	S C L	View
65	38684722	T15682A	ORF1b	ORF1b	COVID-19	S C L	View
66	38684722	T15685A	ORF1b	ORF1b	COVID-19	S C L	View
67	38684722	G15769T	ORF1b	ORF1b	COVID-19	S C L	View
68	38684722	G15814A	ORF1b	ORF1b	COVID-19	D S C L	View
69	38684722	G15822A	ORF1b	ORF1b	COVID-19	S C L	View
70	38684722	G15822T	ORF1b	ORF1b	COVID-19	D S C L	View
71	38684722	T15835C	ORF1b	ORF1b	COVID-19	S C L	View
72	38684722	G15836T	ORF1b	ORF1b	COVID-19	D S C L	View
73	38684722	T15877C	ORF1b	ORF1b	COVID-19	S C L	View
74	38684722	W153G	ORF1b	ORF1b	COVID-19	S C L	View
75	38684722	Y154F	ORF1b	ORF1b	COVID-19	S C L	View
76	38684722	I298L	ORF1b	ORF1b	COVID-19	S C L	View
77	38684722	C455Y	ORF1b	ORF1b	COVID-19	S C L	View
78	38684722	C455F	ORF1b	ORF1b	COVID-19	S C L	View
79	38684722	M510T	ORF1b	ORF1b	COVID-19	S C L	View
80	38684722	G662S	ORF1b	ORF1b	COVID-19	S C L	View
81	38684722	Y739N	ORF1b	ORF1b	COVID-19	S C L	View
82	38684722	L740M	ORF1b	ORF1b	COVID-19	S C L	View
83	38684722	A768S	ORF1b	ORF1b	COVID-19	S C L	View
84	38684722	V783I	ORF1b	ORF1b	COVID-19	S C L	View
85	38684722	M785I	ORF1b	ORF1b	COVID-19	S C L	View
86	38684722	C790R	ORF1b	ORF1b	COVID-19	S C L	View
87	38684722	C790F	ORF1b	ORF1b	COVID-19	S C L	View
88	38684722	C804R	ORF1b	ORF1b	COVID-19	S C L	View
89	38684722	W162G	NSP12	ORF1b	COVID-19	S C L	View
90	38684722	Y163F	NSP12	ORF1b	COVID-19	S C L	View
91	38684722	I307L	NSP12	ORF1b	COVID-19	S C L	View
92	38684722	C464Y	NSP12	ORF1b	COVID-19	S C L	View
93	38684722	C464F	NSP12	ORF1b	COVID-19	S C L	View
94	38684722	M519T	NSP12	ORF1b	COVID-19	S C L	View
95	38684722	G671S	NSP12	ORF1b	COVID-19	S C L	View
96	38684722	Y748N	NSP12	ORF1b	COVID-19	S C L	View
97	38684722	L749M	NSP12	ORF1b	COVID-19	S C L	View
98	38684722	A777S	NSP12	ORF1b	COVID-19	S C L	View
99	38684722	V792I	NSP12	ORF1b	COVID-19	D S C L	View
100	38684722	M794I	NSP12	ORF1b	COVID-19	D S C L	View
101	38684722	C799R	NSP12	ORF1b	COVID-19	D S C L	View
102	38684722	C799F	NSP12	ORF1b	COVID-19	S C L	View
103	38684722	C813R	NSP12	ORF1b	COVID-19	S C L	View