All Curated Mutation Sites in SARS-CoV-2 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in SARS-CoV-2 related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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ORF1a
  
ORF1b
  
ORF3a
  
3CLpro
  
3'UTR
  
5'UTR
  
RBD
  
ORF7b-ORF8
  
upstream of N
  
Furin cleavage site
  
E
  
endoRNase
  
Exonuclease
  
S
  
NSP13
  
NSP3
  
M
  
Mpro
  
Methyltransferase
  
N
  
NSP14
  
NSP12
  
Non-coding region
  
NP
  
NS3
  
NS7a
  
NS7b
  
NS8
  
NSP5
  
NSP1
  
NSP10
  
NSP11
  
NSP15
  
NSP16
  
NSP2
  
NSP4
  
NSP6
  
NSP7
  
NSP8
  
NSP9
  
NTD
  
ORF8
  
ORF1ab
  
ORF9b
  
ORF10
  
ORF3
  
ORF6
  
ORF7a
  
ORF7b
  
ORF9
  
ORF9c
  
PLpro
  
RdRp
  
RBM
  
Replicase
  
RNA primase
  

Keyword: COVID-19-39015352
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 39015352 L50F
M
M
COVID-19
D
G
C
L
View
2 39015352 I213V
M
M
COVID-19
D
G
C
L
View
3 39015352 L227F
M
M
COVID-19
D
G
C
L
View
4 39015352 T21I
M
M
COVID-19
D
G
C
L
View
5 39015352 K90R
M
M
COVID-19
D
G
C
L
View
6 39015352 A191V
M
M
COVID-19
D
G
C
L
View
7 39015352 P132H
M
M
COVID-19
D
G
C
L
View
8 39015352 P108S
M
M
COVID-19
D
G
C
L
View
9 39015352 C16S
M
M
COVID-19
C
L
View
10 39015352 L32F
M
M
COVID-19
C
L
View
11 39015352 V91D
M
M
COVID-19
C
L
View
12 39015352 V91I
M
M
COVID-19
C
L
View
13 39015352 N95A
M
M
COVID-19
C
L
View
14 39015352 G143D
M
M
COVID-19
C
L
View
15 39015352 V157W
M
M
COVID-19
C
L
View
16 39015352 F159S
M
M
COVID-19
C
L
View
17 39015352 M162I
M
M
COVID-19
C
L
View
18 39015352 V171D
M
M
COVID-19
C
L
View
19 39015352 G174S
M
M
COVID-19
C
L
View
20 39015352 D176S
M
M
COVID-19
C
L
View
21 39015352 L177S
M
M
COVID-19
C
L
View
22 39015352 E178W
M
M
COVID-19
C
L
View
23 39015352 F181T
M
M
COVID-19
C
L
View
24 39015352 Y182N
M
M
COVID-19
C
L
View
25 39015352 A234V
M
M
COVID-19
C
L
View
26 39015352 H246R
M
M
COVID-19
C
L
View
27 39015352 D263Y
M
M
COVID-19
C
L
View
28 39015352 G278R
M
M
COVID-19
C
L
View
29 39015352 R279C
M
M
COVID-19
C
L
View
30 39015352 T280A
M
M
COVID-19
C
L
View
31 39015352 G283D
M
M
COVID-19
C
L
View
Contents
Description

The table shows all curated mutation sites of SARS-CoV-2 in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.